INTRODUCTION
• The larynxis a component of the airway
connecting the phaynx to the Trachea.
• Its is a very essential structure because:
• It is a conduit of air during breating
• It has sphincteric action to protect the airway from
foreign bodies
• Its is the source of sound during phonation.
5.
• The larynxis a 5-7 cm long
structure.
• Its upper boundary starts at
the tip of the epiglottis,
opposite the 3rd to 4th,
cervical vertebra.
• Its lower end is at the lower
border of the cricoid
cartilage.
• This lies opposite the 6th
cervical vertebra.
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6.
EMBRYOLOGY
• The internallining of the larynx originates from
the endoderm
• The cartilages, muscles and ligaments originate
from the messenchyme of the 4th
and 6th
Pharyngeal arches.
• Initially the Laryngeal orifice is a sagittal slit,
however it later takes on a T shape as a result of
the rapid proliferation of the mesenchyme
around it.
7.
• Once themesenchyme transforms into the thyroid,
cricoid and arytenoid cartilages, the characteristic adult
shape of the laryngeal orifice is thus recognised.
• Concurrently as the cartilages differentiate, the
mucosal epithelium rapidly proliferates occluding the
laryngeal orifice.
• However this later recanalises with resultant creation of
the ventricles, being bound by folds which later
differential into the vestibular and vocal folds.
8.
• Since musculatureof the larynx is derived from
mesenchyme of the fourth and sixth pharyngeal
arches, all laryngeal muscles are innervated by
branches of the tenth cranial nerve, the vagus nerve.
• The superior laryngeal nerve innervates derivatives of
the fourth pharyngeal arch, and the recurrent
laryngeal nerve innervates derivatives of the sixth
pharyngeal arch.
• The trachea develops from the lung bud that
separates from the foregut.
The cricoid cartilage,a key landmark in the neck, indicates the:
• Level of the C6 vertebra.
• Site where the carotid artery can be compressed
against the transverse process of the C6 vertebra.
• Junction of the larynx and trachea.
• Joining of the pharynx and esophagus.
• Point where the recurrent laryngeal nerve enters
the larynx.
• Site that is approximately 3 cm superior to the
isthmus of the thyroid gland.
Cricoid cartilage
• Importantfrom structural & functional point
of view
– Base for entire larynx
– Support to arytenoid
– Attachment to intrinsic muscles
– Only part of cartilagenous framework that forms
continuous 360 degree ring
– Once injured or strictured , difficult to resect while
preserving laryngeal function
18.
Epiglottis
• Thin leafshaped fibro-cartilage,
situated in midline
• Upper free end broad & rounded,
projects up behind base of tongue
• Narrow base called pitiole
• This attachment forms lower limit of
pre-epiglottis space
19.
Arytenoids
• Paired cartilages,pyramidal in
shape
• Base articulated with cricoid
• PCA & LCA muscles attach on
muscular process
• Anterior angle elongated into
vocal process which receives
insertion of vocal ligament
21.
joints
• Cricothyroid joint:
–Its synovial
– Axis is transverse line between the two joints
– Recurrent laryngeal nerve lies immediately behind
this joint
• Cricoarytenoid joint:
– Synovial
– Allows rotatory and lateral gliding movts.
22.
LIGAMENTS
• EXTRINSIC:
– Thyrohyoidligament.
• Has a bursa which maybe associated with remnants of the
thryoglossal cysts.
• Forms the lateral wall of the pirifom recess
• Perforated by the superior laryngeal artery and internal
laryngeal nerve.
• Not part of the larynx but anchors it to the hyoid.
– HYOEPIGLOTTIC LIGAMENT
– THYROEPIGLOTTIC LIGAMENT
– CRICOTRACHEAL LIGAMENT
23.
INTRINSIC LIGAMENTS OFLARYNX
• QUANDRANGULAR MEMBRANE:
– Fibroelastic
– Extends between the arytenoids and the epiglottic
cartilages.
– Its upper border forms the aryepiglottic ligament
– Its lower border forms the Vestibular ligament
• CRICOTHYROID LIGAMENT:
– Anterior(median) cricothyroid ligament
– Paired Lateral cricothyroid ligaments(cricovoval)
24.
