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CASE REPORT ON POST STREPTOCOCCAL
GLOMERULONEPHRITIS
An 7-year old boy was admitted inour hospital with a two-day history of fewer,tonsillopharyngitis,
and stomach ache associatedwith vomiting,periorbital edemaand body edema.A boy was
hospitalizedfor9 days. Biochemical and clinical parameters were observed.The boy was 40kg
weight,140cm high,dispnoic,euhydric,with expressededemaandblood pressure 175/120 mmHg.
After the hematologicanalysesthe next valuesof measuredparameterswere recorded:
erythrocytes3.1x1012/L, hemoglobin94g/L, hematocrit0.31 L/L, leukocytes12.4x109/L, (neutrophils
0.58 x109/L, lymphocytes0.36x109/L, monocites0.06 x109/L). The valuesof ureawere 3.2, 2.9, and 3.1
mmol/Linthe first, fifthandtenthday,respectively.The valuesof creatininewere 41,69, and 48 mol/L
inthe first,fifth,tenthday,respectively;clearance was85 mmol/L;albuminwas29 and 30 g/dL inthe
firstand tenthday,respectively;Na+150 mmol/L,K+4.8 mmol/L,alkaline phosphatase519-476 U/L,
antistreptolysine Otest600 U/mL, C reactive protein
After the urine analysis, the valuesof erythrocyteswere 15-20per HPF,and the valuesof leukocyets
were 2-3 HPF.
ECHO of abdomen: leftkidneywithoutchanges,rightkidneyindiameter78x40mm.Diuresiswas700ml
per24h
DIAGNOSIS:The valuesof biochemical andclinical parametersrecordedatthe admissionindicatedthat
the patientdevelopedPSGN.
TREATMENT; Afterhospital admission,patientwastreatedwith –
penicillinduringthe periodof 10 days,
antihypertensive medications(captopril,furosemide),
includingrestricteddietof salt.
Afterthe treatment,patientbecame better.Ondemissionitwasfoundproteinuriaand
microhematuria.
DISCUSION
Post-streptococcal acute glomerulonephritisisone of the mostimportantandintriguingconditionsin
the pediatricnephrology.Althoughthe eventualoutcome isexcellentinmostcases, PSAGN remainsan
importantcause of acute renal failure andhospitalizationforchildreninbothdevelopedand
underdevelopedareas[5].Post-streptococcal acute glomerulonephritisremainsanimportantnon
suppurative complicationof groupA streptococcal infectionworldwide.The estimatedworldwide yearly
burdenof PSAGN is472,000 cases;approximately404,000 of those occur inchildren
CONCLUSION
PSGN is veryseriousdisease,whichleavessevere complicationsif the validtherapywithpenicillinisnot
usedinproprietytime,duringthe recommendedperiodof 10day

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child disease

  • 1. CASE REPORT ON POST STREPTOCOCCAL GLOMERULONEPHRITIS An 7-year old boy was admitted inour hospital with a two-day history of fewer,tonsillopharyngitis, and stomach ache associatedwith vomiting,periorbital edemaand body edema.A boy was hospitalizedfor9 days. Biochemical and clinical parameters were observed.The boy was 40kg weight,140cm high,dispnoic,euhydric,with expressededemaandblood pressure 175/120 mmHg. After the hematologicanalysesthe next valuesof measuredparameterswere recorded: erythrocytes3.1x1012/L, hemoglobin94g/L, hematocrit0.31 L/L, leukocytes12.4x109/L, (neutrophils 0.58 x109/L, lymphocytes0.36x109/L, monocites0.06 x109/L). The valuesof ureawere 3.2, 2.9, and 3.1 mmol/Linthe first, fifthandtenthday,respectively.The valuesof creatininewere 41,69, and 48 mol/L inthe first,fifth,tenthday,respectively;clearance was85 mmol/L;albuminwas29 and 30 g/dL inthe firstand tenthday,respectively;Na+150 mmol/L,K+4.8 mmol/L,alkaline phosphatase519-476 U/L, antistreptolysine Otest600 U/mL, C reactive protein After the urine analysis, the valuesof erythrocyteswere 15-20per HPF,and the valuesof leukocyets were 2-3 HPF. ECHO of abdomen: leftkidneywithoutchanges,rightkidneyindiameter78x40mm.Diuresiswas700ml per24h DIAGNOSIS:The valuesof biochemical andclinical parametersrecordedatthe admissionindicatedthat the patientdevelopedPSGN. TREATMENT; Afterhospital admission,patientwastreatedwith – penicillinduringthe periodof 10 days, antihypertensive medications(captopril,furosemide), includingrestricteddietof salt. Afterthe treatment,patientbecame better.Ondemissionitwasfoundproteinuriaand microhematuria. DISCUSION Post-streptococcal acute glomerulonephritisisone of the mostimportantandintriguingconditionsin the pediatricnephrology.Althoughthe eventualoutcome isexcellentinmostcases, PSAGN remainsan
  • 2. importantcause of acute renal failure andhospitalizationforchildreninbothdevelopedand underdevelopedareas[5].Post-streptococcal acute glomerulonephritisremainsanimportantnon suppurative complicationof groupA streptococcal infectionworldwide.The estimatedworldwide yearly burdenof PSAGN is472,000 cases;approximately404,000 of those occur inchildren CONCLUSION PSGN is veryseriousdisease,whichleavessevere complicationsif the validtherapywithpenicillinisnot usedinproprietytime,duringthe recommendedperiodof 10day