The document discusses the benefits of walking meetings and moving while working. It provides details on installing a "walking meeting room" to facilitate walking meetings. It also summarizes the unveiling of a statue in Washington D.C. of former mayor Marion Barry, capturing his dedication to empowering disadvantaged communities. Strategies are suggested for effective walking meetings, such as planning a route and embracing curiosity during the walk. Rotating leadership and getting to know each other through short introductions are proposed ideas for the group.
Three-S Network Series kembali hadir dengan mengangkat tema “People, Technology, and Society”, sebagai wadah untuk berbagi, berdiskusi, berjejaring dan berkolaborasi.
Melalui ‘People, Technology, and Society Series” ini kita akan belajar keterampilan untuk memahami mengenai manusia dan interaksinya dengan teknologi serta lingkungan agar dapat menggunakan pengetahuan tersebut untuk merancang produk, program, aktivitas dalam mencapai target yang ditetapkan.
Group of slides related to metabolic health, low carbohydrate diets, low carbon diets, the "sustainable diet" and epidemiologic trends shaping the health of our nation.
Second re-submission, 3rd submission total, to Unicode for inclusion in the 2020 Unicode standard, March, 2019, updated March 12, 2019 with additional requested footnote, not reflected in this version (slideshare doesn't allow re-uploads anymore)
Proposal for new valid emoji sequence: Transgender Flag: version 4 for 2019Ted Eytan, MD, MS, MPH
The following is a proposal to the Unicode Consortium for a SWJ sequence, to be recommended for general interchange (RGI). The Transgender Flag would complement the Rainbow Flag as a representation of non-cis gender identities and intersex people. Submitted to the Unicode consortium, March, 2018, for inclusion in the 2019 standard.
2018.02.22 Designing Healthy and Safe Health Care Spaces for LGBTQ PeopleTed Eytan, MD, MS, MPH
Presentation for LGBTQ health series for Kaiser Permanente physicians, nurses, staff, on designing healthy and safe health care facilities for all humans.
Proposal for new valid emoji sequence: Transgender Symbols and Pride FlagTed Eytan, MD, MS, MPH
Version 3, Proposal to Unicode Consortium for Transgender symbol inclusion in 2018 emoji character set. Detailed technical specification included this time.
Three-S Network Series kembali hadir dengan mengangkat tema “People, Technology, and Society”, sebagai wadah untuk berbagi, berdiskusi, berjejaring dan berkolaborasi.
Melalui ‘People, Technology, and Society Series” ini kita akan belajar keterampilan untuk memahami mengenai manusia dan interaksinya dengan teknologi serta lingkungan agar dapat menggunakan pengetahuan tersebut untuk merancang produk, program, aktivitas dalam mencapai target yang ditetapkan.
Group of slides related to metabolic health, low carbohydrate diets, low carbon diets, the "sustainable diet" and epidemiologic trends shaping the health of our nation.
Second re-submission, 3rd submission total, to Unicode for inclusion in the 2020 Unicode standard, March, 2019, updated March 12, 2019 with additional requested footnote, not reflected in this version (slideshare doesn't allow re-uploads anymore)
Proposal for new valid emoji sequence: Transgender Flag: version 4 for 2019Ted Eytan, MD, MS, MPH
The following is a proposal to the Unicode Consortium for a SWJ sequence, to be recommended for general interchange (RGI). The Transgender Flag would complement the Rainbow Flag as a representation of non-cis gender identities and intersex people. Submitted to the Unicode consortium, March, 2018, for inclusion in the 2019 standard.
2018.02.22 Designing Healthy and Safe Health Care Spaces for LGBTQ PeopleTed Eytan, MD, MS, MPH
Presentation for LGBTQ health series for Kaiser Permanente physicians, nurses, staff, on designing healthy and safe health care facilities for all humans.
Proposal for new valid emoji sequence: Transgender Symbols and Pride FlagTed Eytan, MD, MS, MPH
Version 3, Proposal to Unicode Consortium for Transgender symbol inclusion in 2018 emoji character set. Detailed technical specification included this time.