LATERAL CRICOTHYROID LIGAMENTS
•Attached below the upper margin of the
cricoid cartilage
• They pass up deep to the lamina of the thyroid
cartilage on each side. Anterioly attached to
the back of the thryoid angle midway between
the notch and lower border.
• Posterioly attached to the vocal processes.
• Its free edge forms the VOCAL LIGAMENTS
25.
Mucosa covering thevestibular and vocal
ligaments forms the vestibular and vocal folds
respectively.
• Rima glottis:
•ant 60% is intermembranous
• Posterior 40% is intercartilaginous
– 8mm wide post, in quiet respiration,
– Saggital length: 23mm male, 17mm in female.
30.
HISTOLOGY
• Mucosa
• isrespiratory hence:
• Pseudostratified columnar ciliated epithelium.
• Mucosa of anterior side of epiglottis is Stratified
squamous epithelium.
• Over Vocal folds: epithelium is stratified
squamous.
• Taste buds are present in the posterior epiglottic
surface and the aryepiglottic folds.
31.
HISTOLOGY Cont…
• LaminaPropria:
– Loose in all parts except over the vocal folds
where the mucous membrane is very firmly
attached.
• Hence in cases of Laryngeal oedema, the
swelling occurs above the rima glottis,
however still this is life threatening.
Intrinsic muscles
• alterthe length and tension of the vocal folds
and the size and shape of the rima glottidis
• ADDUCTORS OF THE VOCAL CORDS
– Lateral cricoarytenoids
– Transverse and oblique arytenoids
• ABDUCTORS OF THE VOCAL CORDS
– Posterior cricoarytenoid
34.
• SPHINCTERS:
– Lateralcricoarytenoids
– Transverse and oblique arytenoids
– Aryepiglottic muscles
• TENSORS:
– Cricothyroid muscles
• Bt tensing and elongating the cords, they vary and raise the pitch of
the voice.
• RELAXERS:
– Thyroartenoid muscles.
– Vocalis(medial part of thyroarytenoid muscle*)
Lymphatics
• The laryngeallymphatic vessels superior to the
vocal folds accompany the superior laryngeal
artery through the thyrohyoid membrane and
drain into the superior deep cervical lymph
nodes.
• The lymphatic vessels inferior to the vocal
folds drain into the pretracheal or paratracheal
lymph nodes, which drain into the inferior
deep cervical lymph nodes.
INNERVATION
• Superior Laryngealnerve:
– Internal laryngeal nerve: sensory to the supraglottic area.
– External laryngeal nerve: motor to cricothyroid.
• Recurrent Laryngeal nerve:
– Divides into the anterior and posterior branches.
– Ant branch: lat cricoarytenoid,thyroarytenoid, vocalis,
aryepiglottic and thyroepiglottic muscles
– Post branch: Post cricoarytenoid, transverse and oblique
arytenoids
– Sensory innervation to the mucosa of the infraglottic cavity.
TRACHEA
• The trachea,extending from the larynx into
the thorax, terminates inferiorly as it divides
into right and left main bronchi.
• It is a fibrocartilaginous tube, supported by
incomplete cartilaginous tracheal rings, that
occupies a median position in the neck
45.
• The trachealrings keep the trachea patent;
they are deficient posteriorly where the
trachea is adjacent to the esophagus.
• The posterior gap in the tracheal rings is
spanned by the involuntary trachealis muscle,
smooth muscle connecting the ends of the
rings
46.
• In adults,the trachea is approximately 2.5 cm
in diameter, whereas in infants it has the
diameter of a pencil.
• The trachea extends from the inferior end of
the larynx at the level of the C6 vertebra.
• It ends at the level of the sternal angle or the
T4–T5 IV disc, where it divides into the right
and left main bronchi
47.
CLINIC
• INJURY TOTHE LARYNGEAL NERVES
• CANCER OF THE LARYNX
• OEDEMA OF THE LARYNX
• CRICOTHYROIDOTOMY
• TRACHEOSTOMY
• SUPERIOR LARYNGEAL NERVEBLOCK
• CRASH INDUCTION/CRICOID PRESSURE
• FB LARYNX and TRACHEA
50.
RECURRENT LARYNGEAL NERVEINJURY
• The voice is poor initially because the paralyzed
vocal fold cannot adduct to meet the normal
vocal fold.
