Pressure is a primary thermodynamic parameter of central importance in molecular conformation, chemical equilibrium, reaction kinetics, and molecular interactions. The Barocycler HUB440 is capable of creating and controlling hydrostatic pressure from 35 Bar (~500 psi) up to 4,000 Bar (~58,000 psi). The Barocycler HUB440 is the first portable, automated, bench-top, high pressure generator for the life sciences laboratory. Find out more at: www.pressurebiosciences.com

1. Pressure BioSciences, Inc.
Barocycler HUB440 TM
Pressure Generator
State-of-the-Art
High Pressure Generator
for Multiple Laboratory Applications
The Barocycler HUB440 is Capable of Creating and Controlling Hydrostatic Pressure
from 35 Bar up to 4,000 Bar (~500 psi to ~58,000 psi)
The Barocycler HUB440 is the Hub that Powers Your Laboratory’s High Pressure Needs
Discovery Starts with Sample PreparationTM

2. Pressure is a primary thermodynamic parameter of central
importance in molecular conformation, chemical equilibrium,
reaction kinetics, and molecular interactions.
The Barocycler HUB440 is capable of creating and controlling
hydrostatic pressure from 35 Bar (~500 psi) up to 4,000 Bar
(~58,000 psi). The Barocycler HUB440 is the first portable,
automated, bench-top, high pressure generator for the life
sciences laboratory.
Barocycler HUB440
High Pressure Generator
State-of-the-Art High Pressure Equipment
for a Wide Variety of Laboratory Applications
• EPR/NMR spectroscopy • UPLC
• Deep sea biology • Chemical synthesis
• Thermodynamic experiments • Protein aggregation
• Material Science • Vaccine development
• High pressure freezing • Protein conformation studies
• Solvent extraction • Compressibility measurements
• Chemical reaction kinetics • High pressure food science
• Pathogen inactivation • Spore germination studies
• Control of enzymatic activity • Cell lysis
Features
• Maximum Operating Pressure 4,000 Bar (~58,000 psi)
• Minimum Operating Pressure 35 Bar (~ 500 psi)
• Intensifier Displacement : 0.22 in³ (3.6 mL)
• Compact and Portable (17” X 12” X 9”, 55 lbs)
• Built for Expansion
• Manual or Analog Signal External Control
• Optional Data Acquisition and Control System with PBI software
• Rapid Pressure Change (full pressure in less than 2 seconds)
• Air Pressure and 24VDC power source required (suitable for mobile field use).
AC adapter is supplied.

3. Barocycler HUB440
High Pressure Generator
1. Open frame design for easy reconfiguration
2. Repositionable carry handles
3. Luer-Lock syringe injection port for system fluid
4. Rear connector for external control
5. Mating connector cable provided
6. 9/16”-18 standard ¼” tubing high pressure port
7. Intensifier air pressure gauge
8. System error indicator light
9. Control pressure LED display
10. Inlet pressure gauge
11. Valve position indicator
12. Input power indicator light
13. Recessed manual control panel

4. Barocycler HUB440
High Pressure Generator
The HUB440 is the first automated, bench-top, high pressure
generator for the life sciences laboratory. The HUB440 has
an optional USB-powered computer interface* capable of
complex data acquisition and control. A user can easily
develop custom LabVIEW™ programs to interface with
spectroscopy, HPLC, and other analytical instrumentation.
A broad selection of custom options is available from
Pressure BioSciences, your trusted partner in high pressure
bioscience.
*Note: Computer Not Supplied

5. Optional HUB Controls Software Specifications
Developed using National Instruments LabView
Modes of operation:
• Barocycler Emulator
• Barostat: Pressure hold with transducer feedback
• Wave Generator: Sine, Triangular, Square Wave, Saw Tooth,
• Arbitrary table lookup
• Manual control mode
Data capture from up to 2 pressure transducers
Temperature logging – up to 2 channels, thermocouples Type K, T, S
Data acquisition – up to 12 customizable channels available
Data Logging capability
Data import /export – interface with Microsoft Excel® file I/O
Unlimited potential for instrument control and data acquisition
HUB Controls v.1.01
User Interface:
PCT Emulator Custom Arbitrary
Time Table
Also included are Sine Wave, Square Wave, Triangular Wave, Saw Tooth
profiles, manual control options, analog and digital external triggering,
and watchdog timer. Custom integration services are available upon
request.
For additional information, please contact: info@pressurebiosciences.com

6. 14 Norfolk Avenue
South Easton, MA 02375
508-230-1828 (T)
508-230-1829 (F) V1.081611
www.pressurebiosciences.com