2016.11.17 Walking at Work: The What, Why & How of Walking MeetingsTed Eytan, MD, MS, MPH
Presentation given with AmericaWalks on November 17, 2016
"Walking is a great way to incorporate more physical activity into your daily routine. One way to make sure you are getting the recommended amount of steps is to turn meetings at work into walking meetings. This webinar explores the what, why and how of walking meetings and learn from examples of businesses and organization that have put them into practice. - See more at: http://americawalks.org/walking-at-work-the-what-why-how-of-walking-meetings-november-17-2016-webinar/#sthash.V97AwZMP.dpuf"
Update of presentation on using social media as a health professional, given to the students of the Kaiser Permanente School of Allied Health Sciences, Richmond, CA, USA
KP in DC : Quest for Total Health (Center for Total Health Overview)Ted Eytan, MD, MS, MPH
Presentation given by myself and Keith Montgomery, Executive Director, about the Kaiser Permanente Center for Total Health to Kaiser Permanente colleagues, December 10, 2015
Presentation to Kaiser Permanente Government Relations Workshop November 6, 2015, Pasadena California, covering the Kaiser Permanente Center for Total Health, Social Innovation, and the KPLantern Project.
"Resilient people and companies face reality with staunchness, make meaning of hardship instead of crying out in despair, and improvise solutions from thin air. Others do not. This is the nature of resilience, and we will never completely understand it" - Harvard Business Review 2002
Presentation given to the Professional Convention Management Association - Capital Chapter, Washington, DC, as part of a program on hosting healthy meetings, at the Kaiser Permanente Center for Total Health
Intro to Kaiser Permanente Center for Total Health and Social InnovationTed Eytan, MD, MS, MPH
The Center for Total Health is Kaiser Permanente's Social Innovation Center. This presentation was given to the American College of Preventive Medicine Corporate Roundtable, meeting in Washington, DC, to introduce the Center, Social Innovation, and Total Health for individuals and communities. Thanks for having me!
Total Health, Being a Transgender ally and Unconscious bias HLTH 471 - univ...Ted Eytan, MD, MS, MPH
Presentation to HLTH 471 - Women's Health - at University of Maryland, Shady Grove, with faculty Sabrina Matoff-Stepp, PhD., on the social determinants of health for transgender individuals and transgender women specifically + a view into the Kaiser Permanente Center for Total Health, in Washington, DC USA
Presentation at Transportation Techies, August 20, 2015, at Walk Hack Night on the work of the Kaiser Permanente Center for Total Health to install and analyze data from multiple population sensors, including ones using infrared and computed video technology.
Population sensors have great promise to promote physical activity compared to wearable devices, which can be expensive, impact privacy, and have low uptake and use.
Total Health and Innovation: Demystifying Medicare 2015 Summer AcademyTed Eytan, MD, MS, MPH
Presentation at the Kaiser Family Foundation, Washington, DC USA, National Academy of Social Insurance, in collaboration with the Alliance of Community Health Plans
Walls, Ceilings, Closet Doors (Things Worth Shattering): Total Health and Soc...Ted Eytan, MD, MS, MPH
2015 Update on the Kaiser Permanente Center for Total Health, the Social Innovation Center of Kaiser Permanente, including examples of social movements and interventions that have been born or amplified since 2011.
7 Minute "Shift and Share" Presentation given at "Strength Beyond our Walls" event with RWJF Nurse Executive Fellows, showing the example of a vulnerable population (people who are transgender or gender non-conforming) and hidden strengths (transformational leadership and compassion and acceptance for others)
Presentation to the 2015 LGBTQ Health Care Speaker Series for knowledgeable providers - Kaiser Permanente. Given from the Kaiser Permanente Center for Total Health, Washington, DC USA
On December 10, 2014, The Kaiser Permanente Center for Total Health and National Center for Transgender Equality are hosting a Community Clinician Roundtable for providers who care for transgender patients in the Washington, DC, MD, VA community. The roundtable will include physicians, nurses, therapists, attorneys, and health care staff who support this population.
#transformKP: Total Health and Social Innovation (for Labor Management Partne...Ted Eytan, MD, MS, MPH
Presentation given to the Kaiser Permanente Labor Management Partnership all hands meeting, December 2, 2014, in San Francisco, California. "The Labor Management Partnership (LMP) is the largest and longest-lasting partnership of its kind in the country. Created in 1997, it is based on a series of agreements between the Coalition of Kaiser Permanente Unions, made up of 27 union locals, Kaiser Permanente and the Permanente medical groups in each region. Today, it covers almost 100,000 union members and tens of thousands of managers and physicians."
Introduction to a panel of architects, public heath professionals, and civic leaders about designing for health. Hosted by American Institute of Architects, Washington, DC, on October 8, 2014
Creating the case for involving members (patients) at the organizational and governance level of the health system. Given for the Kaiser Permanente Digital Workforce Group who now include a member on their Executive Governance Group.
