This document contains summaries of several scientific studies on various topics: - A study found that colour retention of sorghum was better at lower pH levels and identified chalcones as major heat degradation products at higher pH levels. - Another study evaluated a traditional herbal preparation called Jobelyn for its effects on anemia and CD4+ T-cell counts in HIV+ patients in Nigeria. - A third study examined the acute and short-term chronic toxicity profiles of the herbal product Jobelyn®, which is recommended for anemia management, through gross morphological and histopathological analysis.

1. About Scientific Studies

2. Major Heat
Degradation Products
Colour retention was better at pH 1–2 (70.2–
118%) than at pH 3–7 (39.0–86.8%). Chalcones
were identified as the major heat degradation
products at pH 3–7.

3. Biological Effects Of
Sorghum
Modulating modalities has potential for
reducing inflammation-induced immune
suppression. Sorghum-based foods, teas,
beers, and extracts are used in traditional
medicine, placing an importance on obtaining
an increased understanding of the biological
effects of sorghum

4. Traditional Herbal
Preparation
The purpose of this study was to evaluate a
traditional herbal preparation, Jobelyn, for its
effects on anemia and CD4 + T-cell counts in
human immunodeficiency virus–positive (HIV +
) patients in Nigeria.

5. Treatment Of Anaemia
Jubi Formula® is a herbal preparation made
from three medicinal herbs (Parquetina
nigrescens, Sorghum bicolor and Harungana
madagascariensis). It has been reported to
have been successfully used in the treatment of
anaemia & natural remedy for diabetes in
humans

6. Morphological &
Histopathological
Jobelyn® is a commercial herbal product
recommended for the management of anemia
related illnesses. Despite its wide use, there is
limited report on its toxicological profile. This
study examined the acute and shortterm
chronic toxicity profiles of the product with
emphasis on the LD50, gross morphological
and histopathological effects.

7. Chemically Defined
Haematinics
The haematological changes observed with
commercially available haematinics . Results
showed that AHF produced effects in
haemoglobin (Hb) and packed cell volume
(PCV) levels which are reasonably comparable
with the reference commercial and chemically
defined haematinics

8. Chronic Neurological
Disorder
Psychosis is a chronic neurological disorde and
it remains a major medical and social problem
in most African countries. Individuals with
psychotic illness in this region tend to seek help
from traditional medical practitioners

9. Anti-amnesic &
Antioxidant properties
This investigation provides evidence that
suggests that JB has anti-amnesic and
antioxidant properties. Although the present
data suggest that the anti-amnesic property of
JB might be related to its antioxidant activity,
more studies are necessary to clarify this
observation

10. Free-radical
Scavenging
Extracts of the herbs Sorghum bicolor, basil,
and thyme were tested for total flavonoid
content and Free-radical scavenging ability
using the Aluminum Chloride Method and
DPPH Free-Radical Scavenging assay,
respectively.

11. Public Health
Significance
Aggression is a violent behavior emitted
against another organism that may lead to its
harm or death and thus is of public health
significance, which necessitates the search for
agents with anti-aggressive property

12. Treatment Of
Rheumatoid Arthritis
Jobelyn® (JB) is an African sorghum-based
food supplement claimed to be efficacious for
the treatment of rheumatoid arthritis (RA).
Although in vitro studies confirmed its anti-
inflammatory property, no study had shown
the effect of JB using in vivo animal models of
inflammation

13. Analgesic & Anxiolytic
Potentials
This study presents the results of the
pharmacological evaluation of the analgesic
and anxiolytic potentials of Jobelyn®, a potent
antioxidant African herbal formulation, in mice.
The analgesic effect was assessed utilizing
acetic acidinduced writhing, tail immersion and
formalininduced paw licking pain models

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