4. Observed in 85% - It may be the initial
cutaneous manifestation of HIV disease
Involves hairy region of scalp, face, axillae
and pubic region.
Histologically- inflammatory changes &
keratinocyte necrosis at dermoepidermal
junction
Management-Topical steroids and oral
Imidazoles (antifungal agents).
5.
6. Pre-existing psoriasis may worsen and form
guttate lesions, plaques or pustules or
become erythrodermic.
Occur on extensor surfaces and scalp
Management-Standard topical therapy,
systemic retinoids.
7.
8. Xerosis or Acquired Ichthyosis is frequently
observed in more than 30% patients with HIV
infection.
It is often accompanied by severe generalized
itching.
Starts on the lower extremities
Histologically- hyperkeratosis with a thin
granular layer
9.
10. PPE is asso. with low CD4 count (<100 cells/pl)
It is characterized by marked pruritus and a
greater involvement of the extremities than the
trunk or face.
Clinically, the eruptions are follicular or non-
follicular lesions (papules, pustules and nodules)
often with secondary change(excoriation, prurigo
nodularis)
11.
12. Cutaneous hyperpigmentation is frequently
seen in late stage HIV
It is associated with oral pigmentation and
involvement of palms.
13. It is high in untreated HIV and increasing
immunodeficiency
The commom drug reaction patterns seen
are-
1) Toxic epidermis necrolysis(TEN), Steven
Johnson Syndrome(SJS)
2) Genital and Oral ulcers
3) Systemic reactions, including fever,
leukopenia, thrombocytopenia, hepatitis,
and nephritis
14.
15. It is the most common neoplastic complication
of HIV
begins as pink macules that enlarge and become
palpable.
They grow into purplish or brown plaques which
may become hemorrhagic and nodular.
Common sites are trunk, leg, arm, face and oral
cavity.
Excoriation-a linear break in the skin surface, usually covered with blood or serous crusts.
Prurigo nodularis-characterised by pruritic (itchy) nodules which usually appear on the arms or legs.