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INFECTIONS OF THE ORAL
MUCOSA
 VIRAL INFECTION
 BACTERIAL INFECTION
 FUNGAL INFECTION
Viral infectious
diseases
Herpes simplex virus(HSV)
A. Primary herpetic gingivostomatitis
(type I H.S.V)
In a person without circulating
antibodies. It’s developed in children and
young adult, rarely in children under 6
months and mainly transmitted by saliva,
incubation period is 5 days.
In the oral cavity is characterized by
multiple vesicular eruptions located in
the all attached oral mucosa, gingival
and movable mucosa, chiefly lips.
Buccal mucosa, pharynx and tonsils
may be involved .
Histologically
intraepithelial vesicles formations
with necrotic exudates and neutrophil
infiltrate accompanied by epithelial
cells showing nuclear ballooning
degeneration.
Treatment
supported care consist of the
prescribing a soft diet, analgesic to
reduce pain and fever with antibiotic
to prevent secondary infection,
soothing mouth wash to wet the
lesion.
B. Secondary herpes simplex infection:
1.Recurrent (Herpes Labialis)
Occurs mostly on the firmly attached
mucosa such as hard palate and attached
gingiva and not movable mucosa.
Heals in 10 days and no treatment is
applied, with reassurance of patient.
2. Herpetic whitlow infection:
is viral dermatitis of finger and also called
terminal pulp infection.
Varicella-zoster infection
• Primary Varicella zoster(chicken pox)
It’s an acute infectious viral disease
the incubation period last for 2-5 weeks,
appears as vesicles with an erythematous
area on boundary and are extremely pruritic,
fever and mild generalized lymphadenopathy
are also present.
Resolved within 4-8 days.
• Secondary varicella zoster infection
along the peripheral nervous system
commonly from dorsal root ganglia.
It starts as painful vesicular eruption on
skin and also may affect oral cavity when
the trigeminal ganglia is infected with
varicella.
Patient gets malaise, fever and enlarged
lymph node at area and runs in a course of
about 2 weeks.
Herpangina
Viral disease caused by “coxsackie
group A virus”
there will be fever and ill-feeling
followed by vesicle rupture, lesion
occurs mainly in soft palate and
tonsilar area.
The disease run a course of (7-10)
days.
Hand-foot &mouth disease
is a highly contagious viral infection
The virus is transferred from one
individual to another through
airborne spread or fecal-oral
contamination.
Clinical Features:
about 90% affects children younger than 5
years of age. After a short incubation
period, the condition resolves
spontaneously in 1 to 2 weeks.
Signs and symptoms are usually mild to
moderate in intensity and include low-grade
fever, malaise, lymphadenopathy, and sore
mouth.
Pain from oral lesions is often the
patient's chief complaint.
Measles
a highly contagious viral infection caused by
a member of the paramyxovirus family.
Typically, oral eruptions consist of early
pinpoint elevations over the soft palate that
combines with ultimate involvement of the
pharynx with bright erythema.
German measles share some clinical features
with measles, such as fever, respiratory
symptoms
Clinical Featurs:
After an incubation period of 7 to 10 days,
prodromal symptoms of fever, malaise,
conjunctivitis, photophobia, and cough
develop.
In 1 to 2 days small erythematous macules
with white necrotic centers appear in the
buccal mucosa, these lesion spots, known as
Koplik's spots. precede the skin rash by 1
to 2 days.
HUMAN IMMUNODEFICIENCY
VIRUS INFECTION (HIV)
is transmitted by exchange of blood or
body fluids principally through sexual
contact. The injection of blood or from
mother to child.
Transmission of the virus may be
followed by infection which is detected
by the appearance of HIV antibodies in
the blood.
This generally occurs within 3
months of exposure. A few patients
have an acute HIV infection at this
time, the clinical features of which
include pyrexia, skin rash, headache,
diarrhea, sore throat, and erythema of
the buccal and palatal mucosa.
EXPOSURE TO INFECTION
INFECTION NO INFECTION
INFECTION
HIV SEROPOSITIVE
asymptomatic
ACUTE HIV INFECTION
Pyrexia,skin rash,headache
,diarrhoea,sore throat
&erythema of buccal&palatal
mucosa
HIV SEROPOSITIVE
asymptomatic
PGL ARC
l.Adenopathy p.pyrexia
Diarr.,weight loss
Fatique &malaise
AIDS
Kaposi sarcoma
Kaposi Sarcoma. Classic Kaposi sarcoma in an
older man presenting as multiple purple macules
and plaques on the lower leg.

