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Dr Anu Priya J
AntipsychoticsandGalactorrhea
AntipsychoticsandGalactorrhea
•Consumption ofcertain Antipsychotics,
notablyRisperidone leadstoasideeffectof
milkynippledischargeunrelated tothenormal
milkproduction ofbreast-feeding, termed as
galactorrhea.
WHY??
Reason: Increased level of Prolactin
Mechanism:
• Dopamine normally inhibits Prolactin
Antipsychotics decrease the level of Dopamine
When Dopamine is low, there is no inhibition of Prolactin
•Prolactin level rises, thereby causing galactorrhea

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Antipsychotics May Cause Galactorrhea Due to Increased Prolactin