This document provides information for teachers on three laboratory activities about the respiratory system. Activity 14a has students investigate the organs, histology, diseases, and characteristics of the respiratory system using stations. It includes performing spirometry and lung auscultation. Activity 14b simulates respiratory distress using different sized straws. Students assess respiratory rate and pulse with and without exercise. Activity 14c has students measure air quality using petri dishes and determine safety using an index. Supplies needed and additional teaching notes are provided.