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Dr. Yasser Al-Fakey
M.D., M.Sc (Ophth.), FRCS
EMBRYOLOGY OF THE
EYE
 This highly specialized sensory organ is derived
from neural ectoderm, mesoderm and surface
ectoderm.
 The eye is essentially an outgrowth from the
brain (neural ectoderm).
 Started as Optic vesicle connected to the
forebrain by Optic stalk.
EMBRYOLOGY (cont.)
 Invagination of both the optic vesicle to form
Optic cup and the optic stalk to form Choroidal
fissure inferiorly.
 Surface ectoderm invaginate to form the lens
vesicle.
 Mesodermal tissues invade the developing eye to
share in vascular, muscular and supportive
tissues of the eye.
DEVELOPMENT OF THE
EYE AFTER BIRTH
 At birth, the eye is relatively large in relation to
the rest of the body.
 The eye reaches full size by the age of 8 years.
 The lens continues to enlarge throughout the
life.
 The iris has a bluish color due to little or no
pigment on the anterior surface.
 During early infant life, the cornea & sclera can
be stretched by raised IOP → enlargement of
the eye.
THE ORBIT
 As a socket, contains & protect the eye.
 The weakest parts are the floor & the medial
wall.
 Seven bones contribute the bony orbit.
 Surrounded by nasal sinuses.
 Important openings are:
 Optic foramen.
 Superior orbital fissure.
 Inferior orbital fissure.
THE EXTRAOCULAR
MUSCLES
 Four recti & two
oblique muscles.
 All are supplied by
Oculomotor n.
except superior
oblique (Trochlear
n.) & lateral rectus
(Abducent n.).
The Visual Pathway
 Visual Pathway: Three
neurons
1. Bipolar cell, lies
within the retina.
2. Ganglion cell,
synapse in lateral
geniculate body.
3. Third neuron
terminates in visual
cortex.
THE EYELIDS
 They provide a protective covering for the
eye.
 The lids are closed by Orbicularis oculi
muscle (Facial n.) and opened with
Levator palpebrae muscle
(Oculomotor n.), Muller’s muscle
(Sympathetic supply) & Lower lid
retractors.
CONJUNCTIVA
 Three parts:
1. Bulbar conjunctiva.
2. Palpebral conjunctiva.
3. Forniceal conjunctiva.
 The stroma (no adenoid
tissues until 3 months after
birth).
 Follicles & Papillae.
 Injection and chemosis.
 Limbus.
THE LACRIMAL
APPARATUS
 Lacrimal gland secrets tears into the upper fornix
of the conjunctival sac which are spread over the
surface of the cornea as a tear film by blinking of
the lids.
 Tears accumulate at the inner canthus and drain
into the lacrimal sac via the puncta & canaliculi.
 The sac is continuous inferiorly with the
nasolacrimal duct which opens into the nasal
cavity just beneath the inferior turbinate.
THE EYE (GLOBE)
 Two spheres with different radii:
- Cornea, window of the eye.
- Sclera, opaque shell.
*** The eye measures approximately
24 mm in all its main diameters.
The coats of the eye
*** Three layers:
 The outer: inelastic coat, transparent cornea
and opaque sclera.
 The middle, vascular coat, The Uvea:
choroid, ciliary body and iris.
 The inner: The Retina, extends forwards to
within 6 mm of the limbus.
The Chambers of The Eye
***Three optically clear spaces:
 The anterior chamber, in front of the iris
 The posterior chamber, immediately behind the
iris. These two chambers which communicate
through the pupil are filled with clear aqueous
humour.
 The vitreous cavity: filled by gel-like structure,
The Vitreous.
The Lens
 The crystalline lens is the only structure
continuously growing throughout the life.
 Changeable refractive media.
 Capsule, epithelium and lens fibers.
 Congenital anomalies and effect of systemic
diseases.
 Cataract.
Retina and Vitreous
 Vitreous attachment.
 Optic nerve head, macula, fovea, retinal
background, Ora serrata, and retinal vasculature.
 Effect of systemic diseases.
 Retinal detachment.
Optics of the Eye
 The eye is like a camera. Light must have a
clearly pathway to be clearly focused on the
sensory receptors of the retina, i.e., Clear
cornea, anterior chamber, lens and vitreous
cavity.
