This document provides 50 low- and no-cost tips for improving the energy efficiency of industrial refrigeration systems through optimizing operations and maintenance. As the largest energy consumers, refrigeration systems should be a major target for savings. The tips are organized into sections on evaporator opportunities, compressor opportunities, evaporative condenser opportunities, and more. Implementing the tips can help reduce energy costs with little to no capital investment through activities like cleaning coils, adjusting pressure regulators, solving compressor issues, and ensuring proper condenser operations. Safety precautions are recommended, as improper implementation could cause harm.