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Ablation of Diffuse Vocal Cord Papillomatosis Using Digital
AcuBlade™ Scanning Micromanipulator and FiberLase™ Flexible
CO2 Laser Fiber in Patient with Major Retrognathia
Case by Marc Remacle, M.D. | CHU Mont-Godinne, University of Louvain, Belgium
ENT Technique Guide Series Volume 12, No. 4, April 2012 PB-1125160_A
This procedure demanded precision and control. The Digital AcuBlade scanning micromanipulator provided the
highest degree of both for accessible areas. For areas inaccessible to the DAB, the FiberLase flexible CO2 laser fiber still
enabled a high level of precision and control.
Preoperative
Past Medical
History and
Presenting
Complaint
 39 year-old male. Overall state of health was good.
 Persistent dysphonia
 History of laryngeal papillomatosis, HPV 6
 Four prior procedures at another institution
Relevant Physical
Findings and
Diagnostics
 Major retrognathia
 Diffuse papillomatosis involving the 2 vocal folds including the anterior
commissure
Diagnosis  Diffuse papillomatosis involving both vocal folds including anterior commissure
Operative
Surgical
Procedure
 Because of retrognathia, it was very difficult to expose by direct laryngoscopy with
conventional laryngoscopes. Visualization of anterior 1/3 part of vocal folds and of
anterior commissure was impossible through the operative microscope.
 Procedure performed was CO2 Laser-Assisted Microlaryngoscopy using Digital
AcuBlade for posterior and mid-parts of the cords and fiber-delivered CO2 laser
ablation using 30° rigid endoscope visualization for anterior cords and anterior
commisure.
Anesthesia  Procedure performed under general anesthesia because of the extent of the
papillomatosis involving the two cords
Ablation of Diffuse Vocal Cord Papillomatosis
Using Digital AcuBlade™ Scanning Micromanipulator and FiberLase™ Flexible CO2 Laser Fiber
Marc Remacle, M.D.
2
Laser
Accessories
 Digital AcuBlade scanning micromanipulator
 FiberLase flexible CO2 laser fiber with 240mm malleable handpiece
Smoke
Evacuation
 Smoke evacuation was not required because of the purge-air flow
Laser and
Parameters
 Laser System 1: UltraPulse SurgiTouch Surgical CO2 Laser System
 Laser Operation Mode: SurgiTouch Scanning Mode
- Control Panel Settings: ENT, Larynx, Digital AcuBlade 400mm
- Power: default, 16 Watts
- Circle shape, 1-2 mm size, scan depth set to 1
 Exposure Mode and Time: Repeat, 0.1 sec. between scans
 Laser System #2: AcuPulse 40WG with FiberLase Flexible CO2 Laser Fiber
 Laser Operation Mode: SuperPulse, 12 Watts
 Exposure Mode and Time: Repeat Time ON 0.1 sec., Time OFF 0.1 sec.
Laser
Technique
 Procedure Part A: Laser System #1 was used to ablate papillomatosis of posterior
and mid-parts of vocal cords under microscope visualization
 Procedure Part B. Laser System #2 was used to ablate lesions of anterior parts of
vocal cords and of anterior commissure under 30° rigid scope visualization. The
distance from the tip of the fiber to tissue was 1-2 mm.
 The end-point for ablation was when epithelium seemed fully ablated. Char was
removed with saline-soaked cottons to ensure there was no remaining epithelium.
 Cidofovir injection (7.5 mg/ml) to affected areas at conclusion of procedure
Hemostasis  Cautery was available, but was not used.
 Hemostasis was accomplished by the laser or cottonoids soaked with saline
solution and adrenaline.
Technique Tips
Avoid Deep
Ablation
in Reinke’s Space
 The goal of this surgery was superficial ablation of the epithelium. For controlling
the depth of ablation without risk of thermal damage in the Reinke’s space, the
REPEAT DELAY was used between Digital AcuBlade scans.
Minimize Thermal
Damage to
Mucosa
 When using the FiberLase CO2 laser fiber, REPEAT mode was used to maintain
control and minimize thermal trauma to delicate tissues.
