3. • 2013最佳論文獎(全國計算流體力學研討
會)
• 2015 論文獎(中國土木水利工程學會)
• 2015 國家實驗研究院科技貢獻獎
• 2015 鉑金獎(台北國際發明暨技術交易展)
• 2015 資訊月百大創新獎
• 2015 科技部技術移轉貢獻獎
• 2016 台灣生物力學學會年度學術研討會
口頭論文特優獎
• 2017台北星光媒合會『特優奬』
• 2017資訊月百大創新產品獎-創新金質獎
• 2017亞太資通訊科技聯盟大賽(APICTA
Awards) 健康保健類之金牌
獎項
Taiwan: Hsiao Hung Ta, Wang Sheng Chuan, Lin Franco, Lee Lung Cheng,
Yao Chih Min, Chen Ning Hung, Yu Chung Chih, 2015, METHOD AND
COMPUTER FOR AIDING DETERMINATION OF OBSTRUCTIVE SLEEP
APNEA.(Patent NO. ：I413511)
US: Hsiao, Hung Ta, Wang Sheng Chuan, Lin Franco, Lee Lung Cheng, Yao
Chih Min, Chen Ning Hung, Yu Chung Chih, 2015, METHOD AND
COMPUTER FOR AIDING DETERMINATION OF OBSTRUCTIVE SLEEP
APNEA.(Patent NO. ：US 8,929,623 B2)
US: Wen Yi, Chang, Franco, Lin, Lung Cheng, Lee, Hung Ta, Hsiao, Shou I,
Chen, Yu Chi, Sung, Tai Shan, Liao, Chih Yen, Chen, 2014, Method For
Measuring Cracks Remotely and Device Thereof(Patent NO. ： US 8,908,195 B2)
Taiwan: Wen Yi, Chang, Franco, Lin, Lung Cheng, Lee, Hung Ta, Hsiao, Shou
I, Chen, Yu Chi, Sung, Tai Shan, Liao, Chih Yen, Chen, 2014, Method For
Measuring Cracks Remotely and Device Thereof. (Patent NO. ：I482943)
Taiwan: Shou I, Chen, Wang Sheng Chuan, Hung Ta, Hsiao, Lee Lung Cheng,
Ming Hsiao Lee, Yao Chih Min, 2016, Method and Computer For Aiding
Determination of Strength of Patch in Craniofacial Surgery (Patent NO. ：
I549011)
US: Shou I, Chen, Wang Sheng Chuan, Hung Ta, Hsiao, Lee Lung Cheng,
Ming Hsiao Lee, Yao Chih Min, 2014, Method for assisting in determining
strength of fixing craniofacial surgery patch and computer using the same, (Patent
NO. ：US8861825 B2)
Taiwan: Hsiao Hung Ta, Lo Ing-Hsien, 2017, METHOD OF ADJUSTING
SNORING MOUTHPIECE.
專利
4. 領先全球創新技術
1.全球首見結合影像學，計算流體力學與雲端系統的睡眠呼吸產品。
2.創新的睡眠呼吸中止症快速診斷方法。
3.客製化呼吸道自動抓取與3D呼吸道重建。
4. 呼吸道客製化全自動數值模擬計算。
經濟部技術處生醫產業發展資訊服務網-產業動態-國研院新技術 15分鐘測呼吸中止症
專利(台灣和美國)：
Taiwan: Hsiao Hung Ta, Wang Sheng Chuan, Lin Franco, Lee Lung Cheng, Yao Chih Min, Chen Ning Hung, Yu Chung Chih, 2015, METHOD
AND COMPUTER FOR AIDING DETERMINATION OF OBSTRUCTIVE SLEEP APNEA.(Patent NO.：I413511)
US: Hsiao, Hung Ta, Wang Sheng Chuan, Lin Franco, Lee Lung Cheng, Yao Chih Min, Chen Ning Hung, Yu Chung Chih, 2015, METHOD
AND COMPUTER FOR AIDING DETERMINATION OF OBSTRUCTIVE SLEEP APNEA.(Patent NO.：US 8,929,623 B2)
獲獎
1. 2015 國家實驗研究院科技貢獻獎
2. 2015 百大創新獎
3. 2015 科技部技術移轉貢獻獎
呼吸道外型抓
取
3D呼吸道重建 呼吸流體力學
計算
自動化流
程
網
路
電腦斷層影像
醫生
15分
鐘 !!
評估報告
儲存
超級電
腦
43. Soteria OA Solution system
Material Data base
GUI
Digital CraniofacialCFD Module
Meshing Module
CSA Module
1. 提供醫療3D列印檔案
2. 提供3D影像的量測
3. 提供呼吸道呼吸壓力和速度大小
4. 提供止鼾牙套診斷和治療
5. 提供顱顏手術前後評估
6. 提供OSA快速診斷
50. • Snoring is produced by obstruction of air movement during breathing while
sleeping
• OSA is the most common types of sleep apnea, it accounts for 84%* of all sleep
apnea. It is caused by partial or complete obstructed upper airway.
• Snoring during sleep may be the first sign of OSA
Snoring and Obstructive Sleep Apnea (OSA)
*Morgenthaler TI, Kagramanov V, Hanak V, Decker PA. Complex sleep apnea syndrome: is it a unique clinical syndrome?. Sleep. 2006-09, 29 (9): 1203–
9
52. 採用數據分析實現精準醫療的新系統
快速&有效的止鼾牙套治療評估系統
• 發現問題
止鼾牙套：
1. 治療睡眠呼吸中止症的方法。
2. 全世界許多睡眠組織推薦1。
3. 有效治療止鼾和輕度至中度睡
眠呼吸中止症2。
4. 一年內患者治癒率高達70％2。
5. 無已知不良反應3。
止鼾牙套的缺點：
1. 醫師無法判斷止鼾牙套對病患的適用性。
(導致失敗率高達30%)
2. 治療效果需再到睡眠中心做檢查。
(導致患者治療時間拉長)
造成止鼾牙套的治療率下降與治療的不便性
1. American Academy of Dental Sleep Medicine; European Academy of Dental Sleep Medicine; American Academy of Sleep Medicine; Sleep Health Foundation (Australia); Australasian Sleep
Association
2. Ferguson K., Cartwright R., Rogers R., Schmidt-Nowara W. Oral Appliances for Snoring and Obstructive Sleep Apnea: A Review. SLEEP 2006;29(2):244-262
3. Ringqvist M., Walker-Engstro M.L., Tegelberg A., Ringqvist I. Dental and skeletal changes after 4 years of obstructive sleep apnea treatment with a mandibular advancement device: A
prospective, randomized study. Am J Orthod Dentofacial Orthop 2003;124:53-60
56. • 競爭優勢(Advantages)
最先進的止鼾牙套治療評估系統
1. 精準的上呼吸道3D重建技術
2. 先進CFD演算法，取得上呼吸道氣流狀態
3. 大幅節省止鼾牙套病患診斷與治療期程，快速找到潛在適合止
鼾牙套病患
Narrow upper airway Result shows a large pressure difference at the
upper airway; a sign of obstruction Upper airway patent
Result shows no pressure difference, airway is open
64. Method
CBCT scan with 0.6mm slice
CBCT scan with a bite fork
Comparison between two scans:
1. Normal bite 2. With a bite fork
1 2
1
2
65. Method
CBCT images 3D Reconstruction Mesh
2. Reconstruct OSA patient’s upper airway from the 2D CBCT images into 3D model
66. Method
3. Computational Fluid Dynamics to simulate and compare the two airway flow
field characteristics (e.g. pressure and velocity)
1 2
Pressure distribution
1 2
Velocity distribution
