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1
Introduction
• Human skeleton initially cartilages and fibrous membranes
• Hyaline cartilage is the most abundant cartilage
• By age 25 the skeleton is completely hardened
• 206 bones make up the adult skeleton (20% of body
mass)
• 80 bones of the axial skeleton
• 126 bones of the appendicular skeleton
2
Bone Classification
• Bone Classification:
• Long Bones
• Short Bones
• Sesamoid Bones
• Flat Bones
• Irregular Bones
• Wormian Bones
(sutural)
(a) (e)
(b)
(c)
(d)
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Classification of Bones
Slide 5.4a
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Long bones
Typically longer than wide
Have a shaft with heads at both ends
Contain mostly compact bone
• Examples: Femur, humerus
Classification of Bones
Slide 5.4b
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Short bones
Generally cube-shape
Contain mostly spongy bone
Examples: Carpals, tarsals
Classification of Bones on the
Basis of Shape
Slide 5.4c
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 5.1
Classification of Bones
Slide 5.5a
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Flat bones
Thin and flattened
Usually curved
Thin layers of compact bone around a layer
of spongy bone
Examples: Skull, ribs, sternum
Classification of Bones
Slide 5.5b
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Irregular bones
Irregular shape
Do not fit into other bone classification
categories
Example: Vertebrae and hip
Classification of Bones on the
Basis of Shape
Slide 5.5c
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 5.1
9
Parts of a Long Bone
• Epiphysis
• Distal
• Proximal
• Diaphysis
• Metaphysis
• Compact bone
• Spongy bone
• Articular cartilage
• Periosteum
• Endosteum
• Medullary cavity
• Trabeculae
• Bone marrow
• Red marrow and yellow marrow
Femur
Periosteum
Yellow marrow
Medullary cavity
Space containing
red marrow
Spongy bone
Compact bone
Articular cartilage
Epiphyseal plates
Proximal
epiphysis
Distal
epiphysis
Diaphysis
Endosteum
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10
Microscopic Structure
• Bone cells are called osteocytes
• in a lacuna
• Osteocytes transport nutrients and wastes by
cellular processes in canaliculi
• The extracellular matrix of bone is largely collagen
and inorganic salts
• Collagen gives bone resilience & strength
• Inorganic salts make bone hard
11
Compact Bone
• Osteon
aka Haversian System
• Central canal
• Perforating canal aka
Volkmann’s canal
• Osteocytes
• Lamellae
• Lacunae
• Bone matrix
• Canaliculi
Nerve
Osteon
Nerve
Nerve
Canaliculus
Osteocyte
Periosteum
Endosteum
Trabeculae
Pores
Bone matrix
Blood
vessels
Compact
bone
Lacuna
(space)
Blood
vessels
Perforating
canal
Central canal
containing blood
vessels and nerves
Central
canal
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Microscopic Anatomy of Bone
Slide
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 5.3
Microscopic Anatomy of Bone
Slide
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Lacunae
 Cavities containing
bone cells
(osteocytes)
 Arranged in
concentric rings
 Lamellae
 Rings around the
central canal
 Sites of lacunae Figure 5.3
Microscopic Anatomy of Bone
Slide
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Canaliculi
Tiny canals
Radiate from the
central canal to
lacunae
Form a transport
system
Figure 5.3
15
Spongy Bone
• Spongy bone is aka cancellous bone
(a)
(c)
Spongy bone Compact bone
(b)
Spongy
bone
Compact
bone
Remnant of
epiphyseal plate
Spongy
bone
Compact
bone
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a: Š Ed Reschke; b,c: Courtesy of John W. Hole, Jr.
16
Bone Development
and Growth
• Parts of the skeletal system begin to develop
during the first few weeks of prenatal development
• Bones replace existing connective tissue in one of
two ways:
• As intramembranous bones
• As endchondral bones
17
Intramembranous Bones
• Intramembranous Bones
• These bones originate within sheetlike layers of
connective tissues
• They are the broad, flat bones
• Skull bones (except mandible)
• Are known as intramembranous bones
18
Endochondral Bones
• Endochondral Bones
• Bones begin as hyaline cartilage
• Form models for future bones
• These are most bones of the skeleton
• Are known as endochondral bones
19
Endochondral Ossification
• Hyaline cartilage model
• Primary ossification center
• Secondary ossification centers
• Epiphyseal plate
• Osteoblasts vs. osteoclasts
(b) (c) (d) (e) (f)
(a)
Cartilaginous
model
Calcified
cartilage
Articular
cartilage
Developing
periosteum
Compact bone
developing
Primary
ossification
center
Medullary
cavity
Medullary
cavity
Medullary
cavity
Secondary
ossification
center
Secondary
ossification
center
Blood
vessel
Epiphyseal
plate
Remnant of
epiphyseal
plate
Remnants of
epiphyseal
plates
Epiphyseal
plates
Compact
bone
Spongy
bone
Articular
cartilage
Spongy
bone
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20
Growth at the Epiphyseal Plate
• First layer of cells
• Closest to the end of
epiphysis
• Resting cells
• Anchors epiphyseal plate
to epiphysis
• Zone of resting cartilage
• Second layer of cells
• Many rows of young
cells
• Undergoing mitosis
• zone of proliferating
cartilage
1
2
3
4
(a) (b)
Bone tissue
of epiphysis
Zone of
resting
cartilage
Zone of
proliferating
cartilage
Zone of
hypertrophic
cartilage
Zone of
calcified
cartilage
Ossified
bone of
diaphysis
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b: Š The McGraw-Hill Companies, Inc./Al Telser, photographer
21
Growth at the Epiphyseal Plate
• Third layer of cells
• Older cells
• Left behind when new
cells appear
• Cells enlarging and
becoming calcified
• zone of hypertrophic
cartilage
• Fourth layer of cells
• Thin
• Dead cells
• Calcified extracellular
matrix
• zone of calcified
cartilage
1
2
3
4
(a) (b)
Bone tissue
of epiphysis
Zone of
resting
cartilage
Zone of
proliferating
cartilage
Zone of
hypertrophic
cartilage
Zone of
calcified
cartilage
Ossified
bone of
diaphysis
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
b: Š The McGraw-Hill Companies, Inc./Al Telser, photographer
22
Homeostasis of Bone Tissue
• Bone Resorption – action of osteoclasts and parathyroid
hormone aka parathormone aka PTH
• Bone Deposition – action of osteoblasts and calcitonin
• Occurs by direction of the thyroid and parathyroid glands
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Š Biophoto Associates/Photo Researchers, Inc.
Developing
medullary
cavity
Osteoclast
23
Factors Affecting Bone
Development, Growth and Repair
• Deficiency of Vitamin A – retards bone development
• Deficiency of Vitamin C – results in fragile bones
• Deficiency of Vitamin D – rickets, osteomalacia
• Insufficient Growth Hormone – dwarfism
• Excessive Growth Hormone – gigantism, acromegaly
• Insufficient Thyroid Hormone – delays bone growth
• Sex Hormones – promote bone formation; stimulate ossification
of epiphyseal plates
• Physical Stress – stimulates bone growth
24
Bone Function
• Bones shape, support, and protect body structures
25
Support, Protection,
and Movement
• Support, Movement & Protection
• Gives shape to head, etc.
• Supports body’s weight
• Protects lungs, etc.