Health is the new HIT - Stanford Biomedical Informatics 207 | July 31 2014Ted Eytan, MD, MS, MPH
Using technology to enable a health system that supports total health and makes lives better. Kaiser Permanente Center for Total Health / guest lecture at Stanford School of Medicine : Digital Medicine: Designing IT Innovations that Improve Healthcare
Stanford University Biomedical Informatics 207
Summer Quarter 2014
Keynote, 2nd annual Kaiser Permanente LGBTQI Health Symposium. About unconscious/implicit bias, in the setting of transgender person health. Sheraton Universal, Universal City, California
Keshav Tyagi - MPHc Protecting the Health of the Transgender PopulationTed Eytan, MD, MS, MPH
"The Need for a Non-Discrimination Statement to Protect the Health of the Transgender Population in the State of Massachussetts," by Keshav Tyagi, Keck School of Medicine, University of Southern California, Master of Public Health Program
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
2016.11.17 Walking at Work: The What, Why & How of Walking MeetingsTed Eytan, MD, MS, MPH
Presentation given with AmericaWalks on November 17, 2016
"Walking is a great way to incorporate more physical activity into your daily routine. One way to make sure you are getting the recommended amount of steps is to turn meetings at work into walking meetings. This webinar explores the what, why and how of walking meetings and learn from examples of businesses and organization that have put them into practice. - See more at: http://americawalks.org/walking-at-work-the-what-why-how-of-walking-meetings-november-17-2016-webinar/#sthash.V97AwZMP.dpuf"
Update of presentation on using social media as a health professional, given to the students of the Kaiser Permanente School of Allied Health Sciences, Richmond, CA, USA
KP in DC : Quest for Total Health (Center for Total Health Overview)Ted Eytan, MD, MS, MPH
Presentation given by myself and Keith Montgomery, Executive Director, about the Kaiser Permanente Center for Total Health to Kaiser Permanente colleagues, December 10, 2015
Presentation to Kaiser Permanente Government Relations Workshop November 6, 2015, Pasadena California, covering the Kaiser Permanente Center for Total Health, Social Innovation, and the KPLantern Project.
"Resilient people and companies face reality with staunchness, make meaning of hardship instead of crying out in despair, and improvise solutions from thin air. Others do not. This is the nature of resilience, and we will never completely understand it" - Harvard Business Review 2002
Presentation given to the Professional Convention Management Association - Capital Chapter, Washington, DC, as part of a program on hosting healthy meetings, at the Kaiser Permanente Center for Total Health
Intro to Kaiser Permanente Center for Total Health and Social InnovationTed Eytan, MD, MS, MPH
The Center for Total Health is Kaiser Permanente's Social Innovation Center. This presentation was given to the American College of Preventive Medicine Corporate Roundtable, meeting in Washington, DC, to introduce the Center, Social Innovation, and Total Health for individuals and communities. Thanks for having me!
Total Health, Being a Transgender ally and Unconscious bias HLTH 471 - univ...Ted Eytan, MD, MS, MPH
Presentation to HLTH 471 - Women's Health - at University of Maryland, Shady Grove, with faculty Sabrina Matoff-Stepp, PhD., on the social determinants of health for transgender individuals and transgender women specifically + a view into the Kaiser Permanente Center for Total Health, in Washington, DC USA
Presentation at Transportation Techies, August 20, 2015, at Walk Hack Night on the work of the Kaiser Permanente Center for Total Health to install and analyze data from multiple population sensors, including ones using infrared and computed video technology.
Population sensors have great promise to promote physical activity compared to wearable devices, which can be expensive, impact privacy, and have low uptake and use.
Total Health and Innovation: Demystifying Medicare 2015 Summer AcademyTed Eytan, MD, MS, MPH
Presentation at the Kaiser Family Foundation, Washington, DC USA, National Academy of Social Insurance, in collaboration with the Alliance of Community Health Plans
Walls, Ceilings, Closet Doors (Things Worth Shattering): Total Health and Soc...Ted Eytan, MD, MS, MPH
2015 Update on the Kaiser Permanente Center for Total Health, the Social Innovation Center of Kaiser Permanente, including examples of social movements and interventions that have been born or amplified since 2011.
