This document provides an annual report on 4-VA initiatives at James Madison University. 4-VA is a collaborative partnership between 5 Virginia universities that promotes inter-university collaboration. The report details several research projects funded through 4-VA mini-grants and scale-up grants at JMU, including projects on mapping the universe through radio telescope observations, understanding the structure of proteins involved in HIV prevention, analyzing antibiotic-resistant bacteria in streams, and integrating biomimicry into an engineering course. The collaborations have advanced research, provided students with unique opportunities, and benefited the Commonwealth of Virginia.