Company presentation on NovioSys by Jaroslav Jansa as presented during the SMB meeting on June 30, 2016 in Nijmegen.

1. NovioSys, B.V.
NovioSys, B.V. | Transistorweg 5 | 6534 AT Nijmegen | The Netherlands |
www.noviosys.com

2. The Company
NovioSys, B.V. is a Dutch start-up company founded in 2015 in
order to transfer know-how from the development of
telemedicine products during more than 10 years in the Czech
Republic, into the international science and technology center
NovioTechCampus , Nijmegen. The main products are:
HealthAnalyst – biomedical data mining system
MacTrack – RFID localization and communication system
PrenCare – system for monitoring risk pregnant women
4.7.2016

3. NovioSys, B.V. Products
PrenCare –The only competitive products are Sens4baby (USA) and Pregnabit
(Poland), these will not enter mass production before 2017
BioAnalyst – a comparable product does not exist.
CardioAnalyst – even PPG market leaders like OMRON, NONIN, POLAR do not
have this complex solution.
GeneAnalyst – Gene Expression Patterns analysis offer several top market leaders,
like NAIST and Mayo Clinic, but with very high prices! GeneAnalyst uses more
sophisticated statistical methods and therefore is much more prospective!
MacTrack – RTLS 3D localization system - UBISENSE, Inc. and ZEBRA, Inc (USA)
offer similar products but with much higher prices.
DV Buddy – Divers rescue system - a comparable product does not exist.

4. HealthAnalyst is an expert medical system, that directly assists physicians
and other health professionals with decision making tasks.
HealthAnalyst consists of 3 independent software packages:
BioAnalyst module for evaluation of biomedical parameters
CardioAnalyst module for evaluation of plethysmography
GeneAnalyst module for advanced gene expression patterns
Thanks the use of these packages is possible to realize very
successful diagnostics of prostate and breast cancer, diabetes and
cardiovascular system. Dutch patent applications are prepared.
This presentation is focused on GeneAnalyst concept
HealthAnalyst

5. Developed methods
PrenCare + = PrenCare + CardioScreen
CANSCREEN = BioAnalyst + GeneAnalyst
CARDIOSCREEN = CardioAnalyst +
BioAnalyst
DIABSCREEN = BioAnalyst + GeneAnalyst
Patient Monitor = MacTrack + CardioAnalyst

6. GeneAnalyst - A new approach of GEP
Identified significant genes may be used as predictors for regression
or classification models like -
PCA-based data, 32 factors used.
10 misclass. Mayo Clinic
Shrink-regression-based data,
24 genes used. 0 misclass- TSS
Support Vector Machine Classification based on classical and DVS-Reg predictors.
Supervised differential variables selection gives much better discrimination.

7. US partners
Trevor Hastie
Stanford University
Rob Tibshirani
Stanford University
Vladimir Vapnik
Princeton, NEC

8. 1.3rd Medical Faculty of Charles University (UK). Prague,
Czech Republic
2.Hospital Šumperk, Czech Republic
3.TRIVISION, Ltd., Czech Republic
4.Trilobyte Statistical Software, Ltd., Czech Republic
5:KB Soft, Ltd., Slovak Republic
NovioSys, B.V. | Transistorweg 5 | 6534 AT Nijmegen | The Netherlands |
http://noviosys.com
Partners

9. Thank you!