Putting Cracks in the Paywall: Connecting Librarian Values, Actions, and Tech...Robyn Hall
A core value of librarianship lies in providing users with equal and immediate access to information. This is frequently not possible, however, particularly when it concerns providing access to academic research literature available through costly journal subscriptions. Drawing on a range of examples, this presentation describes individual and collective actions that librarians have taken to overcome commercial barriers and help to ensure equitable online access to research and scholarship. It also addresses initiatives and services that both academic and public libraries could be implementing and more broadly supporting if unrestricted access to information is truly a goal. Participants will be asked to consider their own perspectives on the open access movement, its intentions and limitations, and how they might support it in their own professional lives.
Putting Cracks in the Paywall: Connecting Librarian Values, Actions, and Tech...Robyn Hall
A core value of librarianship lies in providing users with equal and immediate access to information. This is frequently not possible, however, particularly when it concerns providing access to academic research literature available through costly journal subscriptions. Drawing on a range of examples, this presentation describes individual and collective actions that librarians have taken to overcome commercial barriers and help to ensure equitable online access to research and scholarship. It also addresses initiatives and services that both academic and public libraries could be implementing and more broadly supporting if unrestricted access to information is truly a goal. Participants will be asked to consider their own perspectives on the open access movement, its intentions and limitations, and how they might support it in their own professional lives.
Environmental Education and Gifted Learnersgjducamp
This presentation was given at the 2010 NCAGT Conference. It shares resources and the necessity for teaching Environmental Education to Gifted Students.
Sustaining research software at the Apache Software Foundation
Presented at BOSC 2015, Dublin on 2015-07-11. http://www.open-bio.org/wiki/BOSC_2015
Source: http://slides.com/soilandreyes/20150611-bosc2015-apache
Presented 2014-10-30 at Taverna Open Development Workshop in Manchester http://dev.mygrid.org.uk/wiki/display/developer/Taverna+Open+Development+Workshop
Also available at http://slides.com/soilandreyes/2014-10-31-taverna-3-architecture#/
2014-10-30 Taverna 3 status
Presented at Taverna Open Development Workshop 2014 in Manchester.
http://dev.mygrid.org.uk/wiki/display/developer/Taverna+Open+Development+Workshop#TavernaOpenDevelopmentWorkshop-Day1-Thursday2014-10-30
Taverna is becoming an Apache Incubator project. What are the effects on Taverna as an open source project and its future development?
HTML version: http://slides.com/soilandreyes/2014-10-30-taverna-incubator/
Wiki version: http://dev.mygrid.org.uk/wiki/display/developer/Taverna+as+an+Apache+Incubator+project
Presented 2014-10-30 at Taverna Open Development Workshop http://dev.mygrid.org.uk/wiki/display/developer/Taverna+Open+Development+Workshop
OMEX Combine Archives as example of Research Object in the wild - how converting it to RO Bundles using http://dx.doi.org/10.5281/zenodo.10439
Source pptx:
https://onedrive.live.com/view.aspx?cid=37935FEEE4DF1087&resid=37935FEEE4DF1087!788&app=PowerPoint%20f
2013-07-19 myExperiment research objects, beyond workflows and packs (PPTX)Stian Soiland-Reyes
Presentation at BOSC 2013 / ISMB 2013. (PowerPoint 2013 source)
PDF: https://www.slideshare.net/soilandreyes/2013-0719bosc-2013myexperimentresearchobjectsslides
See also poster at http://www.slideshare.net/soilandreyes/2013-0718bosc-2013myexperimentresearchobjectsposter-24242509 or
submitted abstract: https://docs.google.com/document/d/1jaAuPV-EnbsyI14L56HKHBQP7eDVfeXGLlK-LwohnWw/edit?usp=sharing
We have evolved Research Objects as a mechanism to preserve digital resources related to research, by providing mechanisms, formats and architecture for describing aggregated resources (hypothesis, workflow, datasets, scripts, services), their relations (is input for, explains, used by), provenance (graph was derived from dataset A, B and C) and attribution (who contributed what, and when?).