 The Refractive power of the eye is about ± 58
dioptres.
Optics of the Eye (cont.)
 The cornea is the major refracting element of the
eye with a power of approximately 40 dioptres. If
the curvature is greater in one meridian than the
other→ Astigmatism
 The refractive power of the lens is about 17
dioptres at rest. Accommodation able to change
the power of the lens markedly depends on age.
 Emmetropia: Optically normal eye in which rays
of light from a distant object are focused on the
retina without accommodation.
 Myopia: Light focused on front of the retina,
corrected by concave lens.
 Hypermetropia (hyperopia): Light focused
behind the retina, corrected by convex lens.
The intraocular pressure
 The pressure within the eye is maintained at a
steady level by continuous formation & drainage
of aqueous.
 Aqueous is secreted by the ciliary epithelium →
posterior chamber → anterior chamber (through
the pupil ) → drained through the anterior
chamber angle.
 The intraocular pressure, (IOP), is normally 10
– 21 mmHg; increased IOP called Glaucoma.
 High IOP almost always due to an obstruction of
aqueous outflow.
VISION
 The retina:
- The central retina contains yellow pigment,
Xanthophyll, the so called macula lutea ( yellow
spot).
- It is divided into retinal pigment epithelium
& neurosensory retina.
- Photoreceptors contains visual pigment
which consists of a large protein (opsin)
attached to retinal (vitamin A
aldehyde).
VISION (cont.)
 Light splits the opsin from the retinal with
initiation of a graded electrical potential →
Transmitted through the visual pathway to be
processed in the visual cortex (occipital lobe)
→ vision sense.
 Visual Pathway: Three neurons
1. Bipolar cell, lies within the retina.
2. Ganglion cell, synapse in lateral geniculate
body.
3. Third neuron terminates in visual cortex.
Lacrimal Apparatus
 Tear secretion.
 Layers of precorneal tear film.
 Drainage of tear.

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01- Anatomy and Physiology of the ey ppt

  • 1.
  • 2. Dr. Yasser Al-Fakey M.D., M.Sc (Ophth.), FRCS
  • 3.
  • 4. EMBRYOLOGY OF THE EYE  This highly specialized sensory organ is derived from neural ectoderm, mesoderm and surface ectoderm.  The eye is essentially an outgrowth from the brain (neural ectoderm).  Started as Optic vesicle connected to the forebrain by Optic stalk.
  • 5. EMBRYOLOGY (cont.)  Invagination of both the optic vesicle to form Optic cup and the optic stalk to form Choroidal fissure inferiorly.  Surface ectoderm invaginate to form the lens vesicle.  Mesodermal tissues invade the developing eye to share in vascular, muscular and supportive tissues of the eye.
  • 6.
  • 7. DEVELOPMENT OF THE EYE AFTER BIRTH  At birth, the eye is relatively large in relation to the rest of the body.  The eye reaches full size by the age of 8 years.  The lens continues to enlarge throughout the life.  The iris has a bluish color due to little or no pigment on the anterior surface.  During early infant life, the cornea & sclera can be stretched by raised IOP → enlargement of the eye.
  • 8.
  • 9. THE ORBIT  As a socket, contains & protect the eye.  The weakest parts are the floor & the medial wall.  Seven bones contribute the bony orbit.  Surrounded by nasal sinuses.  Important openings are:  Optic foramen.  Superior orbital fissure.  Inferior orbital fissure.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17. THE EXTRAOCULAR MUSCLES  Four recti & two oblique muscles.  All are supplied by Oculomotor n. except superior oblique (Trochlear n.) & lateral rectus (Abducent n.).
  • 18.
  • 19.
  • 20.
  • 21. The Visual Pathway  Visual Pathway: Three neurons 1. Bipolar cell, lies within the retina. 2. Ganglion cell, synapse in lateral geniculate body. 3. Third neuron terminates in visual cortex.
  • 22. THE EYELIDS  They provide a protective covering for the eye.  The lids are closed by Orbicularis oculi muscle (Facial n.) and opened with Levator palpebrae muscle (Oculomotor n.), Muller’s muscle (Sympathetic supply) & Lower lid retractors.
  • 23.
  • 24.