• Bones and muscles interact
• When limbs or body parts move
26
Blood Cell Formation
• Blood Cell Formation
• Also known as hematopoiesis
• Occurs in the red bone marrow
27
Inorganic Salt Storage
• Inorganic Salt Storage
• Calcium
• Phosphate
• Magnesium
• Sodium
• Potassium
28
Skeletal Organization
• The actual number of bones in the human skeleton
varies from person to person
• Typically there are about 206 bones
• For convenience the skeleton is divided into the:
• Axial skeleton
• Appendicular skeleton
29
Divisions of the Skeleton
• Axial Skeleton
• Skull
• Spine
• Rib cage
• Appendicular Skeleton
• Upper limbs
• Lower limbs
• Shoulder girdle
• Pelvic girdle
Hyoid
Cranium
Face
Clavicle
Scapula
Sternum
Ribs
Humerus
Ulna
Hip
bone
Radius
Femur
Patella
Tibia
Fibula
Tarsals
Metatarsals
Phalanges
Phalanges
Skull
Vertebral
column
Vertebral
column
Sacrum
Coccyx
Carpals
Metacarpals
(a) (b)
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30
Skull
• Is composed of the cranium (brain case) and the
facial bones
31
Cranium
• Frontal Bone (1)
• Forehead
• Roof of nasal cavity
• Roofs of orbits
• Frontal sinuses
• Supraorbital foramen
• Coronal suture
Parietal bone
Frontal bone
Coronal suture
Lacrimal bone
Ethmoid bone
Squamous suture
Sphenoid bone
Temporal bone
Perpendicular plate
of the ethmoid bone
Infraorbital foramen
Vomer bone
Mandible
Supraorbital foramen
Nasal bone
Sphenoid bone
Middle nasal concha
of the ethmoid bone
Inferior nasal concha
Maxilla
Mental foramen
Zygomatic bone
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32
Cranium
• Parietal Bones (2)
• Side walls of cranium
• Roof of cranium
• Sagittal suture
Coronal suture
Frontal bone
Sphenoid bone
Ethmoid bone
Lacrimal bone
Nasal bone
Zygomatic bone
Maxilla
Mental foramen
Mandible
Coronoid process
Styloid process
Mandibular condyle
Mastoid process
External acoustic meatus Temporal process
of zygomatic bone
Zygomatic process
of temporal bone
Occipital bone
Temporal bone
Parietal bone
Lambdoid suture
Squamous suture
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33
Cranium
• Occipital Bone (1)
• Back of skull
• Base of cranium
• Foramen magnum
• Occipital condyles
• Lambdoidal suture
Zygomatic bone
Palatine process of maxilla
Palatine bone
Occipital bone
Foramen magnum
Lambdoid suture
Zygomatic arch
Mandibular fossa
Styloid process
Occipital condyle
External acoustic meatus
Sphenoid bone
Vomer bone
Temporal bone
Mastoid foramen
Frontal bone
Median palatine suture
Incisive foramen
Greater palatine foramen
Stylomastoid foramen
Foramen spinosum
Carotid canal
Jugular foramen
Foramen ovale
Foramen lacerum
Condylar canal
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34
Cranium
• Temporal Bones (2)
• Side walls of cranium
• Floor of cranium
• Floors and sides of orbits
• Squamous suture
• External acoustic meatus
• Mandibular fossa
• Mastoid process
• Styloid process
• Zygomatic process
Coronal suture
Frontal bone
Sphenoid bone
Ethmoid bone
Lacrimal bone
Nasal bone
Zygomatic bone
Maxilla
Mental foramen
Mandible
Coronoid process
Styloid process
Mandibular condyle
Mastoid process
External acoustic meatus
Temporal process
of zygomatic bone
Zygomatic process
of temporal bone
Occipital bone
Temporal bone
Parietal bone
Lambdoid suture
Squamous suture
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35
Cranium
• Sphenoid Bone (1)
• Base of cranium
• Sides of skull
• Floors and sides
of orbits
• Sella turcica
• Sphenoid sinuses
Transverse section
Lesser wing
Optic canal
Greater
wing
Sella turcica Foramen ovale
Foramen spinosum
Foramen rotundum
Lesser wing
Greater wing
Superior
orbital fissure
Foramen
rotundum
Lateral pterygoid plate
Medial pterygoid plate
(b)
(a)
36
Cranium
• Ethmoid Bone (1)
• Roof and walls of nasal cavity
• Floor of cranium
• Wall of orbits
• Cribiform plates
• Perpendicular plate
• Superior and middle
nasal conchae
• Ethmoid sinuses
• Crista galli
Transverse section
Crista galli
Orbital
surface
Ethmoidal
sinuses
Cribriform
plate
Crista galli
Perpendicular
plate
Superior
nasal concha
Middle nasal
concha
Perpendicular
plate
(a) (b)
37
Facial Skeleton
• Maxillary Bones (2)
• Upper jaw
• Anterior roof of mouth
• Floors of orbits
• Sides of nasal cavity
• Floors of nasal cavity
• Alveolar processes
• Maxillary sinuses
• Palatine process
Coronal suture
Frontal bone
Sphenoid bone
Ethmoid bone
Lacrimal bone
Nasal bone
Zygomatic bone
Maxilla
Mental foramen
Mandible
Coronoid process
Styloid process
Mandibular condyle
Mastoid process
External acoustic meatus
Temporal process
of zygomatic bone
Zygomatic process
of temporal bone
Occipital bone
Temporal bone
Parietal bone
Lambdoid suture
Squamous suture
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38
Facial Skeleton
Frontal sinus
Ethmoidal sinuses
Sphenoidal sinus
Maxillary sinus
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39
Facial Skeleton
• Palatine Bones (2)
• ‘L’ shaped bones located
behind the maxillae
• Posterior section of hard
palate
• Floor of nasal cavity
• Lateral walls of
nasal cavity
Coronal section
Horizontal portion
Perpendicular
portion
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40
Facial Skeleton
• Zygomatic Bones (2)
• Prominences of cheeks
• Lateral walls of orbits
• Floors of orbits
• Temporal process
Coronal suture
Frontal bone
Sphenoid bone
Ethmoid bone
Lacrimal bone
Nasal bone
Zygomatic bone
Maxilla
Mental foramen
Mandible
Coronoid process
Styloid process
Mandibular condyle
Mastoid process
External acoustic meatus
Temporal process
of zygomatic bone
Zygomatic process
of temporal bone
Occipital bone
Temporal bone
Parietal bone
Lambdoid suture
Squamous suture
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41
Facial Skeleton
• Lacrimal Bones (2)
• Medial walls of orbits
• Groove from orbit to nasal
cavity
• Nasal Bones (2)
• Bridge of nose
Coronal suture
Frontal bone
Sphenoid bone
Ethmoid bone
Lacrimal bone
Nasal bone
Zygomatic bone
Maxilla
Mental foramen
Mandible
Coronoid process
Styloid process
Mandibular condyle
Mastoid process
External acoustic meatus
Temporal process
of zygomatic bone
Zygomatic process
of temporal bone
Occipital bone
Temporal bone
Parietal bone
Lambdoid suture
Squamous suture
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42
Facial Skeleton
• Vomer Bone (1)
• Inferior portion of nasal
septum
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Coronal suture
Frontal bone
Nasal bone
Palatine bone
Vomer bone
Alveolar processes
Inferior nasal concha
Maxilla
Palatine process
of maxilla
Styloid process
Sphenoidal sinus
Mandible
Perpendicular plate
(nasal septum)
Frontal sinus
Crista galli
Cribriform plate
Foramen magnum
Jugular foramen
Internal acoustic meatus
Sella turcica
Occipital bone
Parietal bone
Temporal bone
Lambdoid suture
Squamous suture
Sphenoid bone
Hypoglossal canal
Mastoid process
Ethmoid
bone
43
Facial Skeleton
• Inferior Nasal Conchae (2)
• Extend from lateral
walls of nasal cavity
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Coronal suture
Frontal bone
Nasal bone
Palatine bone
Vomer bone
Alveolar processes
Inferior nasal concha
Maxilla
Palatine process
of maxilla
Styloid process
Sphenoidal sinus
Mandible
Perpendicular plate
(nasal septum)
Frontal sinus
Crista galli
Cribriform plate
Foramen magnum
Jugular foramen
Internal acoustic meatus
Sella turcica
Occipital bone
Parietal bone
Temporal bone
Lambdoid suture
Squamous suture
Sphenoid bone
Hypoglossal canal
Mastoid process
Ethmoid
bone
44
Facial Skeleton
• Mandible Bone (1)
• Lower jaw
• Body
• Ramus
• Mandibular condyle
• Coronoid process
• Alveolar process
• Mandibular foramen
• Mental foramen
Coronoid
process
Mandibular
foramen Mandibular condyle
Ramus
Alveolar
border
Mental foramen
Body
Body Alveolar
arch
Mandibular
foramen
Coronoid process
(a)
(b)
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45
Infantile Skull
• Fontanels – fibrous membranes
(b)
Anterior fontanel
Posterior fontanel
Frontal bone
Frontal suture
(metopic suture)
Sagittal suture
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46
Vertebral Column
• The vertebral column, or spinal column, consists of
many vertebrae separated by cartilaginous intervertebral
discs.
