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According to the endosymbiotic hypothesis, an aerobic prokaryote precursor was engulfed by
another leading to some organelle formation. With this, gene transfer had to occur from the
precursor cell's nucleus to the host cell. A gene, Cox2, in some species, is found in the
mitochondrial DNA while in other species, is found in the nuclear DNA. The initial transcript of
the mitochondrial Cox2 gene is modified by RNA editing, where some specific cytosines are
changed to uracils. Why do you think this is significant and how might it allow you to discover
whether the informational intermediate in the transfer was DNA or RNA? 5 points

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