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1. ORAL LIPOMA
Professional Dental E-Class
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2. Learning Objectives
•Case Presentation
•Variants of Oral Lipomas
•Etio-Pathogenesis
•Investigations
•Differential Diagnoses
•Histopathology
•Treatment

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4. Case Presentation 1

5. Case 1
•42-year-old female
•Gastroesophageal Reflux
•Painless sublingual mass
•Gradual size increments
•Interference with speech and
mastication

6. Case 1 --
Clinical exam

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8. Case 1 -- Treatment
•Excised for histopathology

9. Case 1 --
Progress

10. Case Presentation 2

11. Case 2
•77-year-old male
•Swelling for one year
•Gradual size increments
•Nil for medical history

12. Case 2 --
Clinical

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15. Case Presentation 3

16. Case 3
•80-year-old man
•Large tongue and speech difficulty
•Significant medical history
•Heavy drinker

17. Case 3 -- Clinical

18. Case 3 -- Clinical

19. Case 3 -- Clinical

20. Case 3 -- Surgery

21. Case 3 -- Surgery

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23. Case 3 -- Post operative

24. Most common neoplasms
of mesenchymal origin

25. Almost always benign

27. Clinical Features
•Slow growing
•Painless
•Smooth surfaced
•Yellowish tinge
•Well-circumscribed

31. Clinical Features
•Mobile
•Fluctuant
•Negative aspiration | Slip sign
•Commoner in males
•After 4th decade
•Isolated or Syndromic

32. Syndromic Associations
•Neurofibromatosis
•Gardner's Syndrome
•Benign Symmetric Lipomatosis
•Proteus Syndrome
•Hemifacial Hypertrophy

33. Etio-Pathogenesis
•Genetics
•Local Trauma
•Obesity
•Alcohol Abuse
•Liver Disease
•Diabetes Mellitis
•Elevated blood lipids

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35. Theories of
Lipomagenesis

36. Etio-Pathogenesis- Theories
•Hypertrophic Theory
•Metaplastic Theory

37. Clinical variants of lipomas
•Infiltrative
•Non-Infiltrative
•Intraosseous

38. Histopathology

41. Spindle Cell Lipoma

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45. Pleomorphic Lipoma

46. Fibrolipoma

49. Other variants

50. Investigations

51. Investigations
•Histology
•Imaging
•Fine needle aspiration cytology

52. Differential Diagnoses

53. Differential Diagnosis
•Any soft tissue swelling

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55. Treatment
•Surgical Excision
•Intralesional Steroids
•Curretage

56. • Ben-Zion Joshua, Lipa Bodner, and Ruthy Shaco-Levy, “Intramuscular (Infiltrating) Lipoma of the Floor of the
Mouth,” Case Reports in Medicine, vol. 2018, Article ID 3529208, 3 pages, 2018. [CC BY-3.0]
• Masanori Kudoh, Ken Omura, Arata Satsukawa, et al., “Symmetric Lipomatosis Arising in the Tongue Presenting as
Macroglossia and Articulatory Disorder,” Case Reports in Otolaryngology, vol. 2016, Article ID 2061649, 5 pages,
2016. [CC BY-4.0]
• Masayasu Iwase, Naotaka Saida, and Yoko Tanaka, “Fibrolipoma of the Buccal Mucosa: A Case Report and Review of
the Literature,” Case Reports in Pathology, vol. 2016, Article ID 5060964, 4 pages, 2016 [CC BY-4.0]
• Giorgio Iaconetta, Marco Friscia, Atirge Cecere, Antonio Romano, Giovanni Dell’Aversana Orabona and Luigi
Califano. Rare fibrolipoma of the tongue: a case report. Journal of Medical Case Reports, 2015. 9:177 [CC BY-4.0]
• Ahmet Hançer, Can Özbay, Serap Karaarslan, and Muzaffer Balaban, “Spindle Cell Lipoma of the Soft Palate,” Case
Reports in Otolaryngology, vol. 2015, Article ID 813240, 3 pages, 2015.
• L. K. Surej Kumar, Nikhil Mathew Kurien, Varun B. Raghavan, P. Varun Menon, and Sherin A. Khalam, “Intraoral
Lipoma: A Case Report,” Case Reports in Medicine, vol. 2014, Article ID 480130, 4 pages, 2014. [CC BY-3.0]
• Mesolella, M. , Ricciardiello, F. , Oliva, F. , Abate, T. , Lullo, A. and Marino, A. (2014) Parotid Lipoma: A Case Report.
Case Reports in Clinical Medicine, 3, 437-442. [CC BY-4.0]
• E. Manor, N. Sion-Vardy, P. Brennan and L. Bodner, "Spindle Cell Lipoma of the Oral Cavity: A Clinico-Pathologic
Analysis of 35 Reported Cases," Surgical Science, Vol. 4 No. 3, 2013, pp. 196-201.[CC BY-4.0]

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