Visualization  Use saline-soaked cottonoids to periodically wipe away char and permit good
assessment of treatment planes. Removal of char also helps minimize thermal
build up.
Ablation of Diffuse Vocal Cord Papillomatosis
Using Digital AcuBlade™ Scanning Micromanipulator and FiberLase™ Flexible CO2 Laser Fiber
Marc Remacle, M.D.
3
Operative Photos
Fig. 1 Limited visualization of cords through
conventional laryngoscope ( Remacle model, Wolf©)
Fig. 2 Ablation of posterior parts of vocal cords with
Digital AcuBlade scanning micromanipulator (circle)
Fig. 3 Ablation of anterior parts of vocal cords and
anterior commissure with FiberLase CO2 waveguide
under 30° telescope
Fig. 4 Final view with 30° telescope. Slightly more
carbonization occurred with fiber in comparison with
Acublade, as expected
Fig. 5 Final postoperative view with 70° telescope Fig. 6 Cidofovir injection
Ablation of Diffuse Vocal Cord Papillomatosis
Using Digital AcuBlade™ Scanning Micromanipulator and FiberLase™ Flexible CO2 Laser Fiber
Marc Remacle, M.D.
4
Post Operative
Discharge and
Postoperative
Instructions
 Procedure length was approximately 30 min.
 Patient was discharged the same day
 Aerosol therapy with saline solution & voice rest for 10 days
 Antibiotic therapy for 3 days
 PPI (pantozole) 40 mg, administered orally, two times per day until healing
completed
Recovery
and Outcome
 The patient experienced pain in the throat for 5-6 days
 The patient has been back once for retreatment. His disease was significantly
lessened.
 The voice was well improved
Discussion
In this patient, surgery was impossible to perform through the microscope. Another fiber –delivered laser
wavelength could have been used, but with the CO2 laser hollow fiber, you really see what you are doing
without risk of deep thermal damages – even at the level of the anterior commissure.

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Ablation of Diffuse Vocal Cord Papillomatosis Using Digital AcuBlade™ Scanning Micromanipulator and FiberLase™ Flexible CO2 Laser Fiber in Patient with Major Retrognathia Case by Marc Remacle, M.D. | CHU Mont-Godinne, University of Louvain, Belgium

  • 1. Ablation of Diffuse Vocal Cord Papillomatosis Using Digital AcuBlade™ Scanning Micromanipulator and FiberLase™ Flexible CO2 Laser Fiber in Patient with Major Retrognathia Case by Marc Remacle, M.D. | CHU Mont-Godinne, University of Louvain, Belgium ENT Technique Guide Series Volume 12, No. 4, April 2012 PB-1125160_A This procedure demanded precision and control. The Digital AcuBlade scanning micromanipulator provided the highest degree of both for accessible areas. For areas inaccessible to the DAB, the FiberLase flexible CO2 laser fiber still enabled a high level of precision and control. Preoperative Past Medical History and Presenting Complaint  39 year-old male. Overall state of health was good.  Persistent dysphonia  History of laryngeal papillomatosis, HPV 6  Four prior procedures at another institution Relevant Physical Findings and Diagnostics  Major retrognathia  Diffuse papillomatosis involving the 2 vocal folds including the anterior commissure Diagnosis  Diffuse papillomatosis involving both vocal folds including anterior commissure Operative Surgical Procedure  Because of retrognathia, it was very difficult to expose by direct laryngoscopy with conventional laryngoscopes. Visualization of anterior 1/3 part of vocal folds and of anterior commissure was impossible through the operative microscope.  Procedure performed was CO2 Laser-Assisted Microlaryngoscopy using Digital AcuBlade for posterior and mid-parts of the cords and fiber-delivered CO2 laser ablation using 30° rigid endoscope visualization for anterior cords and anterior commisure. Anesthesia  Procedure performed under general anesthesia because of the extent of the papillomatosis involving the two cords