  • 25. CONJUNCTIVA  Three parts: 1. Bulbar conjunctiva. 2. Palpebral conjunctiva. 3. Forniceal conjunctiva.  The stroma (no adenoid tissues until 3 months after birth).  Follicles & Papillae.  Injection and chemosis.  Limbus.
  • 26. THE LACRIMAL APPARATUS  Lacrimal gland secrets tears into the upper fornix of the conjunctival sac which are spread over the surface of the cornea as a tear film by blinking of the lids.  Tears accumulate at the inner canthus and drain into the lacrimal sac via the puncta & canaliculi.  The sac is continuous inferiorly with the nasolacrimal duct which opens into the nasal cavity just beneath the inferior turbinate.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31. THE EYE (GLOBE)  Two spheres with different radii: - Cornea, window of the eye. - Sclera, opaque shell. *** The eye measures approximately 24 mm in all its main diameters.
  • 32.
  • 33. The coats of the eye *** Three layers:  The outer: inelastic coat, transparent cornea and opaque sclera.  The middle, vascular coat, The Uvea: choroid, ciliary body and iris.  The inner: The Retina, extends forwards to within 6 mm of the limbus.
  • 34.
  • 35.
  • 36. The Chambers of The Eye ***Three optically clear spaces:  The anterior chamber, in front of the iris  The posterior chamber, immediately behind the iris. These two chambers which communicate through the pupil are filled with clear aqueous humour.  The vitreous cavity: filled by gel-like structure, The Vitreous.
  • 37.
  • 38.
  • 39. The Lens  The crystalline lens is the only structure continuously growing throughout the life.  Changeable refractive media.  Capsule, epithelium and lens fibers.  Congenital anomalies and effect of systemic diseases.  Cataract.
  • 40.
  • 41.
  • 42.
  • 43. Retina and Vitreous  Vitreous attachment.  Optic nerve head, macula, fovea, retinal background, Ora serrata, and retinal vasculature.  Effect of systemic diseases.  Retinal detachment.
  • 44.
  • 45.
  • 46.
  • 47.
  • 48.
  • 49.
  • 50.
  • 51. Optics of the Eye  The eye is like a camera. Light must have a clearly pathway to be clearly focused on the sensory receptors of the retina, i.e., Clear cornea, anterior chamber, lens and vitreous cavity.  The Refractive power of the eye is about ± 58 dioptres.
  • 52.
  • 53. Optics of the Eye (cont.)  The cornea is the major refracting element of the eye with a power of approximately 40 dioptres. If the curvature is greater in one meridian than the other→ Astigmatism  The refractive power of the lens is about 17 dioptres at rest. Accommodation able to change the power of the lens markedly depends on age.
  • 54.
  • 55.  Emmetropia: Optically normal eye in which rays of light from a distant object are focused on the retina without accommodation.  Myopia: Light focused on front of the retina, corrected by concave lens.  Hypermetropia (hyperopia): Light focused behind the retina, corrected by convex lens.
  • 56.
  • 57. The intraocular pressure  The pressure within the eye is maintained at a steady level by continuous formation & drainage of aqueous.  Aqueous is secreted by the ciliary epithelium → posterior chamber → anterior chamber (through the pupil ) → drained through the anterior chamber angle.  The intraocular pressure, (IOP), is normally 10 – 21 mmHg; increased IOP called Glaucoma.  High IOP almost always due to an obstruction of aqueous outflow.
  • 58. VISION  The retina: - The central retina contains yellow pigment, Xanthophyll, the so called macula lutea ( yellow spot). - It is divided into retinal pigment epithelium & neurosensory retina. - Photoreceptors contains visual pigment which consists of a large protein (opsin) attached to retinal (vitamin A aldehyde).
  • 59. VISION (cont.)  Light splits the opsin from the retinal with initiation of a graded electrical potential → Transmitted through the visual pathway to be processed in the visual cortex (occipital lobe) → vision sense.  Visual Pathway: Three neurons 1. Bipolar cell, lies within the retina. 2. Ganglion cell, synapse in lateral geniculate body. 3. Third neuron terminates in visual cortex.
  • 60.
  • 61. Lacrimal Apparatus  Tear secretion.  Layers of precorneal tear film.  Drainage of tear.