This document summarizes the first lecture of a Natural Language Processing course. It introduces NLP and its goal of understanding human language. It discusses the different levels of language processing from sounds to context. Examples are given for each level including part-of-speech tagging, parsing sentences, and resolving pronoun references. Statistical and data-driven approaches to NLP are also outlined, including dealing with ambiguity. Finally, topics to be covered in the course are listed, such as parsing, word sense disambiguation, and applications like question answering.