47
Vertebral Column
• Cervical vertebrae (7)
• Thoracic vertebrae (12)
• Lumbar vertebrae (5)
• Sacral (4-5 fused segments)
• Sacrum is fused bone
• Coccygeal (3-4 fused segments)
• Coccyx is fused bone
(b)
(a)
Cervical
curvature
Thoracic
curvature
Lumbar
curvature
Lumbar
vertebrae
Thoracic
vertebrae
Cervical
vertebrae
Sacral
curvature
Vertebra
prominens
Rib facet
Intervertebral
Intervertebral
foramina
Sacrum
Coccyx
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48
Vertebral Column
• Cervical curvature
• Thoracic curvature
• Lumbar curvature
• Sacral curvature
• Rib facets
• Vertebral prominens
• Intervertebral discs (IVD)
• Intervertebral foramina (IVF)
(b)
(a)
Cervical
curvature
Thoracic
curvature
Lumbar
curvature
Lumbar
vertebrae
Thoracic
vertebrae
Cervical
vertebrae
Sacral
curvature
Vertebra
prominens
Rib facet
Intervertebral
Intervertebral
foramina
Sacrum
Coccyx
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49
Typical Vertebrae
• Includes the following parts:
• Vertebral body
• Pedicles
• Lamina
• Spinous process
• Transverse processes
• Vertebral foramen
• Facets
50
Cervical Vertebrae
• Atlas – 1st; supports head
• Axis – 2nd; dens pivots to turn
head
• Transverse foramina
• Bifid spinous processes
• Vertebral prominens – useful
landmark
(b) (c)
(a)
Anterior
Posterior
Atlas
Axis
Body
Dens (odontoid
process)
Spinous process
Dens
Inferior articular
process
Facet that articulates
with dens (odontoid process)
of axis
Facet that articulates
with occipital condyle
Spinous
process
Anterior articular
facet for atlas
Transverse
foramen
Transverse
process
Superior
articular facet
Vertebral
foramen
Transverse
process
Transverse
foramen
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51
Thoracic Vertebrae
Body
Superior
articular
process
Spinous
process
Transverse
process
Inferior articular
process
Intervertebral
disc
Anterior
Posterior
Body
Pedicle
Vertebral foramen
Superior articular process
Facet for tubercle of rib
Transverse process
Lamina
Spinous process
Inferior articular
process
Intervertebral notch
Body
Pedicle
Superior
articular
process
Transverse
process
Facet for
tubercle of rib
Spinous
process
(a)
(c)
(b)
• Long spinous processes
• Rib facets
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52
Lumbar Vertebrae
• Large bodies
• Thick, short spinous
processes
(c) Lumbar vertebra
Lamina
Pedicle
Body
Vertebral foramen
Spinous process
Superior articular
process
Transverse process
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53
Sacrum
• 4-5 fused segments
• Median sacral crest
• Posterior sacral
foramina
• Posterior wall of pelvic
cavity
• Sacral promontory aka
base
• Area toward coccyx is
the apex
Sacral canal
Tubercle
of median
sacral crest
Auricular
surface
Posterior sacral
foramen
Sacral hiatus
Coccyx
Sacrum
Superior articular process
Sacral promontory
Anterior sacral
foramen
(a) (b)
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54
Coccyx
• Aka tailbone
• 3-4 fused segments
Sacral canal
Tubercle
of median
sacral crest
Auricular
surface
Posterior sacral
foramen
Sacral hiatus
Coccyx
Sacrum
Superior articular process
Sacral promontory
Anterior sacral
foramen
(a) (b)
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
55
Thoracic Cage
• The thoracic cage includes the ribs, the thoracic
vertebrae, the sternum, and the costal cartilages that attach
the ribs to the sternum.
56
Thoracic Cage
• Ribs (12)
• Sternum
• Thoracic vertebrae (12)
• Costal cartilages
• Supports shoulder girdle
and upper limbs
• Protects viscera
• Role in breathing
1
2
3
4
5
6
7
8
9
10
11
12
True ribs
(vertebrosternal
ribs)
Vertebrochondral
ribs
False
ribs
(a)
Floating ribs
(vertebral ribs)
Sternum
Body
Manubrium
Ribs
Costal
cartilage
Xiphoid process
Thoracic vertebra
Clavicular notch
Sternal angle
Jugular notch
(suprasternal notch)
(b)
b: Š Victor B. Eichler, PhD
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57
Ribs
• Humans have 12 pairs of ribs:
• True ribs (7)
• False ribs (5), of which:
• Floating (2)
• There are some anomalies:
• Cervical ribs
• Lumbar ribs
1
2
3
4
5
6
7
8
9
10
11
12
True ribs
(vertebrosternal
ribs)
Vertebrochondral
ribs
False
ribs
(a)
Floating ribs
(vertebral ribs)
Sternum
Body
Manubrium
Ribs
Costal
cartilage
Xiphoid process
Thoracic vertebra
Clavicular notch
Sternal angle
Jugular notch
(suprasternal notch)
(b)
b: Š Victor B. Eichler, PhD
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58
Rib Structure
• Shaft
• Head – posterior end;
articulates with vertebrae
• Tubercle – articulates with
vertebrae
• Costal cartilage – hyaline
cartilage
Anterior end
(sternal end)
Shaft
Facet
Head
Neck
T
ubercle
Facet
Spinous process
Costal groove
Shaft
Anterior end
Head
Tubercle
Neck
(a)
(b)
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59
Sternum
• Three (3) parts of the
sternum:
• Manubrium
• Body
• Xiphoid process
1
2
3
4
5
6
7
8
9
10
11
12
True ribs
(vertebrosternal
ribs)
Vertebrochondral
ribs
False
ribs
(a)
Floating ribs
(vertebral ribs)
Sternum
Body
Manubrium
Ribs
Costal
cartilage
Xiphoid process
Thoracic vertebra
Clavicular notch
Sternal angle
Jugular notch
(suprasternal notch)
(b)
b: Š Victor B. Eichler, PhD
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
60
Pectoral Girdle
• Also known as the
shoulder girdle
• Clavicles
• Scapulae
• Supports upper limbs
• True shoulder joint is
simply the articulation of
the humerus and scapula
Sternum
Costal
cartilage
Rib
Scapula
Humerus
Ulna
Radius
Clavicle
(a)
Coracoid
process
Head of
humerus
Acromion
process
Acromial end
Sternal end
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
61
Clavicles
• Articulate with manubrium
• Articulate with scapulae
(acromion process)
• A-C joint
Sternum
Costal
cartilage
Rib
Scapula
Humerus
Ulna
Radius
Clavicle
(a)
Coracoid
process
Head of
humerus
Acromion
process
Acromial end
Sternal end
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Acromion
process
Coracoid
process
Spine
Glenoid
cavity
Suprascapular
notch
Superior
border
Supra-
glenoid
tubercle
Infra-
glenoid
tubercle
Coracoid
process
Acromion
process
Supraspinous
fossa
Infraspinous
fossa
Glenoid
cavity
Lateral
(axillary) border
Subscapular
fossa
Medial
(vertebral)
border
(a) (b) (c) 62
Scapulae
• Spine
• Supraspinous fossa
• Infraspinous fossa
• Acromion process
• Coracoid process
• Glenoid fossa or cavity
63
Upper Limb
• Humerus
• Radius
• Ulna
(Interosseous membrane)
• Carpals
• Metacarpals
• Phalanges
Olecranon
process
Head of radius
Neck of radius
Ulna
Olecranon
fossa
Carpals
Metacarpals
Phalanges
Humerus
Humerus
Ulna
Ulna
Radius
(c)
(d)
(a) Hand (palm anterior) (b) Hand (palm posterior)
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
d: Š Martin Rotker
64
Humerus
• Head
• Greater tubercle
• Lesser tubercle
• Anatomical neck
• Surgical neck
• Deltoid tuberosity
• Capitulum
• Trochlea
• Coronoid fossa
• Olecranon fossa
Capitulum
Trochlea
Deltoid tuberosity
Head
Lesser tubercle
Greater tubercle Greater tubercle