7 Minute "Shift and Share" Presentation given at "Strength Beyond our Walls" event with RWJF Nurse Executive Fellows, showing the example of a vulnerable population (people who are transgender or gender non-conforming) and hidden strengths (transformational leadership and compassion and acceptance for others)
Presentation to the 2015 LGBTQ Health Care Speaker Series for knowledgeable providers - Kaiser Permanente. Given from the Kaiser Permanente Center for Total Health, Washington, DC USA
On December 10, 2014, The Kaiser Permanente Center for Total Health and National Center for Transgender Equality are hosting a Community Clinician Roundtable for providers who care for transgender patients in the Washington, DC, MD, VA community. The roundtable will include physicians, nurses, therapists, attorneys, and health care staff who support this population.
#transformKP: Total Health and Social Innovation (for Labor Management Partne...Ted Eytan, MD, MS, MPH
Presentation given to the Kaiser Permanente Labor Management Partnership all hands meeting, December 2, 2014, in San Francisco, California. "The Labor Management Partnership (LMP) is the largest and longest-lasting partnership of its kind in the country. Created in 1997, it is based on a series of agreements between the Coalition of Kaiser Permanente Unions, made up of 27 union locals, Kaiser Permanente and the Permanente medical groups in each region. Today, it covers almost 100,000 union members and tens of thousands of managers and physicians."
Introduction to a panel of architects, public heath professionals, and civic leaders about designing for health. Hosted by American Institute of Architects, Washington, DC, on October 8, 2014
Creating the case for involving members (patients) at the organizational and governance level of the health system. Given for the Kaiser Permanente Digital Workforce Group who now include a member on their Executive Governance Group.
Health is the new HIT - Stanford Biomedical Informatics 207 | July 31 2014Ted Eytan, MD, MS, MPH
Using technology to enable a health system that supports total health and makes lives better. Kaiser Permanente Center for Total Health / guest lecture at Stanford School of Medicine : Digital Medicine: Designing IT Innovations that Improve Healthcare
Stanford University Biomedical Informatics 207
Summer Quarter 2014
Keynote, 2nd annual Kaiser Permanente LGBTQI Health Symposium. About unconscious/implicit bias, in the setting of transgender person health. Sheraton Universal, Universal City, California
Keshav Tyagi - MPHc Protecting the Health of the Transgender PopulationTed Eytan, MD, MS, MPH
"The Need for a Non-Discrimination Statement to Protect the Health of the Transgender Population in the State of Massachussetts," by Keshav Tyagi, Keck School of Medicine, University of Southern California, Master of Public Health Program
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
3. Best App Ever: Human Brain
3
activated
activated
activated
deactivate
it works bettertm
Source: Hillman CH, Erickson KI, Kramer AF. Be smart, exercise your heart: exercise effects
on brain and cognition. Nature Reviews. Neuroscience. 2008;9(1):58–65..
Slide created by Ted Eytan, MD | @tedeytan | December, 2012
4. 4
It just works better™
Source: Hillman CH, Erickson KI, Kramer AF. Be smart, exercise your heart: exercise effects on brain and cognition.
Nature Reviews. Neuroscience. 2008;9(1):58–65..
Slide created by Ted Eytan, MD | @tedeytan | December, 2012
6. Today
6
• The piece, by
Washington area
sculptor Steven
Weitzman, will be one
of three full-body
statues in the city of
African Americans
• "I wanted to capture
the accessibility," he
says. "This is a man
who dedicated his
whole life to try to bring
up and give
opportunities to those
who have been
traditionally kept down
in our society.”
Sources: https://www.washingtonpost.com/local/social-issues/still-bigger-than-life-dc-unveils-bronze-statue-of-former-mayor-marion-barry/
2018/03/03/d77dfd60-1eee-11e8-9de1-147dd2df3829_story.html; https://www.washingtonpost.com/lifestyle/style/after-dc-chose-a-white-artist-
for-marion-barrys-statue-an-unlikely-friendship-was-forged/2018/02/01/553a582c-05ca-11e8-94e8-e8b8600ade23_story.html
7. Walking Meeting Checklist
• Ask Permission
• Check for shoes & mobility issues
• Plan your route (by time or distance)
• Handy site: plotaroute.com
• Embrace curiosity as you walk
7
8. Ideas for this Group
• Rotate leadership with a short pitch
• Who are you? Why are you here?
• Round robin short intros
• Single word describing __________
• Walk to a local monument (there are many)
• Can switch around at ½ way mark
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