• Within weeks, the contralateral fold crosses the
midline when its muscles act to compensate
• results in the vocal fold on the affected side
assuming the position midway between
abduction and adduction.
51.
• When bilateralparalysis of the vocal folds
occurs, the voice is almost absent because the
vocal folds are motionless in a position that is
slightly narrower than the usually neutral
respiratory position. They cannot be adducted
for phonation, nor can they be abducted for
increased respiration, resulting in stridor
52.
• In progressivelesions of the recurrent
laryngeal nerve, abduction of the vocal
ligaments is lost before adduction; conversely,
during recovery, adduction returns before
abduction
53.
• Unilateral partialsection of the recurrent
laryngeal nerve results in a greater degree of
paralysis of the abductor muscles than of the
adductor muscles. The affected vocal fold
assumes the adducted midline position
54.
SUPERIOR LARYNGEAL NERVE
•Paralysis of the superior laryngeal nerve
causes anesthesia of the superior laryngeal
mucosa. As a result, the protective mechanism
designed to keep foreign bodies out of the
larynx is inactive, and foreign bodies can easily
enter the larynx.
55.
• Injury tothe external branch of the superior
laryngeal nerve results in a voice that is
monotonous in character because the
paralyzed cricothyroid muscle supplied by it is
unable to vary the length and tension of the
vocal fold.
56.
• To avoidinjury to the external branch of the
superior laryngeal nerve (e.g., during
thyroidectomy), the superior thyroid artery is
ligated and sectioned more superior to the
gland, where it is not as closely related to the
nerve.
• Test for quality of phonation before thyroid
surgery. Why?
57.
Cancer of theLarynx
• The incidence of cancer of the larynx is high in
individuals who smoke cigarettes or chew
tobacco.
• Most persons present with persistent
hoarseness, often associated with otalgia
(earache) and dysphagia. Enlarged pretracheal
or paratracheal lymph nodes may indicate the
presence of laryngeal cancer
58.
CRUSH INDUCTION
• Rapidsequence intubation(RSI) is a
medical procedure involving a prompt
induction of general anesthesia and
subsequent intubation of the trachea.
• RSI is typically used in an emergency setting or
for patients in the operating room.
59.
• The advantageof using rapid sequence
intubation is to quickly induce
unconsciousness and cause paralysis which
allow for easier tracheal intubation.
• ROLE OF CRICOID PRESSURE/ SELLICK
MANOUVRE IN RSI.
60.
CRICOTHYTODOTOMY
• A verticalor transverse incision is made in the skin in the
interval between the cartilages.
• The incision is made through the following structures:
the skin, the superficial fascia (beware of the anterior
jugular veins, which lie close together on either side of
the midline), the investing layer of deep cervical fascia,
the pretracheal fascia (separate the sternohyoid muscles
and incise the fascia), and the larynx.
• The larynx is incised through a horizontal incision
through the cricothyroid ligament and the tube inserted.
61.
• Complications
• Esophagealperforation esp in children in whom
the cross diameter of the larynx is so small.
• Hemorrhage: The small branches of the
superior thyroid artery that occasionally cross
the front of the cricothyroid membrane to
anastomose with one another should be
avoided.
62.
TRACHEOSTOMY
• An openingis made in the trachea between
the first and second tracheal rings or through
the second through fourth rings.
63.
WHAT TO WATCHOUT FOR
• The inferior thyroid veins arise from a venous
plexus on the thyroid gland and descend
anterior to the trachea.
• A small thyroid ima artery is present in
approximately 10% of people; it ascends from
the brachiocephalic trunk or the arch of the
aorta to the isthmus of the thyroid gland.
64.
• The leftbrachiocephalic vein, jugular venous
arch, and pleurae may be encountered,
particularly in infants and children.
• The thymus covers the inferior part of the
trachea in infants and children.
• The trachea is small, mobile, and soft in
infants, making it easy to cut through its
posterior wall and damage the esophagus.
65.
• Most complicationsresult from not
adequately palpating and recognizing the
thyroid, cricoid, and tracheal cartilages and
not confining the incision strictly to the
midline.
66.
• Hemorrhage: Theanterior jugular veins.
• the isthmus of the thyroid gland is transected, secure
the anastomosing branches of the superior and inferior
thyroid arteries that cross the midline on the isthmus.
• Nerve paralysis:
• Pneumothorax:
• Esophageal injury