(a) (b)
Lateral
epicondyle
Coronoid
fossa
Intertubercular
groove
Medial
epicondyle
Olecranon
fossa
Anatomical
neck
Surgical
neck
Lateral
epicondyle
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
65
Radius
• Lateral forearm bone
• Head
• Radial tuberosity
• Styloid process
Styloid process Ulnar notch of radius
Styloid process
Head of ulna
Ulna
Radius
Radial tuberosity
Head of radius
Coronoid process
Trochlear notch Olecranon
process
(b)
(a)
Olecranon
process
Trochlear
notch
Coronoid
process
Radial
notch
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
66
Ulna
• Medial forearm bone
• Trochlear notch
• Olecranon process
• Coronoid process
• Styloid process
Styloid process Ulnar notch of radius
Styloid process
Head of ulna
Ulna
Radius
Radial tuberosity
Head of radius
Coronoid process
Trochlear notch Olecranon
process
(b)
(a)
Olecranon
process
Trochlear
notch
Coronoid
process
Radial
notch
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
67
Wrist and Hand
• Carpal Bones (16 total bones)
• Scaphoid
• Lunate
• Triquetral
• Pisiform
• Hamate
• Capitate
• Trapezoid
• Trapezium
• Metacarpal Bones (10)
• Phalangeal Bones (28)
• Proximal phalanx
• Middle phalanx
• Distal phalanx
Trapezium
Trapezoid
Capitate
Scaphoid
Trapezium
(a) (b)
Trapezoid
Capitate
Scaphoid Ulna
Radius
Lunate
Hamate
Triquetrum
Pisiform
Phalanges
5
5
4
4 3
3
2
2
1
1
Distal
phalanx
Middle
phalanx
Proximal
phalanx
Metacarpals
(metacarpus)
Carpals
(carpus)
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
68
Pelvic Girdle
• Coxal Bones (2)
• Supports trunk of body
• Protects viscera
• Forms pelvic cavity
Sacrum
Sacral promontory
Sacroiliac joint
Acetabulum
Pubis
Symphysis
pubis
(a)
Pubic arch
Ischium
Pubic tubercle
Ilium
Obturator foramen
Ischium
Coccyx
Sacral hiatus
Sacrum
(b)
Ilium
Sacral canal
Pubis
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
(c)
c: Š Martin Rotker
69
Hip Bones
• Also known as the coxae:
• Acetabulum
• There are three (3)
bones:
1. Ilium
• Iliac crest
• Iliac spines
• Greater sciatic notch
2. Ischium
• Ischial spines
• Lesser sciatic notch
• Ischial tuberosity
3. Pubis
• Obturator foramen
• Symphysis pubis
• Pubic arch
Iliac crest
Iliac crest
Iliac fossa
Ilium
Ilium
Ischium
Ischium
Pubis
Pubis
Ischial spine
Obturator foramen
Acetabulum
Pubic crest
Pubic tubercle
(b)
(a)
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Anterior
superior
iliac spine
Anterior
inferior
iliac spine
Posterior
superior
iliac spine
Posterior
inferior
iliac spine
Greater
sciatic notch
Lesser
sciatic notch
Ischial
tuberosity
Obturator
foramen
70
Greater and Lesser Pelves
• Greater Pelvis
• Lumbar vertebrae
posteriorly
• Iliac bones laterally
• Abdominal wall
anteriorly
• Lesser Pelvis
• Sacrum and coccyx
posteriorly
• Lower ilium, ischium, and
pubic bones laterally and
anteriorly
Sacral promontory
Flared ilium
Pelvic brim
Symphysis pubis
Pubic arch
Pubic arch
(a) Female pelvis
(b) Male pelvis
Sacral promontory
Sacral curvature
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
71
Differences Between
Male Female Pelves
• Female pelvis
• Iliac bones more flared
• Broader hips
• Pubic arch angle greater
• More distance between ischial
spines and ischial tuberosities
• Sacral curvature shorter and
flatter
• Lighter bones
• Why?
Sacral promontory
Flared ilium
Pelvic brim
Symphysis pubis
Pubic arch
Pubic arch
(a) Female pelvis
(b) Male pelvis
Sacral promontory
Sacral curvature
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
72
Lower Limb
• Femur
• Patella
• Tibia
• Fibula
• Tarsals
• Metatarsals
• Phalanges
Metatarsals
Fibula
Tibia
Tibia
Patella
Femur
Fibula
(c) Lateral view
Fibula
Tibia
Lateral
condyle
(d) Posterior view
(b)
Medial
condyle
Femur
Tarsals
Phalanges
Femur
Patella
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
73
Femur
• Longest bone of body
• Head
• Fovea capitis
• Neck
• Greater trochanter
• Lesser trochanter
• Linea aspera
• Condyles
• Epicondyles
Neck Head
Fovea capitis
(a) (b)
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Lateral
condyle
Medial
condyle
Intercondylar
fossa
Medial
epicondyle
Patellar
surface
Lateral
epicondyle
Greater
trochanter Gluteal
tuberosity
Lesser
trochanter
Linea
aspera
74
Patella
• Aka kneecap
• Anterior surface of the knee
joint
• Flat sesamoid bone located
in the quadriceps tendon
Metatarsals
Fibula
Tibia
Tibia
Patella
Femur
Fibula
(c) Lateral view
Fibula
Tibia
Lateral
condyle
(d) Posterior view
(b)
Medial
condyle
Femur
Tarsals
Phalanges
Femur
Patella
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
75
Tibia
• Aka shin bone
• Medial to fibula
• Condyles
• Tibial tuberosity
• Anterior crest
• Makes the medial malleolus
Tibia
Fibula
Medial
malleolus
Tibial
tuberosity
Anterior
crest
Medial
condyle
Intercondylar
eminence
Lateral
malleolus
Lateral
condyle
Head of
fibula
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
76
Fibula
• Lateral to tibia
• Long, slender
• Head
• Makes the lateral malleolus
• Non-weight bearing
Tibia
Fibula
Medial
malleolus
Tibial
tuberosity
Anterior
crest
Medial
condyle
Intercondylar
eminence
Lateral
malleolus
Lateral
condyle
Head of
fibula
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
77
Foot
• Tarsal Bones (14)
• Calcaneus
• Talus
• Navicular
• Cuboid
• Lateral (3rd) cuneiform
• Intermediate (2nd) cuneiform
• Medial (1st) cuneiform
• Metatarsal Bones (10)
• Phalanges (28)
• Proximal
• Middle
• Distal
(b)
Tibia
Fibula
Talus
Navicular
Phalanges
Calcaneus
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Medial
cuneiform
Metatarsals
(metatarsus)
Tarsals
(tarsus)
Calcaneal
tuberosity
78
Foot
Calcaneus
Talus
Navicular
Cuboid
Lateral cuneiform
Intermediate cuneiform
Medial cuneiform
Proximal phalanx
Middle phalanx
Distal phalanx Phalanges
Metatarsals
(metatarsus)
Tarsals
(tarsus)
5
4
3
2 1
(a)
Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
79
Lifespan Changes
• Decrease in height at about age 30
• Calcium levels fall
• Bones become brittle
• Osteoclasts outnumber osteoblasts
• Spongy bone weakens before compact bone
• Bone loss rapid in menopausal women
• Hip fractures common
• Vertebral compression fractures common
80
Joints
Slide 5.43
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Articulations of bones
 Functions of joints
Hold bones together
Allow for mobility
 Ways joints are classified
Functionally
Structurally
Functional Classification of Joints
Slide 5.44
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Synarthroses – immovable joints
 Amphiarthroses – slightly moveable
joints
 Diarthroses – freely moveable joints
Structural Classification of Joints
Slide 5.45
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Fibrous joints
Generally immovable
 Cartilaginous joints
Immovable or slightly moveable
 Synovial joints
Freely moveable
Fibrous Joints
Slide 5.46
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Bones united by fibrous tissue –
synarthrosis or largely immovable.
