The June 2022 Patch Tuesday webinar highlights 16 Microsoft updates, including critical OS updates addressing significant vulnerabilities like CVE-2022-30136 and the Follina vulnerability (CVE-2022-30190). Key discussions include the second phase of the DCOM server security update and guidance for managing the end-of-life transition for Windows 10 and Internet Explorer 11. Notable issues and update impacts are also detailed, emphasizing required restarts and specific workarounds for affected systems.