Pressure ulcers are localized skin injuries caused by prolonged unrelieved pressure, usually over bony areas. They are staged from 1 to 4 based on the depth of tissue destruction, with stage 1 being non-blanchable erythema and stage 4 extending into muscle, tendon or bone. Stage 2 involves damage to the epidermis and dermis, appearing as a shallow open ulcer. Stage 3 is a full-thickness tissue loss where subcutaneous fat may be visible.