Figure 5.27d, e
Cartilaginous Joints – mostly
amphiarthrosis
Slide 5.47
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Bones connected by cartilage
 Examples
Pubic
symphysis
Intervertebral
joints
Figure 5.27b, c
Synovial Joints
Slide 5.48
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Articulating
bones are
separated by a
joint cavity
 Synovial fluid
is found in the
joint cavity
Figure 5.27f–h
Features of Synovial Joints-
Diarthroses
Slide 5.49
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Articular cartilage (hyaline cartilage)
covers the ends of bones
 Joint surfaces are enclosed by a fibrous
articular capsule
 Have a joint cavity filled with synovial
fluid
 Ligaments reinforce the joint
Structures Associated with the
Synovial Joint
Slide 5.50
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Bursae – flattened fibrous sacs
 Lined with synovial membranes
 Filled with synovial fluid
 Not actually part of the joint
 Tendon sheath
 Elongated bursa that wraps around a tendon
The Synovial Joint
Slide 5.51
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 5.28
Types of Synovial Joints Based on
Shape
Slide
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 5.29a–c
Types of Synovial Joints Based on
Shape
Slide
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 5.29d–f
Inflammatory Conditions
Associated with Joints
Slide 5.53
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Bursitis – inflammation of a bursa usually
caused by a blow or friction
 Tendonitis – inflammation of tendon sheaths
 Arthritis – inflammatory or degenerative
diseases of joints
 Over 100 different types
 The most widespread crippling disease in the
United States
Clinical Forms of Arthritis
Slide
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Osteoarthritis
 Most common chronic arthritis
 Probably related to normal aging processes
 Rheumatoid arthritis
 An autoimmune disease – the immune system
attacks the joints
 Symptoms begin with bilateral inflammation of
certain joints
 Often leads to deformities
Clinical Forms of Arthritis
Slide
Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Gouty Arthritis
Inflammation of joints is caused by a
deposition of urate crystals from the blood
Can usually be controlled with diet
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bone.ppt

  • 1. 1 Introduction • Human skeleton initially cartilages and fibrous membranes • Hyaline cartilage is the most abundant cartilage • By age 25 the skeleton is completely hardened • 206 bones make up the adult skeleton (20% of body mass) • 80 bones of the axial skeleton • 126 bones of the appendicular skeleton
  • 2. 2 Bone Classification • Bone Classification: • Long Bones • Short Bones • Sesamoid Bones • Flat Bones • Irregular Bones • Wormian Bones (sutural) (a) (e) (b) (c) (d) Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 3. Classification of Bones Slide 5.4a Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Long bones Typically longer than wide Have a shaft with heads at both ends Contain mostly compact bone • Examples: Femur, humerus
  • 4. Classification of Bones Slide 5.4b Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Short bones Generally cube-shape Contain mostly spongy bone Examples: Carpals, tarsals
  • 5. Classification of Bones on the Basis of Shape Slide 5.4c Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 5.1
  • 6. Classification of Bones Slide 5.5a Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Flat bones Thin and flattened Usually curved Thin layers of compact bone around a layer of spongy bone Examples: Skull, ribs, sternum
  • 7. Classification of Bones Slide 5.5b Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Irregular bones Irregular shape Do not fit into other bone classification categories Example: Vertebrae and hip
  • 8. Classification of Bones on the Basis of Shape Slide 5.5c Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 5.1
  • 9. 9 Parts of a Long Bone • Epiphysis • Distal • Proximal • Diaphysis • Metaphysis • Compact bone • Spongy bone • Articular cartilage • Periosteum • Endosteum • Medullary cavity • Trabeculae • Bone marrow • Red marrow and yellow marrow Femur Periosteum Yellow marrow Medullary cavity Space containing red marrow Spongy bone Compact bone Articular cartilage Epiphyseal plates Proximal epiphysis Distal epiphysis Diaphysis Endosteum Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 10. 10 Microscopic Structure • Bone cells are called osteocytes • in a lacuna • Osteocytes transport nutrients and wastes by cellular processes in canaliculi • The extracellular matrix of bone is largely collagen and inorganic salts • Collagen gives bone resilience & strength • Inorganic salts make bone hard
  • 11. 11 Compact Bone • Osteon aka Haversian System • Central canal • Perforating canal aka Volkmann’s canal • Osteocytes • Lamellae • Lacunae • Bone matrix • Canaliculi Nerve Osteon Nerve Nerve Canaliculus Osteocyte Periosteum Endosteum Trabeculae Pores Bone matrix Blood vessels Compact bone Lacuna (space) Blood vessels Perforating canal Central canal containing blood vessels and nerves Central canal Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 12. Microscopic Anatomy of Bone Slide Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 5.3
  • 13. Microscopic Anatomy of Bone Slide Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Lacunae  Cavities containing bone cells (osteocytes)  Arranged in concentric rings  Lamellae  Rings around the central canal  Sites of lacunae Figure 5.3
  • 14. Microscopic Anatomy of Bone Slide Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Canaliculi Tiny canals Radiate from the central canal to lacunae Form a transport system Figure 5.3
  • 15. 15 Spongy Bone • Spongy bone is aka cancellous bone (a) (c) Spongy bone Compact bone (b) Spongy bone Compact bone Remnant of epiphyseal plate Spongy bone Compact bone Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display. a: Š Ed Reschke; b,c: Courtesy of John W. Hole, Jr.
  • 16. 16 Bone Development and Growth • Parts of the skeletal system begin to develop during the first few weeks of prenatal development • Bones replace existing connective tissue in one of two ways: • As intramembranous bones • As endchondral bones
  • 17. 17 Intramembranous Bones • Intramembranous Bones • These bones originate within sheetlike layers of connective tissues • They are the broad, flat bones • Skull bones (except mandible) • Are known as intramembranous bones
  • 18. 18 Endochondral Bones • Endochondral Bones • Bones begin as hyaline cartilage • Form models for future bones • These are most bones of the skeleton • Are known as endochondral bones
  • 19. 19 Endochondral Ossification • Hyaline cartilage model • Primary ossification center • Secondary ossification centers • Epiphyseal plate • Osteoblasts vs. osteoclasts (b) (c) (d) (e) (f) (a) Cartilaginous model Calcified cartilage Articular cartilage Developing periosteum Compact bone developing Primary ossification center Medullary cavity Medullary cavity Medullary cavity Secondary ossification center Secondary ossification center Blood vessel Epiphyseal plate Remnant of epiphyseal plate Remnants of epiphyseal plates Epiphyseal plates Compact bone Spongy bone Articular cartilage Spongy bone Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 20. 20 Growth at the Epiphyseal Plate • First layer of cells • Closest to the end of epiphysis • Resting cells • Anchors epiphyseal plate to epiphysis • Zone of resting cartilage • Second layer of cells • Many rows of young cells • Undergoing mitosis • zone of proliferating cartilage 1 2 3 4 (a) (b) Bone tissue of epiphysis Zone of resting cartilage Zone of proliferating cartilage Zone of hypertrophic cartilage Zone of calcified cartilage Ossified bone of diaphysis Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display. b: Š The McGraw-Hill Companies, Inc./Al Telser, photographer
  • 21. 21 Growth at the Epiphyseal Plate • Third layer of cells • Older cells • Left behind when new cells appear • Cells enlarging and becoming calcified • zone of hypertrophic cartilage • Fourth layer of cells • Thin • Dead cells • Calcified extracellular matrix • zone of calcified cartilage 1 2 3 4 (a) (b) Bone tissue of epiphysis Zone of resting cartilage Zone of proliferating cartilage Zone of hypertrophic cartilage Zone of calcified cartilage Ossified bone of diaphysis Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display. b: Š The McGraw-Hill Companies, Inc./Al Telser, photographer
  • 22. 22 Homeostasis of Bone Tissue • Bone Resorption – action of osteoclasts and parathyroid hormone aka parathormone aka PTH • Bone Deposition – action of osteoblasts and calcitonin • Occurs by direction of the thyroid and parathyroid glands Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Š Biophoto Associates/Photo Researchers, Inc. Developing medullary cavity Osteoclast