The website myExperiment is already popular for collaborating on, publishing and sharing scientific workflows, however we have found that for understanding and preserving a workflow over time, its definition is not enough, specially faced with workflow decay, services and tools that change over time. We have therefore adapted the research object model as a foundation for the myExperiment packs, allowing uploading of workflow runs, inputs, outputs and other files relevant to the workflow, relating them with annotations and integrated the Wf4Ever architecture for performing decay analysis and tracking a research object’s evolution as it and its constituent resources change over time.
Open Annotation Rollout, Manchester, 2013-06-25
See also PPTX version with Notes: http://www.slideshare.net/soilandreyes/2013-0624annotatingr-osopenannotationmeeting
Open Annotation Rollout, Manchester, 2013-06-25
See also PDF version: http://www.slideshare.net/soilandreyes/2013-0624annotatingr-osopenannotationmeeting-23289491
Slide deck presenting the Provenance support of Taverna workflow system, detailing architecture, ontologies and how results are exported as Research Object bundles, including the PROV-O provenance of the workflow run.
This upload is the PDF version, for PPTX source, see https://www.slideshare.net/soilandreyes/20130529-taverna-provenance-pptx-source/
Environmental Education and Gifted Learnersgjducamp
This presentation was given at the 2010 NCAGT Conference. It shares resources and the necessity for teaching Environmental Education to Gifted Students.
Sustaining research software at the Apache Software Foundation
Presented at BOSC 2015, Dublin on 2015-07-11. http://www.open-bio.org/wiki/BOSC_2015
Source: http://slides.com/soilandreyes/20150611-bosc2015-apache
Presented 2014-10-30 at Taverna Open Development Workshop in Manchester http://dev.mygrid.org.uk/wiki/display/developer/Taverna+Open+Development+Workshop
Also available at http://slides.com/soilandreyes/2014-10-31-taverna-3-architecture#/
2014-10-30 Taverna 3 status
Presented at Taverna Open Development Workshop 2014 in Manchester.
http://dev.mygrid.org.uk/wiki/display/developer/Taverna+Open+Development+Workshop#TavernaOpenDevelopmentWorkshop-Day1-Thursday2014-10-30
Taverna is becoming an Apache Incubator project. What are the effects on Taverna as an open source project and its future development?
HTML version: http://slides.com/soilandreyes/2014-10-30-taverna-incubator/
Wiki version: http://dev.mygrid.org.uk/wiki/display/developer/Taverna+as+an+Apache+Incubator+project
Presented 2014-10-30 at Taverna Open Development Workshop http://dev.mygrid.org.uk/wiki/display/developer/Taverna+Open+Development+Workshop
OMEX Combine Archives as example of Research Object in the wild - how converting it to RO Bundles using http://dx.doi.org/10.5281/zenodo.10439
Source pptx:
https://onedrive.live.com/view.aspx?cid=37935FEEE4DF1087&resid=37935FEEE4DF1087!788&app=PowerPoint%20f
2013-07-19 myExperiment research objects, beyond workflows and packs (PPTX)Stian Soiland-Reyes
Presentation at BOSC 2013 / ISMB 2013. (PowerPoint 2013 source)
PDF: https://www.slideshare.net/soilandreyes/2013-0719bosc-2013myexperimentresearchobjectsslides
See also poster at http://www.slideshare.net/soilandreyes/2013-0718bosc-2013myexperimentresearchobjectsposter-24242509 or
submitted abstract: https://docs.google.com/document/d/1jaAuPV-EnbsyI14L56HKHBQP7eDVfeXGLlK-LwohnWw/edit?usp=sharing
We have evolved Research Objects as a mechanism to preserve digital resources related to research, by providing mechanisms, formats and architecture for describing aggregated resources (hypothesis, workflow, datasets, scripts, services), their relations (is input for, explains, used by), provenance (graph was derived from dataset A, B and C) and attribution (who contributed what, and when?).
The website myExperiment is already popular for collaborating on, publishing and sharing scientific workflows, however we have found that for understanding and preserving a workflow over time, its definition is not enough, specially faced with workflow decay, services and tools that change over time. We have therefore adapted the research object model as a foundation for the myExperiment packs, allowing uploading of workflow runs, inputs, outputs and other files relevant to the workflow, relating them with annotations and integrated the Wf4Ever architecture for performing decay analysis and tracking a research object’s evolution as it and its constituent resources change over time.