  • 2. Ablation of Diffuse Vocal Cord Papillomatosis Using Digital AcuBlade™ Scanning Micromanipulator and FiberLase™ Flexible CO2 Laser Fiber Marc Remacle, M.D. 2 Laser Accessories  Digital AcuBlade scanning micromanipulator  FiberLase flexible CO2 laser fiber with 240mm malleable handpiece Smoke Evacuation  Smoke evacuation was not required because of the purge-air flow Laser and Parameters  Laser System 1: UltraPulse SurgiTouch Surgical CO2 Laser System  Laser Operation Mode: SurgiTouch Scanning Mode - Control Panel Settings: ENT, Larynx, Digital AcuBlade 400mm - Power: default, 16 Watts - Circle shape, 1-2 mm size, scan depth set to 1  Exposure Mode and Time: Repeat, 0.1 sec. between scans  Laser System #2: AcuPulse 40WG with FiberLase Flexible CO2 Laser Fiber  Laser Operation Mode: SuperPulse, 12 Watts  Exposure Mode and Time: Repeat Time ON 0.1 sec., Time OFF 0.1 sec. Laser Technique  Procedure Part A: Laser System #1 was used to ablate papillomatosis of posterior and mid-parts of vocal cords under microscope visualization  Procedure Part B. Laser System #2 was used to ablate lesions of anterior parts of vocal cords and of anterior commissure under 30° rigid scope visualization. The distance from the tip of the fiber to tissue was 1-2 mm.  The end-point for ablation was when epithelium seemed fully ablated. Char was removed with saline-soaked cottons to ensure there was no remaining epithelium.  Cidofovir injection (7.5 mg/ml) to affected areas at conclusion of procedure Hemostasis  Cautery was available, but was not used.  Hemostasis was accomplished by the laser or cottonoids soaked with saline solution and adrenaline. Technique Tips Avoid Deep Ablation in Reinke’s Space  The goal of this surgery was superficial ablation of the epithelium. For controlling the depth of ablation without risk of thermal damage in the Reinke’s space, the REPEAT DELAY was used between Digital AcuBlade scans. Minimize Thermal Damage to Mucosa  When using the FiberLase CO2 laser fiber, REPEAT mode was used to maintain control and minimize thermal trauma to delicate tissues. Visualization  Use saline-soaked cottonoids to periodically wipe away char and permit good assessment of treatment planes. Removal of char also helps minimize thermal build up.
  • 3. Ablation of Diffuse Vocal Cord Papillomatosis Using Digital AcuBlade™ Scanning Micromanipulator and FiberLase™ Flexible CO2 Laser Fiber Marc Remacle, M.D. 3 Operative Photos Fig. 1 Limited visualization of cords through conventional laryngoscope ( Remacle model, Wolf©) Fig. 2 Ablation of posterior parts of vocal cords with Digital AcuBlade scanning micromanipulator (circle) Fig. 3 Ablation of anterior parts of vocal cords and anterior commissure with FiberLase CO2 waveguide under 30° telescope Fig. 4 Final view with 30° telescope. Slightly more carbonization occurred with fiber in comparison with Acublade, as expected Fig. 5 Final postoperative view with 70° telescope Fig. 6 Cidofovir injection
  • 4. Ablation of Diffuse Vocal Cord Papillomatosis Using Digital AcuBlade™ Scanning Micromanipulator and FiberLase™ Flexible CO2 Laser Fiber Marc Remacle, M.D. 4 Post Operative Discharge and Postoperative Instructions  Procedure length was approximately 30 min.  Patient was discharged the same day  Aerosol therapy with saline solution & voice rest for 10 days  Antibiotic therapy for 3 days  PPI (pantozole) 40 mg, administered orally, two times per day until healing completed Recovery and Outcome  The patient experienced pain in the throat for 5-6 days  The patient has been back once for retreatment. His disease was significantly lessened.  The voice was well improved Discussion In this patient, surgery was impossible to perform through the microscope. Another fiber –delivered laser wavelength could have been used, but with the CO2 laser hollow fiber, you really see what you are doing without risk of deep thermal damages – even at the level of the anterior commissure.