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Angiogenesis And Direct Myocardial Revascularization

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Sungpil Han
Sungpil Han
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Angiogenesis and Direct Myocardial Revascularization 3. Preclinical Models and Experience to Date ๋ถ€์‚ฐ์˜ํ•™์ „๋ฌธ๋Œ€ํ•™์› ํ•œ์„ฑํ•„ [email_address]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
General Outline ,[object Object],[object Object],[object Object],[object Object]
Preclinical efforts ์–ด๋–ป๊ฒŒ Treat ํ•  ๊ฒƒ์ธ๊ฐ€ ? How do we treat ์–ด๋–ค ๋™๋ฌผ , ์–ด๋Š ๊ฒฝ๋กœ , ์–ด๋–ค ๋†๋„ Treat ํ•œ ๋’ค ํšจ๊ณผ๋ฅผ ์–ด๋–ป๊ฒŒ ํฌ์ฐฉ , ์‘์šฉํ•  ๊ฒƒ์ธ๊ฐ€ ? How do we capture the treatment effect CT, USG, MRI, ํ˜ˆ์ฒญํ•™ , ์กฐ์งํ•™ , ํ˜•ํƒœํ•™
I. ANIMAL MODEL SELECTION CRITERIA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ย 
[object Object]
II. MODELS OF MYOCARDIAL ISCHEMIA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Myocardial Ischemia or Infarction ,[object Object],[object Object],[object Object],[object Object]
Ameroid Constrictor Model
Ameroid Constrictor Model
Ameroid Constrictor Model ,[object Object],[object Object],[object Object],[object Object]
Ameroid Constrictor Model ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Minimally Invasive Coronary Stenosis Model for Imaging ,[object Object],[object Object],[object Object],[object Object]
Variation of Vineberg Direct Arterial Implantation Procedure ,[object Object],[object Object]
ย 
Microembolization Model ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Myocardial Infarction (Ligation) Model ,[object Object],[object Object],[object Object],[object Object],[object Object]
III. HINDLIMB ISCHEMIA MODEL ,[object Object],[object Object],[object Object],[object Object],[object Object]
Ariana G. Ojalvo, โ€œTherapeutic angiogenesis following intramuscular gene transfer of vascular endothelialgrowth factor 121 in a dog model of hindlimb ischemia,โ€ Electronic Journal of Biotechnology I 6, no. 3 (December 15, 2003)
์„ธ๊ฐ€์ง€ ์น˜๋ฃŒ์  ์ ‘๊ทผ๋ฒ• ProteinTherapy 1 2 Gene Therapy 3 Cell Therapy
IV. EXPERIENCE IN PROTEIN THERAPY ,[object Object],[object Object],[object Object]
ย 
ย 
V. UPDATE IN GENE THERAPY ,[object Object],[object Object],[object Object],[object Object],[object Object]
Intramyocardial Injection Via Thoracotomy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Catheter-Based Transendocardial Injection ,[object Object],[object Object],[object Object],[object Object]
Intracoronary Delivery ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
VI. CELL THERAPY STUDIES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ย 
VII. NONINVASIVE IMAGING TECHNIQUES ,[object Object],[object Object],[object Object]
VIII. COLLATERAL-SENSITIVE MRI IN SWINE MODEL OF CHRONIC ISCHEMIA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IX. ELECTROMECHANICAL LV MAPPING/INJECTION SYSTEM ,[object Object],[object Object],[object Object],[object Object]
X. ANIMAL MODELS FOR ANGIOGENESIS:DEPENDABLE BASIS FOR HUMAN STUDIES? ,[object Object],[object Object],[object Object],[object Object],[object Object]
XI. CONCLUSIONS ,[object Object],[object Object],[object Object]
๊ฐ์‚ฌํ•ฉ๋‹ˆ๋‹ค . ,[object Object],[object Object],[object Object]

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  • 22. ์„ธ๊ฐ€์ง€ ์น˜๋ฃŒ์  ์ ‘๊ทผ๋ฒ• ProteinTherapy 1 2 Gene Therapy 3 Cell Therapy
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