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2013-05-22 Atul Butte's presentation at the Big Data in BioMedicine Conference

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University of California, San Francisco
University of California, San Francisco

Atul Butte's presentation at the Big Data in BioMedicine Conference 2013-05-22 Atul

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Kilo Mega Giga Tera Peta Exa Zetta
Total 1.2 million microarrays available Doubles every 2-3 years Butte AJ. Translational Bioinformatics: coming of age. JAMIA, 2008.
~300 Diseases and Conditions 20k+ Genes Blue: gene goes down in disease Yellow: gene goes up in disease Human Disease Gene Expression Collection Butte AJ, Kohane IS. Nature Biotechnology, 2006, 24:55. Butte AJ, Chen R. Proc AMIA Fall Symposium, 2006. Chen R, Butte AJ. Nature Methods, 2007. Dudley J, Tibshirani R, Deshpande T, Butte AJ. Molecular Systems Biology, 2009. Shen-Orr S, ... Davis MM, Butte AJ. Nature Methods, 2010. Joel Dudley
Lamb J, ..., Golub TR. Science, 2006. Sirota M, Dudley JT, ..., Sweet-Cordero A, Sage J, Butte AJ. Science Translational Medicine, 2011. Marina Sirota Joel Dudley
Rat colonoscopy Rat with Inflammatory Bowel Disease Inflammatory Bowel Disease After Anti-seizure Drug Dudley JT, Sirota M, ..., Pasricha J, Butte AJ. Science Translational Medicine, 2011. Anti-seizure drug works against a rat model of inflammatory bowel disease
Data-driven Systems Medicine
What next? Let’s figure that out together!
Thanks • Kristin Goldthorpe • Michelle Christierson • Priya Singh • Michele Schiele and Ted Tussing • Carlos Bustamante, Euan Ashley, Russ Altman, Alan Yeung, Phil Lavori • All our helpers and volunteers • Phil Pizzo • Lloyd Minor • John Bell • Li Ka Shing Foundation
2013-05-22 Atul Butte's presentation at the Big Data in BioMedicine Conference

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2013-05-22 Atul Butte's presentation at the Big Data in BioMedicine Conference

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  • 6. Total 1.2 million microarrays available Doubles every 2-3 years Butte AJ. Translational Bioinformatics: coming of age. JAMIA, 2008.
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  • 9. ~300 Diseases and Conditions 20k+ Genes Blue: gene goes down in disease Yellow: gene goes up in disease Human Disease Gene Expression Collection Butte AJ, Kohane IS. Nature Biotechnology, 2006, 24:55. Butte AJ, Chen R. Proc AMIA Fall Symposium, 2006. Chen R, Butte AJ. Nature Methods, 2007. Dudley J, Tibshirani R, Deshpande T, Butte AJ. Molecular Systems Biology, 2009. Shen-Orr S, ... Davis MM, Butte AJ. Nature Methods, 2010. Joel Dudley
  • 10. Lamb J, ..., Golub TR. Science, 2006. Sirota M, Dudley JT, ..., Sweet-Cordero A, Sage J, Butte AJ. Science Translational Medicine, 2011. Marina Sirota Joel Dudley
  • 11. Rat colonoscopy Rat with Inflammatory Bowel Disease Inflammatory Bowel Disease After Anti-seizure Drug Dudley JT, Sirota M, ..., Pasricha J, Butte AJ. Science Translational Medicine, 2011. Anti-seizure drug works against a rat model of inflammatory bowel disease
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  • 23. What next? Let’s figure that out together!
  • 24. Thanks • Kristin Goldthorpe • Michelle Christierson • Priya Singh • Michele Schiele and Ted Tussing • Carlos Bustamante, Euan Ashley, Russ Altman, Alan Yeung, Phil Lavori • All our helpers and volunteers • Phil Pizzo • Lloyd Minor • John Bell • Li Ka Shing Foundation