Ateroscleroza carotidiana si diabetul zaharat. Sexul conteaza?
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Ultrasonography Doppler is useful in differentiating carotid occlusion from near-occlusion. Near-occlusion is defined as severe stenosis at the bulb followed by collapse of the distal ICA (string sign). Total occlusion is characterized by absence of any flow in the extracranial ICA, while near-occlusion may show variable flow patterns. Doppler criteria for stenosis grading do not apply in near-occlusion/occlusion. CT or MR angiography can help confirm ultrasound findings of total versus near occlusion. Optimizing Doppler parameters is crucial to avoid false positive occlusion diagnoses.
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Ateroscleroza carotidiana si diabetul zaharat. Sexul conteaza?
- 1. Ateroscleroza carotidianaAteroscleroza carotidiana si diabetul zaharatsi diabetul zaharat Sexul conteaza?Sexul conteaza? Alexandru Andritoiu Spitalul Clinic de Urgenta Militar CraiovaCraiova
- 2. Metoda de studiuMetoda de studiu US CAR (B-mode)US CAR (B-mode) ACC Parametrii evaluati: CIMT (mm)-metoda automata Identificarea placilor ATS (frecventa %)
- 3. Lot de studiuLot de studiu n = 127n = 127 DZ tip 2 N = 52 Varsta:59+/-3.2 Non DZ N = 75 Varsta 61.37+/-3.7
- 4. Dinamica CIMT (FDinamica CIMT (F)) cu varstacu varsta 40-4940-49 50-5950-59 60-6960-69 70-8070-80 Non DZ tip 2 (n =35) 0.40+/-0.4 0.53+/-0.4 0.72+/-0.2 0.79+/-0.2 DZ tip 2 (n=23) 0.5+/-0.3 0.58+/-0.1 0.7+/-0.1 1.13+/-0.1 0 0.2 0.4 0.6 0.8 1 1.2 40-49 50-59 60-69 70-80 fara DZ DZ
- 5. Dinamica CIMT (B) cu varstaDinamica CIMT (B) cu varsta 40-4940-49 50-5950-59 60-6960-69 70-8070-80 Fara DZ tip 2 (n=40) 0.40+/-0.2 0.65+/-0.1 0.67+/-0.1 0.98+/-0.1 DZ tip 2 (n=29) 0.5+/-0.2 0.60+/-0.1 0.83+/-0.2 1.2+/-0.2 0 0.2 0.4 0.6 0.8 1 1.2 1.4 40-49 50-59 60-69 70-80 fara DZ DZ
- 6. Dinamica CIMT cu varstaDinamica CIMT cu varsta (B/F)(B/F) 0 0,2 0,4 0,6 0,8 1 1,2 40-49 50-59 60-69 70-80 F B In absenta DZ –tip 2
- 7. Dinamica CIMT cu varstaDinamica CIMT cu varsta (B/F)(B/F) 0 0,2 0,4 0,6 0,8 1 1,2 1,4 40-49 50-59 60-69 70-80 F B In prezenta DZ –tip 2
- 9. Frecventa placilor CAR (F/B)Frecventa placilor CAR (F/B) 8 12 57% 25% 12% 83% 30% 37,5% 0 10 20 30 40 50 60 70 80 90 40-49 50-59 60-69 70-80 F B N = 95 subiecti
- 10. Frecventa placilor CAR (F/B)Frecventa placilor CAR (F/B) 36% 17% 50%50% 0 10 20 30 40 50 60 F B non DZ DZ
- 11. Corelatii CIMT-Placa CARCorelatii CIMT-Placa CAR r =r = p<p< F (nF (n 5858)) 0.36 0.05 B (nB (n 6969 )) 0.70 0.001 Lot (nLot (n 127127)) 0.52 0.01 Ecuatia regresiei lineare Pearson
- 12. ConcluziiConcluzii DZ tip 2 se asociaza la ambele sexe cu hipertrofie medio-intimala si o freventa crescuta a placilor CAR, ca semne de ATS macrovasculara Frecventa placilor CAR la sexul F este mai redusa decat la sexul M, doar in absenta DZ tip 2 In prezenta DZ, frecventa placilor CAR este egala intre cele doua sexe CIMT se coreleaza cu prezenta placilor CAR la sexul M mai bine decat la sexul F