The document provides concise notes on heterocyclic compounds, specifically pyrazole, emphasizing its properties as a weak base and its role in pharmaceuticals. It mentions the usage of antipyine and celecoxib as anti-inflammatory drugs (NSAIDs) for pain reduction. Additionally, it briefly discusses the methods of preparation and reactions related to these compounds.

1. Heterocyclic compounds short notes for Pharmacy students
© Dr. Atul R. Bendale4
heterocycliclecturenotes|
Pyrazole:
Aromatic, Pyrazole is a weak base, with pKb 11.5
ESR at 4 position (when substituted)
Antipyine is anti-inflammatory
drug (NSAID). Use to reduce the
pain.
Celecoxib is anti-inflammatory
drug (NSAID). Use to reduce the
pain.
Method of preparation
Reaction