The document describes an innovative patient tracking and asset management system implemented at Hospital Universitari i Politecnic La Fe in Valencia, Spain. The system uses ZigBee wireless technology integrated with the hospital information system to precisely locate and identify patients and assets in real-time. It has led to improved patient safety, clinical workflow efficiency and optimized use of resources. While adjustment challenges remained, over 1,500 patients and 1,000 assets can now be tracked daily across the hospital with the system considered a reference for innovation.