Open Annotation Rollout, Manchester, 2013-06-25
See also PPTX version with Notes: http://www.slideshare.net/soilandreyes/2013-0624annotatingr-osopenannotationmeeting
Open Annotation Rollout, Manchester, 2013-06-25
See also PDF version: http://www.slideshare.net/soilandreyes/2013-0624annotatingr-osopenannotationmeeting-23289491
Slide deck presenting the Provenance support of Taverna workflow system, detailing architecture, ontologies and how results are exported as Research Object bundles, including the PROV-O provenance of the workflow run.
This upload is the PDF version, for PPTX source, see https://www.slideshare.net/soilandreyes/20130529-taverna-provenance-pptx-source/
At "Metagenomics, metagenetics and Pylogenetic workflows for Ocean Sampling Day" Workshop
Max Planck Institute for Marine Microbiology, Bremen, Germany 2013-03-21
For PPTX source - download http://www.wf4ever-project.org/wiki/download/attachments/2064544/2013-03-21-OSD-Bremen-Stian-What+can+provenance+do+for+me.pptx
2012 03-28 Wf4ever, preserving workflows as digital research objectsStian Soiland-Reyes
Presented on 2012-03-28 at EGI Community Forum 2012, Munich.
http://www.wf4ever-project.org/
http://purl.org/wf4ever/model
http://cf2012.egi.eu/
https://www.egi.eu/indico/sessionDisplay.py?sessionId=66&confId=679#20120328
2011 07-06 SCUFL2 Poster - because a workflow is more than its definition (BO...Stian Soiland-Reyes
See presentation at http://www.slideshare.net/soilandreyes/2011-0716-scufl2-because-a-workflow-is-more-than-its-definition-bosc-2011
From BOSC 2011 - http://www.open-bio.org/wiki/BOSC_2011_Schedule
Presentation of Taverna from UKOLN DevSci "Workflow Tools" event in Bath, 2010-11-30
PDF version: http://www.slideshare.net/soilandreyes/taverna-workflow-management-system-2010-1130-bath-workflow-tools
http://taverna.org.uk/
http://www.ukoln.ac.uk/events/devcsi/workflow_tools/programme/index.html
http://devcsi.ukoln.ac.uk/
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Scholarly HTML is an early initiative to formalize which HTML elements should be used for scholarly articles. It has a community group, but activity has stalled in recent years.
RASH is another attempt to formalize which HTML elements – and in which combinations - are recommended for writing academic articles. CSS can be applied for traditional 1960 ALGOL-60-look of your paper, even if it is on the web.
Dokieli is a web-based editor for academic articles, with support for decentralized annotations (using W3C Web Annotation Model) and notifications (Using W3) Linked Data Notifications). This example also shows how to by-pass the traditional publishing limitations – include a hyperlink to the live HTML paper in the abstract. (you could even by-pass paywalls like that..although this paper is Gold Open Access at Springer).
With a click on the tool icon you can “fork” the article and edit it further, saved at your own location, or add annotations and reviews.
Linked Research is an initiative to by-pass traditional publishers all together. This is taking the preprint idea further – just publish your paper anywhere on the web, and notify the Linked Research Inbox to solicit distributed reviews of your article. It encourages using HTML to the fullest – no restrictions on elements, you can embed live data, animations and web applications. While using dokie.li helps with the authoring side, hosting is up to each author. This raises many questions to future preservation, availability, neutrality, dependencies (embedded content), citations, identity and versioning – overlapping with the concerns we identified for Research Objects.
A very lively discussion about these different approaches emerged last month on the scholarly-html mailing list – bring out the popcorn and follow the different opinions!
Let’s not forget the oldies – ePub is a standardized eBook format, basically a zip file with manifest and a bunch of HTML pages (e.g. one per chapter). Their archive actually is the basis for our Research Object Bundle.
ePub lives on in the recently started Digital Publishing Working Group at W3C