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Autonomic
Nervous
System
Introduction
to Autonomic
Nervous
System
The Autonomic nervous system (ANS)
is a part of the peripheral nervous
system that controls involuntary
processes in the body.
It's made up of two sets of nerves, the
sympathetic and parasympathetic
systems, which work against
each other to either excite or subdue
the body's functions.
Sympathetic Nervous System
• Sympathetic Preganglionic Neurons
• Sympathetic Ganglia
• Postganglionic Sympathetic Neurons
• Distribution of Sympathetic neurons
• Effect of Sympathetic stimulation
Organization: Sympathetic Nervous System
Sympathetic Nervous System
Also called Thoracolumbar system
 All preganglionic sympathetic fibers
• Arises from lateral horn of spinal cord
• Leave the spinal cord with the ventral roots of the spinal
nerve
• Cell body located in gray matter from T1-L2
Sympathetic trunk extend the entire length of spinal cord
Post ganglionic fibers pass to effector organ
Sympathetic Nervous System
All preganglionic sympathetic fibers-
• Arises from lateral horn of spinal cord
• Leave the spinal cord with the ventral roots of the spinal
nerve
• Cell body located in gray matter from T1-L2
Sympathetic Nervous System
• All preganglionic sympathetic fibers are:
 Short
 Myelinated
 Type B fiber
• Leave the spinal cord via ventral root
• Pass via the white rami communicates to the paravertebral
ganglia
• Terminates in sympathetic ganglia
• Synapses with postganglionic neurons
Sympathetic Nervous System
• Destination of the preganglionic fibers after reaching the
sympathetic trunk
• Preganglionic fibers after reaching the sympathetic trunk may-
1. Terminate in the same ganglia that it enters.
2. Pass upward & terminate in the other ganglia.
3. Pass downward & terminate in the other ganglia.
4. Leave the sympathetic trunk without synapsing & terminate in other
ganglia which lies outside the sympathetic trunk.
Sympathetic Ganglia
• Ganglia: Structures where synapsing between pre and
post ganglionic fibers occurs
• One preganglionic fiber synapses with several post
ganglionic neurons
• Important groups of sympathetic ganglia are-
1. Sympathetic trunk (Paravertebral ganglia)
2. Prevertebral ganglia
3. Peripheral ganglia
Sympathetic
Trunk
Ganglia
Postganglionic Sympathetic Neuron
• All Postganglionic Sympathetic Neuron arises from
sympathetic ganglia
• Cell body located in ganglion
• These are -
 Short &
 Nonmyelinated
 Type C fibers
Postganglionic Sympathetic Neuron
Postganglionic Sympathetic Fibers may-
Pass through gray ramus communicantes and re-enter
ventral root to reach a spinal nerve and innervate the-
Sweat gland
Blood vessels
Piloerector muscle
Postganglionic Sympathetic Neuron
Postganglionic Sympathetic Fibers may-
1. Reach a cranial nerve through communicating branch &
distributed through it
2. Pass into a vascular branch and distributed to branches of
vessels
3. Innervate the visceral organs
Distribution of Sympathetic neurons
Segmental level
1. T1,T2
2. T3,T4
3. T5 toT9
4. T10 to L2
5. T6 toT12
6. L1,L2
7. T1toT12
Area of distribution
Head & Neck
Thoracic viscera
Upper limb
Lower Limb
Upper Abdominal Viscera
Lower Abdominal Viscera
Thoracic & abdominal
Vessels
Effect of Sympathetic stimulation
System/organ
CVS
Heart
SAN
AVN
Purkinje Fibers
Myocardium
Blood Vessels
Effects
Cardiac stimulation
+ve Chronotropic Effect
+ve Dromotropic Effect
+ve Bathmotropic Effect
+ve Inotropic Effect
Vasoconstriction – Splanchnic Cutaneous
Vasodilatation-skeletal blood vessels
Effect of Sympathetic stimulation
System/organ
CVS
HR
SV
CO
SBP
DBP
PVR
Effects
Cardiac stimulation
Increases
Increases
Increases
Increases
Increases
Increases
Sympathetic
responses
Autonomic System.pptx

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Autonomic System.pptx

  • 2. Introduction to Autonomic Nervous System The Autonomic nervous system (ANS) is a part of the peripheral nervous system that controls involuntary processes in the body. It's made up of two sets of nerves, the sympathetic and parasympathetic systems, which work against each other to either excite or subdue the body's functions.
