Amazon RDS is a fully managed database service provided by AWS that allows users to deploy and manage relational databases in the cloud. It supports popular database engines like MySQL, Oracle, SQL Server, and PostgreSQL. With Amazon RDS, users don't have to worry about database management tasks like backups, software patching, hardware provisioning and database setup. It provides features like replication, automated backups, and high availability. While Amazon RDS simplifies database management, users don't have root access and downtime may occur during maintenance activities.