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Submitted By –
Ajay Kumar Yadav
MSc.Zoology(previous)
Submitted To –
Mr. Rajneesh Mishra
HOD , Zoology
PANCREAS
INTRODUCTION:-
 The pancreas is an organ of the digestive system and
endocrine system of vertebrates.
 In humans, it is located in the abdomen behind the
stomach and functions as a gland.
 The pancreas is a mixed or heterocrine gland.
STRUCTURE:-
 Pancreatic tissue is present in
all vertebrates but its precise
form and arrangement varies
widely.
 In humans, its stretching from
behind the stomach to the left
upper abdomen near the
spleen.
 In adults, it is about 12-15 cm
long, lobulated, and salmon-
coloured in appearance.
DEVELOPMENT:-
 The pancreas forms during
development from 2 buds
that arise from duodenal part
of the foregut.
 Pancreatic development
begins with the formation of a
dorsal and ventral pancreatic
bud.
• Dorsal bud and ventral bud
joins with the foregut through a
duct.
• The dorsal pancreatic bud forms
the neck, body, and the tail part
of the developed pancreas.
• The ventral pancreatic bud
forms the head part of the
developed pancreas.
FUNCTIONS:-
 The pancreas is involved in blood sugar
control and metabolism within the body, and
also in the secretion of the substances that
help in digestion.
 Pancreas perform the following functions:-
1) Endocrine function
2) Exocrine function
EXOCRINE FUNCTION:-
 The pancreas contain exocrine glands that produce
enzymes important to digestion.
 These enzymes includes trypsin and chymotrypsin to
digest protein.
 Amylase for the digestion of the carbohydrates and lipase
to break down fats.
 The common bile duct originates in the liver and the gall
bladder and produces another important digestive juice
called Bile.
ENDOCRINE FUNCTION:-
 The endocrine component of
the pancreas consist of islet
cells that create and release
important hormones directly
to the blood stream.
 Two main hormones are
insulin and glucagon.
 Maintaining proper blood
sugar level is crucial to the
functioning of key organs
including the brain, liver and
kidney.
DISEASES OF THE PANCREAS:-
 Disorder affecting pancreas include pancreatitis ,
pancreatic cancer. Each disorder may exhibit different
symptoms and requires different treatments.
 PANCREATITIS:-
it is the inflammation of the
pancreas that occur when pancreatic enzyme
secretions build up and begin to digest the organ itself
. It can occur as acute painful attack lasting a matter of
days .
PANCREATIC CANCER:-
 Particularly the most common type is
Adenocarcinoma.
 Pancreatic cancer is rare in people
younger than 40 and the median age of
diagnosis is 71.
 25% of the cases are attributable to
tobbacco and smoking while only 5-
10% cases are linked to inherited genes.
DIABETES MELLITUS:-
• Diabetes mellitus type 1:-
It is chronic autoimmune
diseases in which the immune system attacks the
insulin secreating beta cells of the pancreas .
• Insulin is needed to keep blood sugar level within
optimal range and its lack can lead to high blood
sugar.
• Type 1 diabetes can occur at any age but most often
seem before age 40.
DIABETES MELLITUS TYPE 2:-
 It is the most common type diabetes .
 The cause for high blood sugar in this is the
combination of insulin resistance and impaired insulin
secreation.
 For this ,both the genetic and environmental factors
are responsible.
 TEXTBOOK
 www.slideshare.com
 WIKIPEDIA
AJAY YADAV ppt of panc..pptx

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AJAY YADAV ppt of panc..pptx

  • 1. Submitted By – Ajay Kumar Yadav MSc.Zoology(previous) Submitted To – Mr. Rajneesh Mishra HOD , Zoology PANCREAS
  • 2. INTRODUCTION:-  The pancreas is an organ of the digestive system and endocrine system of vertebrates.  In humans, it is located in the abdomen behind the stomach and functions as a gland.  The pancreas is a mixed or heterocrine gland.
  • 3. STRUCTURE:-  Pancreatic tissue is present in all vertebrates but its precise form and arrangement varies widely.  In humans, its stretching from behind the stomach to the left upper abdomen near the spleen.  In adults, it is about 12-15 cm long, lobulated, and salmon- coloured in appearance.
  • 4. DEVELOPMENT:-  The pancreas forms during development from 2 buds that arise from duodenal part of the foregut.  Pancreatic development begins with the formation of a dorsal and ventral pancreatic bud.
  • 5. • Dorsal bud and ventral bud joins with the foregut through a duct. • The dorsal pancreatic bud forms the neck, body, and the tail part of the developed pancreas. • The ventral pancreatic bud forms the head part of the developed pancreas.
  • 6. FUNCTIONS:-  The pancreas is involved in blood sugar control and metabolism within the body, and also in the secretion of the substances that help in digestion.  Pancreas perform the following functions:- 1) Endocrine function 2) Exocrine function
  • 7. EXOCRINE FUNCTION:-  The pancreas contain exocrine glands that produce enzymes important to digestion.  These enzymes includes trypsin and chymotrypsin to digest protein.  Amylase for the digestion of the carbohydrates and lipase to break down fats.  The common bile duct originates in the liver and the gall bladder and produces another important digestive juice called Bile.
  • 8. ENDOCRINE FUNCTION:-  The endocrine component of the pancreas consist of islet cells that create and release important hormones directly to the blood stream.  Two main hormones are insulin and glucagon.  Maintaining proper blood sugar level is crucial to the functioning of key organs including the brain, liver and kidney.
  • 9. DISEASES OF THE PANCREAS:-  Disorder affecting pancreas include pancreatitis , pancreatic cancer. Each disorder may exhibit different symptoms and requires different treatments.  PANCREATITIS:- it is the inflammation of the pancreas that occur when pancreatic enzyme secretions build up and begin to digest the organ itself . It can occur as acute painful attack lasting a matter of days .
  • 10. PANCREATIC CANCER:-  Particularly the most common type is Adenocarcinoma.  Pancreatic cancer is rare in people younger than 40 and the median age of diagnosis is 71.  25% of the cases are attributable to tobbacco and smoking while only 5- 10% cases are linked to inherited genes.
  • 11. DIABETES MELLITUS:- • Diabetes mellitus type 1:- It is chronic autoimmune diseases in which the immune system attacks the insulin secreating beta cells of the pancreas . • Insulin is needed to keep blood sugar level within optimal range and its lack can lead to high blood sugar. • Type 1 diabetes can occur at any age but most often seem before age 40.
  • 12. DIABETES MELLITUS TYPE 2:-  It is the most common type diabetes .  The cause for high blood sugar in this is the combination of insulin resistance and impaired insulin secreation.  For this ,both the genetic and environmental factors are responsible.