4 dutura poisoning
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Dutura poisoning can occur when the plant is used to stupefy travelers. Symptoms include dizziness, delirium, drowsiness, dilated pupils, dimmed vision, dry mouth, slurred speech, difficulty swallowing, dry skin, fever, nausea, vomiting, distended bladder, inability to urinate, unsteady gait, and muscle spasms that can lead to stupor, seizures, and coma. Treatment involves immediate hospitalization, clearing the airway, washing the stomach, injections of diazepam and physostigmine or pilocarpine, supportive care like cold compresses for fever, nutrition via feeding tube, and maintaining fluid and electrolyte balance.
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7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
share - Lions, tigers, AI and health misinformation, oh my!.pptx
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There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
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We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
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4 dutura poisoning
- 2. DUTURA POISONING Medicolegal use: To stupefy travelers in railway station, bus terminal, in train or bus.
- 3. DUTURA POISONING Clinical feature: Dizziness Delirium Drowsiness Dilated pupil Dimness of vision Dryness of mouth Dysarthria Dysphagia
- 4. DUTURA POISONING Clinical feature: Dry skin, hyperpyrexia Nausea, vomiting Distended bladder, retention of urine Staggering gait, pill rolling movement Stupor, convulsion, coma
- 5. DUTURA POISONING Investigation: CBC RFT Serum electrolytes
- 6. DUTURA POISONING Management: Immediate hospitalisation Clearance of airway Stomach wash with weak sol of KMnO4 Inj diazepam 10 mg i/m stat Injphysostigmine or pilocarpine 1-4 mg in adult
- 7. DUTURA POISONING Management: Supportive and symptomatic treatment- Cold sponging for hyperpyrexia Maintenance of nutrition by nasogastric feeding Fluid and electrolytes balance