This document summarizes the global impact of AIDS, noting that it has killed over 60 million people since the beginning and is still infecting over 5 million new people each year. Africa has been disproportionately affected, with over 25 million people living with HIV/AIDS in 2005 alone. Some of the hardest hit countries include South Africa, Botswana, Zimbabwe and Kenya, where AIDS has become a major cause of death and has left millions of children orphaned. The epidemic continues to grow rapidly in many parts of the world without effective prevention and treatment efforts.