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General Anesthetics
Presented BY
Muhammad Ashfaq
Thiamylal Sodium
 General anesthetic
 Ultra-Short acting barbiturate
 Complete anesthesia of short duration
 sodium;4,6-dioxo-5-pentan-2-yl-5-prop-
2-enyl-1H-pyrimidine-2-thiolate
Structure
Properties
 Chemical Formula: C12H17N2NaO2S
 Molecular Weight: 276.33 g/mol
 Metabolism: Hepatic
 Biological half life: 14.3 hrs
Uses
 General Anesthetic
 Sedation
 Hypnosis
 with acetaminophen or aspirin
 sedative
 relaxant
 tension
 headaches,
 migraines, and pain.
Ketamine
 General Anesthetic
 Rapid Acting
 Block NMDA receptors (receptors, N-methyl-D-aspartate)
 2-(2-chlorophenyl)-2-(methylamino)cyclohexanone
hydrochloride
 Chemical Formula: C13H17Cl2NO
 Molecular Weight: 274.19 g/mol
 Metabolism: Hepatic
 CYP3A4
 CYP2C9
Uses
 General anesthetic
 Sedative
 Spinal anesthesia
 Analgesic
 Depression

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Anesthetics.pptx