  • 23. 23 Factors Affecting Bone Development, Growth and Repair • Deficiency of Vitamin A – retards bone development • Deficiency of Vitamin C – results in fragile bones • Deficiency of Vitamin D – rickets, osteomalacia • Insufficient Growth Hormone – dwarfism • Excessive Growth Hormone – gigantism, acromegaly • Insufficient Thyroid Hormone – delays bone growth • Sex Hormones – promote bone formation; stimulate ossification of epiphyseal plates • Physical Stress – stimulates bone growth
  • 24. 24 Bone Function • Bones shape, support, and protect body structures
  • 25. 25 Support, Protection, and Movement • Support, Movement & Protection • Gives shape to head, etc. • Supports body’s weight • Protects lungs, etc. • Bones and muscles interact • When limbs or body parts move
  • 26. 26 Blood Cell Formation • Blood Cell Formation • Also known as hematopoiesis • Occurs in the red bone marrow
  • 27. 27 Inorganic Salt Storage • Inorganic Salt Storage • Calcium • Phosphate • Magnesium • Sodium • Potassium
  • 28. 28 Skeletal Organization • The actual number of bones in the human skeleton varies from person to person • Typically there are about 206 bones • For convenience the skeleton is divided into the: • Axial skeleton • Appendicular skeleton
  • 29. 29 Divisions of the Skeleton • Axial Skeleton • Skull • Spine • Rib cage • Appendicular Skeleton • Upper limbs • Lower limbs • Shoulder girdle • Pelvic girdle Hyoid Cranium Face Clavicle Scapula Sternum Ribs Humerus Ulna Hip bone Radius Femur Patella Tibia Fibula Tarsals Metatarsals Phalanges Phalanges Skull Vertebral column Vertebral column Sacrum Coccyx Carpals Metacarpals (a) (b) Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 30. 30 Skull • Is composed of the cranium (brain case) and the facial bones
  • 31. 31 Cranium • Frontal Bone (1) • Forehead • Roof of nasal cavity • Roofs of orbits • Frontal sinuses • Supraorbital foramen • Coronal suture Parietal bone Frontal bone Coronal suture Lacrimal bone Ethmoid bone Squamous suture Sphenoid bone Temporal bone Perpendicular plate of the ethmoid bone Infraorbital foramen Vomer bone Mandible Supraorbital foramen Nasal bone Sphenoid bone Middle nasal concha of the ethmoid bone Inferior nasal concha Maxilla Mental foramen Zygomatic bone Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 32. 32 Cranium • Parietal Bones (2) • Side walls of cranium • Roof of cranium • Sagittal suture Coronal suture Frontal bone Sphenoid bone Ethmoid bone Lacrimal bone Nasal bone Zygomatic bone Maxilla Mental foramen Mandible Coronoid process Styloid process Mandibular condyle Mastoid process External acoustic meatus Temporal process of zygomatic bone Zygomatic process of temporal bone Occipital bone Temporal bone Parietal bone Lambdoid suture Squamous suture Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 33. 33 Cranium • Occipital Bone (1) • Back of skull • Base of cranium • Foramen magnum • Occipital condyles • Lambdoidal suture Zygomatic bone Palatine process of maxilla Palatine bone Occipital bone Foramen magnum Lambdoid suture Zygomatic arch Mandibular fossa Styloid process Occipital condyle External acoustic meatus Sphenoid bone Vomer bone Temporal bone Mastoid foramen Frontal bone Median palatine suture Incisive foramen Greater palatine foramen Stylomastoid foramen Foramen spinosum Carotid canal Jugular foramen Foramen ovale Foramen lacerum Condylar canal Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 34. 34 Cranium • Temporal Bones (2) • Side walls of cranium • Floor of cranium • Floors and sides of orbits • Squamous suture • External acoustic meatus • Mandibular fossa • Mastoid process • Styloid process • Zygomatic process Coronal suture Frontal bone Sphenoid bone Ethmoid bone Lacrimal bone Nasal bone Zygomatic bone Maxilla Mental foramen Mandible Coronoid process Styloid process Mandibular condyle Mastoid process External acoustic meatus Temporal process of zygomatic bone Zygomatic process of temporal bone Occipital bone Temporal bone Parietal bone Lambdoid suture Squamous suture Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 35. 35 Cranium • Sphenoid Bone (1) • Base of cranium • Sides of skull • Floors and sides of orbits • Sella turcica • Sphenoid sinuses Transverse section Lesser wing Optic canal Greater wing Sella turcica Foramen ovale Foramen spinosum Foramen rotundum Lesser wing Greater wing Superior orbital fissure Foramen rotundum Lateral pterygoid plate Medial pterygoid plate (b) (a)
  • 36. 36 Cranium • Ethmoid Bone (1) • Roof and walls of nasal cavity • Floor of cranium • Wall of orbits • Cribiform plates • Perpendicular plate • Superior and middle nasal conchae • Ethmoid sinuses • Crista galli Transverse section Crista galli Orbital surface Ethmoidal sinuses Cribriform plate Crista galli Perpendicular plate Superior nasal concha Middle nasal concha Perpendicular plate (a) (b)
  • 37. 37 Facial Skeleton • Maxillary Bones (2) • Upper jaw • Anterior roof of mouth • Floors of orbits • Sides of nasal cavity • Floors of nasal cavity • Alveolar processes • Maxillary sinuses • Palatine process Coronal suture Frontal bone Sphenoid bone Ethmoid bone Lacrimal bone Nasal bone Zygomatic bone Maxilla Mental foramen Mandible Coronoid process Styloid process Mandibular condyle Mastoid process External acoustic meatus Temporal process of zygomatic bone Zygomatic process of temporal bone Occipital bone Temporal bone Parietal bone Lambdoid suture Squamous suture Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 38. 38 Facial Skeleton Frontal sinus Ethmoidal sinuses Sphenoidal sinus Maxillary sinus Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 39. 39 Facial Skeleton • Palatine Bones (2) • ‘L’ shaped bones located behind the maxillae • Posterior section of hard palate • Floor of nasal cavity • Lateral walls of nasal cavity Coronal section Horizontal portion Perpendicular portion Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 40. 40 Facial Skeleton • Zygomatic Bones (2) • Prominences of cheeks • Lateral walls of orbits • Floors of orbits • Temporal process Coronal suture Frontal bone Sphenoid bone Ethmoid bone Lacrimal bone Nasal bone Zygomatic bone Maxilla Mental foramen Mandible Coronoid process Styloid process Mandibular condyle Mastoid process External acoustic meatus Temporal process of zygomatic bone Zygomatic process of temporal bone Occipital bone Temporal bone Parietal bone Lambdoid suture Squamous suture Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 41. 41 Facial Skeleton • Lacrimal Bones (2) • Medial walls of orbits • Groove from orbit to nasal cavity • Nasal Bones (2) • Bridge of nose Coronal suture Frontal bone Sphenoid bone Ethmoid bone Lacrimal bone Nasal bone Zygomatic bone Maxilla Mental foramen Mandible Coronoid process Styloid process Mandibular condyle Mastoid process External acoustic meatus Temporal process of zygomatic bone Zygomatic process of temporal bone Occipital bone Temporal bone Parietal bone Lambdoid suture Squamous suture Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 42. 42 Facial Skeleton • Vomer Bone (1) • Inferior portion of nasal septum Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Coronal suture Frontal bone Nasal bone Palatine bone Vomer bone Alveolar processes Inferior nasal concha Maxilla Palatine process of maxilla Styloid process Sphenoidal sinus Mandible Perpendicular plate (nasal septum) Frontal sinus Crista galli Cribriform plate Foramen magnum Jugular foramen Internal acoustic meatus Sella turcica Occipital bone Parietal bone Temporal bone Lambdoid suture Squamous suture Sphenoid bone Hypoglossal canal Mastoid process Ethmoid bone
  • 43. 43 Facial Skeleton • Inferior Nasal Conchae (2) • Extend from lateral walls of nasal cavity Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Coronal suture Frontal bone Nasal bone Palatine bone Vomer bone Alveolar processes Inferior nasal concha Maxilla Palatine process of maxilla Styloid process Sphenoidal sinus Mandible Perpendicular plate (nasal septum) Frontal sinus Crista galli Cribriform plate Foramen magnum Jugular foramen Internal acoustic meatus Sella turcica Occipital bone Parietal bone Temporal bone Lambdoid suture Squamous suture Sphenoid bone Hypoglossal canal Mastoid process Ethmoid bone
  • 44. 44 Facial Skeleton • Mandible Bone (1) • Lower jaw • Body • Ramus • Mandibular condyle • Coronoid process • Alveolar process • Mandibular foramen • Mental foramen Coronoid process Mandibular foramen Mandibular condyle Ramus Alveolar border Mental foramen Body Body Alveolar arch Mandibular foramen Coronoid process (a) (b) Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 45. 45 Infantile Skull • Fontanels – fibrous membranes (b) Anterior fontanel Posterior fontanel Frontal bone Frontal suture (metopic suture) Sagittal suture Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 46. 46 Vertebral Column • The vertebral column, or spinal column, consists of many vertebrae separated by cartilaginous intervertebral discs.
