2. Wound Healing
Wound repair requires an
environment which is conducive to
epithelialization, collagen
formation, angiogenesis, and
wound contracture
Cleveland VA Medical Center
20. Treatment Principles
Prevention
ā¢ Good glycemic control
ā¢ Daily foot inspections
ā¢ "Diabetic" socks
ā¢ Change shoes in middle of day
ā¢ Weight distributing insoles q6months
ā¢ Regular professional care
Neuropathic Ulcers
Cleveland VA Medical Center
22. Treatment Principles
Methods of Reducing Pressure
ā¢Total Contact Cast
ā¢Felted foam dressings
ā¢Firm but moldable insoles
ā¢Rocker bottom soles
ā¢Metatarsal bars
ā¢Non-weight bearing
Neuropathic Ulcers
Cleveland VA Medical Center
24. Treatment Principles
Diagnose and Control Infection
ā¢ signs and symptoms
ā¢ radiographs
ā¢ wound cultures and sensitivities
ā¢ antibiosis
Treatment of Dermal Wounds
Cleveland VA Medical Center
26. Treatment Principles
Diagnose and Control Infection
Signs and Symptoms
ā¢ Fever
ā¢ Cellulitis - Lymphangitis
ā¢ Drainage
ā¢ Foul odor
ā¢ Palpable - tender lymph nodes
Treatment of Dermal Wounds
Cleveland VA Medical Center
27. Treatment Principles
Diagnose and Control Infection
Radiographs
ā¢ baseline
ā¢ soft tissue swelling & density
ā¢ soft tissue planes
ā¢ gas
ā¢ bone involvement
Treatment of Dermal Wounds
Cleveland VA Medical Center
28. Treatment Principles
Diagnose and Control Infection
Wound cultures and Sensitivities
ā¢ Curette base of wound
ā¢ aerobic and anaerobic if indicated
ā¢ If wound probes to bone ā it is infected until proven otherwise
Treatment of Dermal Wounds
Cleveland VA Medical Center
29. Treatment Principles
Diagnose and Control Infection
Antibiosis
ā¢ begin broad spectrum coverage
ā¢ Cover MRSA if recent antibiotics or hx of MRSA
ā¢ reassess after culture is returned
Treatment of Dermal Wounds
Cleveland VA Medical Center
31. Treatment Principles
Debridement
ā¢ sharp debridement if applicable
ā¢ wet to dry dressings
ā¢ saline preferred
ā¢ Dakin's-Betadine-Peroxide-Acetic acid ?
ā¢ enzymatic debridement if ischemic
ā¢ autolysis
Treatment of Dermal Wounds
Cleveland VA Medical Center
32. Treatment Principles
AUTOLYSIS
the body's wound fluid hydrates and lyses
the wound by mobilizing the body's own
enzymes
Treatment of Dermal Wounds
Cleveland VA Medical Center
33. Treatment Principles
Wound Dressings
A moist wound environment is
physiologic and speeds
epithelialization
Treatment of Dermal Wounds
Cleveland VA Medical Center
34. Treatment Principles
Wound Dressings
ā¢ Epithelialization occurs up to
50% faster in a moist
environment than in a dry
environment.
ā¢ Wound fluid possesses growth factors
that stimulate angiogenesis and
epithelialization
Treatment of Dermal Wounds
Cleveland VA Medical Center
35. Treatment Principles
Wound Dressings
There is no evidence that anything
stimulates granulation tissue with
the possible exception of growth
factors
Treatment of Dermal Wounds
Cleveland VA Medical Center
36. Treatment Principles
Phases of Healing
Cleveland VA Medical Center
I. Inflammatory Phase
Erythema, warmth, edema, pain
A) Vasoconstriction
B) Vasodilation
C) Leukocyte migration
D) Monocytes > macrophages
37. Treatment Principles
Phases of Healing
Cleveland VA Medical Center
II. Proliferative Phase
ā¢ Beefy red granulation tissue
Macrophages
Collagen synthesis
Angiogenesis
ā¢ Thin, silvery epithelial layer
Epithelialization
ā¢ Wound shrinkage
Contraction
38. Treatment Principles
Phases of Healing
Cleveland VA Medical Center
III. Maturation Phase
Shrinkage, thinning, paling of scar
Collagen remodeling
Capillary regression
Tensile strength increases
39. Treatment Principles
Ask yourself the following questions
Is it arterial?
Is it venous?
Is it neuropathic?
Is it infected?
Is there osteomyelitis?
SUMMARY
Cleveland VA Medical Center