  • 3. Sympathetic Nervous System • Sympathetic Preganglionic Neurons • Sympathetic Ganglia • Postganglionic Sympathetic Neurons • Distribution of Sympathetic neurons • Effect of Sympathetic stimulation
  • 5. Sympathetic Nervous System Also called Thoracolumbar system  All preganglionic sympathetic fibers • Arises from lateral horn of spinal cord • Leave the spinal cord with the ventral roots of the spinal nerve • Cell body located in gray matter from T1-L2 Sympathetic trunk extend the entire length of spinal cord Post ganglionic fibers pass to effector organ
  • 6. Sympathetic Nervous System All preganglionic sympathetic fibers- • Arises from lateral horn of spinal cord • Leave the spinal cord with the ventral roots of the spinal nerve • Cell body located in gray matter from T1-L2
  • 7. Sympathetic Nervous System • All preganglionic sympathetic fibers are:  Short  Myelinated  Type B fiber • Leave the spinal cord via ventral root • Pass via the white rami communicates to the paravertebral ganglia • Terminates in sympathetic ganglia • Synapses with postganglionic neurons
  • 8. Sympathetic Nervous System • Destination of the preganglionic fibers after reaching the sympathetic trunk • Preganglionic fibers after reaching the sympathetic trunk may- 1. Terminate in the same ganglia that it enters. 2. Pass upward & terminate in the other ganglia. 3. Pass downward & terminate in the other ganglia. 4. Leave the sympathetic trunk without synapsing & terminate in other ganglia which lies outside the sympathetic trunk.
  • 9. Sympathetic Ganglia • Ganglia: Structures where synapsing between pre and post ganglionic fibers occurs • One preganglionic fiber synapses with several post ganglionic neurons • Important groups of sympathetic ganglia are- 1. Sympathetic trunk (Paravertebral ganglia) 2. Prevertebral ganglia 3. Peripheral ganglia
  • 11. Postganglionic Sympathetic Neuron • All Postganglionic Sympathetic Neuron arises from sympathetic ganglia • Cell body located in ganglion • These are -  Short &  Nonmyelinated  Type C fibers
  • 12. Postganglionic Sympathetic Neuron Postganglionic Sympathetic Fibers may- Pass through gray ramus communicantes and re-enter ventral root to reach a spinal nerve and innervate the- Sweat gland Blood vessels Piloerector muscle
  • 13. Postganglionic Sympathetic Neuron Postganglionic Sympathetic Fibers may- 1. Reach a cranial nerve through communicating branch & distributed through it 2. Pass into a vascular branch and distributed to branches of vessels 3. Innervate the visceral organs
  • 14.
  • 15. Distribution of Sympathetic neurons Segmental level 1. T1,T2 2. T3,T4 3. T5 toT9 4. T10 to L2 5. T6 toT12 6. L1,L2 7. T1toT12 Area of distribution Head & Neck Thoracic viscera Upper limb Lower Limb Upper Abdominal Viscera Lower Abdominal Viscera Thoracic & abdominal Vessels
  • 16. Effect of Sympathetic stimulation System/organ CVS Heart SAN AVN Purkinje Fibers Myocardium Blood Vessels Effects Cardiac stimulation +ve Chronotropic Effect +ve Dromotropic Effect +ve Bathmotropic Effect +ve Inotropic Effect Vasoconstriction – Splanchnic Cutaneous Vasodilatation-skeletal blood vessels
  • 17. Effect of Sympathetic stimulation System/organ CVS HR SV CO SBP DBP PVR Effects Cardiac stimulation Increases Increases Increases Increases Increases Increases