  • 47. 47 Vertebral Column • Cervical vertebrae (7) • Thoracic vertebrae (12) • Lumbar vertebrae (5) • Sacral (4-5 fused segments) • Sacrum is fused bone • Coccygeal (3-4 fused segments) • Coccyx is fused bone (b) (a) Cervical curvature Thoracic curvature Lumbar curvature Lumbar vertebrae Thoracic vertebrae Cervical vertebrae Sacral curvature Vertebra prominens Rib facet Intervertebral Intervertebral foramina Sacrum Coccyx Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 48. 48 Vertebral Column • Cervical curvature • Thoracic curvature • Lumbar curvature • Sacral curvature • Rib facets • Vertebral prominens • Intervertebral discs (IVD) • Intervertebral foramina (IVF) (b) (a) Cervical curvature Thoracic curvature Lumbar curvature Lumbar vertebrae Thoracic vertebrae Cervical vertebrae Sacral curvature Vertebra prominens Rib facet Intervertebral Intervertebral foramina Sacrum Coccyx Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 49. 49 Typical Vertebrae • Includes the following parts: • Vertebral body • Pedicles • Lamina • Spinous process • Transverse processes • Vertebral foramen • Facets
  • 50. 50 Cervical Vertebrae • Atlas – 1st; supports head • Axis – 2nd; dens pivots to turn head • Transverse foramina • Bifid spinous processes • Vertebral prominens – useful landmark (b) (c) (a) Anterior Posterior Atlas Axis Body Dens (odontoid process) Spinous process Dens Inferior articular process Facet that articulates with dens (odontoid process) of axis Facet that articulates with occipital condyle Spinous process Anterior articular facet for atlas Transverse foramen Transverse process Superior articular facet Vertebral foramen Transverse process Transverse foramen Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 51. 51 Thoracic Vertebrae Body Superior articular process Spinous process Transverse process Inferior articular process Intervertebral disc Anterior Posterior Body Pedicle Vertebral foramen Superior articular process Facet for tubercle of rib Transverse process Lamina Spinous process Inferior articular process Intervertebral notch Body Pedicle Superior articular process Transverse process Facet for tubercle of rib Spinous process (a) (c) (b) • Long spinous processes • Rib facets Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 52. 52 Lumbar Vertebrae • Large bodies • Thick, short spinous processes (c) Lumbar vertebra Lamina Pedicle Body Vertebral foramen Spinous process Superior articular process Transverse process Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 53. 53 Sacrum • 4-5 fused segments • Median sacral crest • Posterior sacral foramina • Posterior wall of pelvic cavity • Sacral promontory aka base • Area toward coccyx is the apex Sacral canal Tubercle of median sacral crest Auricular surface Posterior sacral foramen Sacral hiatus Coccyx Sacrum Superior articular process Sacral promontory Anterior sacral foramen (a) (b) Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 54. 54 Coccyx • Aka tailbone • 3-4 fused segments Sacral canal Tubercle of median sacral crest Auricular surface Posterior sacral foramen Sacral hiatus Coccyx Sacrum Superior articular process Sacral promontory Anterior sacral foramen (a) (b) Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 55. 55 Thoracic Cage • The thoracic cage includes the ribs, the thoracic vertebrae, the sternum, and the costal cartilages that attach the ribs to the sternum.
  • 56. 56 Thoracic Cage • Ribs (12) • Sternum • Thoracic vertebrae (12) • Costal cartilages • Supports shoulder girdle and upper limbs • Protects viscera • Role in breathing 1 2 3 4 5 6 7 8 9 10 11 12 True ribs (vertebrosternal ribs) Vertebrochondral ribs False ribs (a) Floating ribs (vertebral ribs) Sternum Body Manubrium Ribs Costal cartilage Xiphoid process Thoracic vertebra Clavicular notch Sternal angle Jugular notch (suprasternal notch) (b) b: Š Victor B. Eichler, PhD Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 57. 57 Ribs • Humans have 12 pairs of ribs: • True ribs (7) • False ribs (5), of which: • Floating (2) • There are some anomalies: • Cervical ribs • Lumbar ribs 1 2 3 4 5 6 7 8 9 10 11 12 True ribs (vertebrosternal ribs) Vertebrochondral ribs False ribs (a) Floating ribs (vertebral ribs) Sternum Body Manubrium Ribs Costal cartilage Xiphoid process Thoracic vertebra Clavicular notch Sternal angle Jugular notch (suprasternal notch) (b) b: Š Victor B. Eichler, PhD Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 58. 58 Rib Structure • Shaft • Head – posterior end; articulates with vertebrae • Tubercle – articulates with vertebrae • Costal cartilage – hyaline cartilage Anterior end (sternal end) Shaft Facet Head Neck T ubercle Facet Spinous process Costal groove Shaft Anterior end Head Tubercle Neck (a) (b) Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 59. 59 Sternum • Three (3) parts of the sternum: • Manubrium • Body • Xiphoid process 1 2 3 4 5 6 7 8 9 10 11 12 True ribs (vertebrosternal ribs) Vertebrochondral ribs False ribs (a) Floating ribs (vertebral ribs) Sternum Body Manubrium Ribs Costal cartilage Xiphoid process Thoracic vertebra Clavicular notch Sternal angle Jugular notch (suprasternal notch) (b) b: Š Victor B. Eichler, PhD Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 60. 60 Pectoral Girdle • Also known as the shoulder girdle • Clavicles • Scapulae • Supports upper limbs • True shoulder joint is simply the articulation of the humerus and scapula Sternum Costal cartilage Rib Scapula Humerus Ulna Radius Clavicle (a) Coracoid process Head of humerus Acromion process Acromial end Sternal end Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 61. 61 Clavicles • Articulate with manubrium • Articulate with scapulae (acromion process) • A-C joint Sternum Costal cartilage Rib Scapula Humerus Ulna Radius Clavicle (a) Coracoid process Head of humerus Acromion process Acromial end Sternal end Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 62. Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Acromion process Coracoid process Spine Glenoid cavity Suprascapular notch Superior border Supra- glenoid tubercle Infra- glenoid tubercle Coracoid process Acromion process Supraspinous fossa Infraspinous fossa Glenoid cavity Lateral (axillary) border Subscapular fossa Medial (vertebral) border (a) (b) (c) 62 Scapulae • Spine • Supraspinous fossa • Infraspinous fossa • Acromion process • Coracoid process • Glenoid fossa or cavity
  • 63. 63 Upper Limb • Humerus • Radius • Ulna (Interosseous membrane) • Carpals • Metacarpals • Phalanges Olecranon process Head of radius Neck of radius Ulna Olecranon fossa Carpals Metacarpals Phalanges Humerus Humerus Ulna Ulna Radius (c) (d) (a) Hand (palm anterior) (b) Hand (palm posterior) Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display. d: Š Martin Rotker
  • 64. 64 Humerus • Head • Greater tubercle • Lesser tubercle • Anatomical neck • Surgical neck • Deltoid tuberosity • Capitulum • Trochlea • Coronoid fossa • Olecranon fossa Capitulum Trochlea Deltoid tuberosity Head Lesser tubercle Greater tubercle Greater tubercle (a) (b) Lateral epicondyle Coronoid fossa Intertubercular groove Medial epicondyle Olecranon fossa Anatomical neck Surgical neck Lateral epicondyle Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 65. 65 Radius • Lateral forearm bone • Head • Radial tuberosity • Styloid process Styloid process Ulnar notch of radius Styloid process Head of ulna Ulna Radius Radial tuberosity Head of radius Coronoid process Trochlear notch Olecranon process (b) (a) Olecranon process Trochlear notch Coronoid process Radial notch Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 66. 66 Ulna • Medial forearm bone • Trochlear notch • Olecranon process • Coronoid process • Styloid process Styloid process Ulnar notch of radius Styloid process Head of ulna Ulna Radius Radial tuberosity Head of radius Coronoid process Trochlear notch Olecranon process (b) (a) Olecranon process Trochlear notch Coronoid process Radial notch Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 67. 67 Wrist and Hand • Carpal Bones (16 total bones) • Scaphoid • Lunate • Triquetral • Pisiform • Hamate • Capitate • Trapezoid • Trapezium • Metacarpal Bones (10) • Phalangeal Bones (28) • Proximal phalanx • Middle phalanx • Distal phalanx Trapezium Trapezoid Capitate Scaphoid Trapezium (a) (b) Trapezoid Capitate Scaphoid Ulna Radius Lunate Hamate Triquetrum Pisiform Phalanges 5 5 4 4 3 3 2 2 1 1 Distal phalanx Middle phalanx Proximal phalanx Metacarpals (metacarpus) Carpals (carpus) Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 68. 68 Pelvic Girdle • Coxal Bones (2) • Supports trunk of body • Protects viscera • Forms pelvic cavity Sacrum Sacral promontory Sacroiliac joint Acetabulum Pubis Symphysis pubis (a) Pubic arch Ischium Pubic tubercle Ilium Obturator foramen Ischium Coccyx Sacral hiatus Sacrum (b) Ilium Sacral canal Pubis Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display. (c) c: Š Martin Rotker