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Infection of oral mucosa

  • 1. INFECTIONS OF THE ORAL MUCOSA  VIRAL INFECTION  BACTERIAL INFECTION  FUNGAL INFECTION
  • 3. Herpes simplex virus(HSV) A. Primary herpetic gingivostomatitis (type I H.S.V) In a person without circulating antibodies. It’s developed in children and young adult, rarely in children under 6 months and mainly transmitted by saliva, incubation period is 5 days.
  • 4. In the oral cavity is characterized by multiple vesicular eruptions located in the all attached oral mucosa, gingival and movable mucosa, chiefly lips. Buccal mucosa, pharynx and tonsils may be involved .
  • 5.
  • 6.
  • 7.
  • 8. Histologically intraepithelial vesicles formations with necrotic exudates and neutrophil infiltrate accompanied by epithelial cells showing nuclear ballooning degeneration.
  • 9.
  • 10.
  • 11. Treatment supported care consist of the prescribing a soft diet, analgesic to reduce pain and fever with antibiotic to prevent secondary infection, soothing mouth wash to wet the lesion.
  • 12. B. Secondary herpes simplex infection: 1.Recurrent (Herpes Labialis) Occurs mostly on the firmly attached mucosa such as hard palate and attached gingiva and not movable mucosa. Heals in 10 days and no treatment is applied, with reassurance of patient. 2. Herpetic whitlow infection: is viral dermatitis of finger and also called terminal pulp infection.
  • 13.
  • 14.
  • 15.
  • 16. Varicella-zoster infection • Primary Varicella zoster(chicken pox) It’s an acute infectious viral disease the incubation period last for 2-5 weeks, appears as vesicles with an erythematous area on boundary and are extremely pruritic, fever and mild generalized lymphadenopathy are also present. Resolved within 4-8 days.
  • 17. • Secondary varicella zoster infection along the peripheral nervous system commonly from dorsal root ganglia. It starts as painful vesicular eruption on skin and also may affect oral cavity when the trigeminal ganglia is infected with varicella. Patient gets malaise, fever and enlarged lymph node at area and runs in a course of about 2 weeks.
  • 18.
  • 19.
  • 20.
  • 21. Herpangina Viral disease caused by “coxsackie group A virus” there will be fever and ill-feeling followed by vesicle rupture, lesion occurs mainly in soft palate and tonsilar area. The disease run a course of (7-10) days.
  • 22. Hand-foot &mouth disease is a highly contagious viral infection The virus is transferred from one individual to another through airborne spread or fecal-oral contamination.
  • 23. Clinical Features: about 90% affects children younger than 5 years of age. After a short incubation period, the condition resolves spontaneously in 1 to 2 weeks. Signs and symptoms are usually mild to moderate in intensity and include low-grade fever, malaise, lymphadenopathy, and sore mouth. Pain from oral lesions is often the patient's chief complaint.
  • 24. Measles a highly contagious viral infection caused by a member of the paramyxovirus family. Typically, oral eruptions consist of early pinpoint elevations over the soft palate that combines with ultimate involvement of the pharynx with bright erythema. German measles share some clinical features with measles, such as fever, respiratory symptoms
  • 25. Clinical Featurs: After an incubation period of 7 to 10 days, prodromal symptoms of fever, malaise, conjunctivitis, photophobia, and cough develop. In 1 to 2 days small erythematous macules with white necrotic centers appear in the buccal mucosa, these lesion spots, known as Koplik's spots. precede the skin rash by 1 to 2 days.
  • 26. HUMAN IMMUNODEFICIENCY VIRUS INFECTION (HIV) is transmitted by exchange of blood or body fluids principally through sexual contact. The injection of blood or from mother to child. Transmission of the virus may be followed by infection which is detected by the appearance of HIV antibodies in the blood.
  • 27. This generally occurs within 3 months of exposure. A few patients have an acute HIV infection at this time, the clinical features of which include pyrexia, skin rash, headache, diarrhea, sore throat, and erythema of the buccal and palatal mucosa.
  • 29. INFECTION HIV SEROPOSITIVE asymptomatic ACUTE HIV INFECTION Pyrexia,skin rash,headache ,diarrhoea,sore throat &erythema of buccal&palatal mucosa
  • 30. HIV SEROPOSITIVE asymptomatic PGL ARC l.Adenopathy p.pyrexia Diarr.,weight loss Fatique &malaise AIDS
  • 31.
  • 32.
  • 34. Kaposi Sarcoma. Classic Kaposi sarcoma in an older man presenting as multiple purple macules and plaques on the lower leg.