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Best practices in the perioperative care of
obstructive sleep apnea
Ass Prof Karl Franklin MD,
Dept Surgery, Umeå, Sweden
52 years, obese, snoring, taxi driver,
smokes, diabetes, daytime sleepiness
Sleep apnea covariates with early death, stroke, and
traffic accidents.
CPAP and mandibular repositioning appliances are
effective. No evidence for surgery, except for side-
effects.
Nordic HTA report, SBU 2007
Sleep 2009; 32: 27-36.
Mandibular Repositioning Appliances
MRA
Liao. Anesthesiology 2013
0
5
10
15
20
25
30
35
Control n=66 Auto PAP n=40
Preop AHI
Postop AHI
Apnea-hypopneaindexApnea-hypopneaindex
N.s. p<0.001
Randomized controlled trial
Mutter TC, Anesthesiology 2014
20488 Surgeries attended by anesthesiolgist, Canada
Post-op complications
0
1
2
3
CV compl Pulm compl
No OSA
n=16,277
Undiag OSA
n=1,571
CPAP treat OSA
n=2,640
p=0.009
N.s.
Untreated OSA on Cardio Pulmonary complications after
abdominal or vascular surgeries, US
00
02
04
06
08
10
Cardiopulmonary
complica on
Reintuba on Myocardial
infarc on
Non-OSA (24196)
Untreated OSA (1465)
CPAP treated OSA (1181)
p=0.003
p=0.031
p=0.001
Percent
Abdelsattar ZM et al. Sleep 2015
O´Gorman Chest 2013
0
2
4
6
8
10
12
Lenght of stay,
days
Complication,
numbers
Pulm Infiltrate or
atelectais, n
Controls n=43
Auto-CPAP n=43
Number
N.s.
N.s.
Randomized controlled trial, Orthopedic surgery
OSA patients on positive airway pressure (PAP)
should use it pre- and postoperative.
Evidence: Moderate, Recommendation: Strong
SASM guidelines Anesth Analg 2016:123:452
Sleep apnea patients not adherent or decline PAP
Proceed with surgery after discussion of pro and cons.
Evidence: Low, Recommendation: Weak
Improve compliance! -Consult a sleep apnea specialist
SASM guidelines Anesth Analg 2016:123:452
High probability of obstructive sleep apnea
Patient, surgeon, anesthesiologist informed on increased
post-op risks
Evidence: Low, Recommendation: Strong
Individual decision for further evaluation and treatment
Evidence: Low, Recommendation: Weak
SASM guidelines Anesth Analg 2016:123:452
Honolulu airport 19
What´s the problem about CPAP?
What´s the problem about CPAP?
Noisy
Complicated
Not sexy
Thank you
karl.franklin@umu.se
0
10
20
30
40
50
60
Young
1993
Franklin
2013
Heinzer
2015
Young
1993
Heinzer
2015
Percent Moderate and severe OSA in the popula on
AHI >15
Women Men

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Perioperative treatment of sleep apnoea