  • 69. 69 Hip Bones • Also known as the coxae: • Acetabulum • There are three (3) bones: 1. Ilium • Iliac crest • Iliac spines • Greater sciatic notch 2. Ischium • Ischial spines • Lesser sciatic notch • Ischial tuberosity 3. Pubis • Obturator foramen • Symphysis pubis • Pubic arch Iliac crest Iliac crest Iliac fossa Ilium Ilium Ischium Ischium Pubis Pubis Ischial spine Obturator foramen Acetabulum Pubic crest Pubic tubercle (b) (a) Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Anterior superior iliac spine Anterior inferior iliac spine Posterior superior iliac spine Posterior inferior iliac spine Greater sciatic notch Lesser sciatic notch Ischial tuberosity Obturator foramen
  • 70. 70 Greater and Lesser Pelves • Greater Pelvis • Lumbar vertebrae posteriorly • Iliac bones laterally • Abdominal wall anteriorly • Lesser Pelvis • Sacrum and coccyx posteriorly • Lower ilium, ischium, and pubic bones laterally and anteriorly Sacral promontory Flared ilium Pelvic brim Symphysis pubis Pubic arch Pubic arch (a) Female pelvis (b) Male pelvis Sacral promontory Sacral curvature Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 71. 71 Differences Between Male Female Pelves • Female pelvis • Iliac bones more flared • Broader hips • Pubic arch angle greater • More distance between ischial spines and ischial tuberosities • Sacral curvature shorter and flatter • Lighter bones • Why? Sacral promontory Flared ilium Pelvic brim Symphysis pubis Pubic arch Pubic arch (a) Female pelvis (b) Male pelvis Sacral promontory Sacral curvature Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 72. 72 Lower Limb • Femur • Patella • Tibia • Fibula • Tarsals • Metatarsals • Phalanges Metatarsals Fibula Tibia Tibia Patella Femur Fibula (c) Lateral view Fibula Tibia Lateral condyle (d) Posterior view (b) Medial condyle Femur Tarsals Phalanges Femur Patella Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 73. 73 Femur • Longest bone of body • Head • Fovea capitis • Neck • Greater trochanter • Lesser trochanter • Linea aspera • Condyles • Epicondyles Neck Head Fovea capitis (a) (b) Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Lateral condyle Medial condyle Intercondylar fossa Medial epicondyle Patellar surface Lateral epicondyle Greater trochanter Gluteal tuberosity Lesser trochanter Linea aspera
  • 74. 74 Patella • Aka kneecap • Anterior surface of the knee joint • Flat sesamoid bone located in the quadriceps tendon Metatarsals Fibula Tibia Tibia Patella Femur Fibula (c) Lateral view Fibula Tibia Lateral condyle (d) Posterior view (b) Medial condyle Femur Tarsals Phalanges Femur Patella Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 75. 75 Tibia • Aka shin bone • Medial to fibula • Condyles • Tibial tuberosity • Anterior crest • Makes the medial malleolus Tibia Fibula Medial malleolus Tibial tuberosity Anterior crest Medial condyle Intercondylar eminence Lateral malleolus Lateral condyle Head of fibula Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 76. 76 Fibula • Lateral to tibia • Long, slender • Head • Makes the lateral malleolus • Non-weight bearing Tibia Fibula Medial malleolus Tibial tuberosity Anterior crest Medial condyle Intercondylar eminence Lateral malleolus Lateral condyle Head of fibula Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 77. 77 Foot • Tarsal Bones (14) • Calcaneus • Talus • Navicular • Cuboid • Lateral (3rd) cuneiform • Intermediate (2nd) cuneiform • Medial (1st) cuneiform • Metatarsal Bones (10) • Phalanges (28) • Proximal • Middle • Distal (b) Tibia Fibula Talus Navicular Phalanges Calcaneus Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Medial cuneiform Metatarsals (metatarsus) Tarsals (tarsus) Calcaneal tuberosity
  • 78. 78 Foot Calcaneus Talus Navicular Cuboid Lateral cuneiform Intermediate cuneiform Medial cuneiform Proximal phalanx Middle phalanx Distal phalanx Phalanges Metatarsals (metatarsus) Tarsals (tarsus) 5 4 3 2 1 (a) Copyright Š The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
  • 79. 79 Lifespan Changes • Decrease in height at about age 30 • Calcium levels fall • Bones become brittle • Osteoclasts outnumber osteoblasts • Spongy bone weakens before compact bone • Bone loss rapid in menopausal women • Hip fractures common • Vertebral compression fractures common
  • 80. 80
  • 81. Joints Slide 5.43 Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Articulations of bones  Functions of joints Hold bones together Allow for mobility  Ways joints are classified Functionally Structurally
  • 82. Functional Classification of Joints Slide 5.44 Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Synarthroses – immovable joints  Amphiarthroses – slightly moveable joints  Diarthroses – freely moveable joints
  • 83. Structural Classification of Joints Slide 5.45 Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Fibrous joints Generally immovable  Cartilaginous joints Immovable or slightly moveable  Synovial joints Freely moveable
  • 84. Fibrous Joints Slide 5.46 Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Bones united by fibrous tissue – synarthrosis or largely immovable. Figure 5.27d, e
  • 85. Cartilaginous Joints – mostly amphiarthrosis Slide 5.47 Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Bones connected by cartilage  Examples Pubic symphysis Intervertebral joints Figure 5.27b, c
  • 86. Synovial Joints Slide 5.48 Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Articulating bones are separated by a joint cavity  Synovial fluid is found in the joint cavity Figure 5.27f–h
  • 87. Features of Synovial Joints- Diarthroses Slide 5.49 Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Articular cartilage (hyaline cartilage) covers the ends of bones  Joint surfaces are enclosed by a fibrous articular capsule  Have a joint cavity filled with synovial fluid  Ligaments reinforce the joint
  • 88. Structures Associated with the Synovial Joint Slide 5.50 Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Bursae – flattened fibrous sacs  Lined with synovial membranes  Filled with synovial fluid  Not actually part of the joint  Tendon sheath  Elongated bursa that wraps around a tendon
  • 89. The Synovial Joint Slide 5.51 Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 5.28
  • 90. Types of Synovial Joints Based on Shape Slide Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 5.29a–c
  • 91. Types of Synovial Joints Based on Shape Slide Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 5.29d–f
  • 92. Inflammatory Conditions Associated with Joints Slide 5.53 Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Bursitis – inflammation of a bursa usually caused by a blow or friction  Tendonitis – inflammation of tendon sheaths  Arthritis – inflammatory or degenerative diseases of joints  Over 100 different types  The most widespread crippling disease in the United States
  • 93. Clinical Forms of Arthritis Slide Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Osteoarthritis  Most common chronic arthritis  Probably related to normal aging processes  Rheumatoid arthritis  An autoimmune disease – the immune system attacks the joints  Symptoms begin with bilateral inflammation of certain joints  Often leads to deformities
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  • 95.
  • 96. Clinical Forms of Arthritis Slide Copyright Š 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Gouty Arthritis Inflammation of joints is caused by a deposition of urate crystals from the blood Can usually be controlled with diet