Biological Activity of Cladribine: Cladribine (Leustatin) is a drug used to treat hairy cell leukemia (leukemic reticuloendotheliosis) and multiple sclerosis. [1]As a purine analog, it is a synthetic anti-cancer agent that also suppresses the immune system. Chemically, it mimics the nucleoside adenosine and thus inhibits the enzyme adenosine deaminase, which interferes with the cell's ability to process DNA. [1]It is easily destroyed by normal cells except for blood cells, with the result that it produces relatively few side effects and results in very little non-target cell loss. [1] -------------------------------------------------------------------------------- References on Cladribine: [1] http://en.wikipedia.org/wiki/Cladribine [2] http://www.rxlist.com/leustatin-drug.htm

1. Product Information Novel Kinase Inhibitors
for cell signaling & oncology research
Toll Free:
S1199 Cladribine (877)796-6397
-- USA and Canada only --
» Antimetabolites
Fax:
+1-713-796-9816
Technical Data:
Orders
M.Wt: 285.69
Cl +1-713-922-4115
Formula: C10H12ClN5O3 enquiry@selleckchem.com
Solubility: DMSO N N OH
O
Purity: 99% H 2N Tech Support
N
OH tech@selleckchem.com
Storage: at -20℃ 2 years N
(chemistry support)
CAS No.: 4291-63-8 Synonyms: Leustatin techbio@selleckchem.com
(bio support)
Web
Biological Activity
www.selleckchem.com
Cladribine (Leustatin) is a drug used to treat hairy cell leukemia (leukemic reticuloendotheliosis)
and multiple sclerosis. [1]As a purine analog, it is a synthetic anti-cancer agent that also suppresses
the immune system. Chemically, it mimics the nucleoside adenosine and thus inhibits the enzyme
adenosine deaminase, which interferes with the cell's ability to process DNA. [1]It is easily destroyed
by normal cells except for blood cells, with the result that it produces relatively few side effects
and results in very little non-target cell loss. [1]
Selleck Overnight Delivery Service
References
[1] http://en.wikipedia.org/wiki/Cladribine
Return Policy
[2] http://www.rxlist.com/leustatin-drug.htm
Please inspect packages immediately upon
receipt and notify customer service within
3 days of delivery of any damage or
discrepancies.Our team will take quick and
appropriate action to correct any problem.
MSDS & CoA Goods ordered in error can only be accepted
Please visit www.selleckchem.com to download MSDS and CoA. for return if made within 3 days of delivery,
are unopened,have been stored correctly and
are in good condition. Should you wish to
return any item(s), prior authorization must
Notes be received from our customer service team.
Returns accepted will be subject to a 30%
restocking charge.
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. For all product returns and product replace-
ments,please contact Selleck directly by
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleckchem products, stored under info@selleckchem.com or
the recommended conditions, are stable for two year. Products are sometimes shipped at a temperature that differs from the recommended +1-713-922-4115.
storage temperature,most are recommended stored at -20℃.Many products are stable in the short-term at temperatures that differ from that Please have on hand, the invoice number,
required for long-term storage. We ensure that the product is shipped under conditions that will maintain the quality of the product, but save purchase order number,air bill number and
you shipping charges by using the most economical storage conditons for an overnight shipment. Upon receipt of the product, follow the storage approximate date of shipment/receipt.
recommendations on the product data sheet.
© Copyright 2010 Selleck chemicals