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Antiarrhythmic Drugs and Cardiac Arrhythmias

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ANTIARRYTHMIC DRUGS TACHYCARDIAS Dr Kirsten Cohen
Normal Sinus Rhythm ,[object Object],[object Object],[object Object],[object Object],[object Object]
Conducting System ,[object Object],[object Object],[object Object],[object Object]
Conducting System ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cardiac Action Potential ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cardiac Action Potential ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cardiac Action Potential ,[object Object],[object Object],[object Object],[object Object]
Refractory Periods ,[object Object],[object Object],[object Object],[object Object]
SAN Pacemaker Potential ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SAN Pacemaker Potential ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SAN Pacemaker Potential ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Regulation of Cardiac APs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Regulation of Cardiac APs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What is an Arrhythmia ? ,[object Object],[object Object],[object Object]
What causes an arrhythmia? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Re-Entry Mechanism ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rationale for Antiarrhythmic Drugs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Vaughan-Williams Classification Digoxin. Adenosine. MgSO4. Atropine Other Verapamil Ca channel blockers IV Amiodarone K channel blockers III Metoprolol Beta Blockers II Lignocaine Na channel blockers Membrane Stabilisers I Example Mechanism Class
Class I A Agents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class I B Agents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
LIGNOCAINE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class I C Agents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class II Agents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ATENOLOL ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class III Agents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
AMIODARONE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Class IV Agents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
VERAPAMIL ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What does Adenosine Do? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ADENOSINE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ADENOSINE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
What does Digoxin Do? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DIGOXIN ,[object Object],[object Object],[object Object],[object Object]
 
Take-Home Message ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Antiarrhythmic Drugs and Cardiac Arrhythmias

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  • 18. Vaughan-Williams Classification Digoxin. Adenosine. MgSO4. Atropine Other Verapamil Ca channel blockers IV Amiodarone K channel blockers III Metoprolol Beta Blockers II Lignocaine Na channel blockers Membrane Stabilisers I Example Mechanism Class
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Editor's Notes

  1. Links AA drugs to a MOA Not all drugs are included – Some commonly used Some drugs overlap classes - Sotalol