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You expose three unknown bacterial strains plus a wildtype strain to DNA damaging agents.
You observe the following survival percentages. UV causes thymidine dimers. H 2 O 2 causes
guanine oxidation to 8-oxo-deoxyguanine (a BER substrate), sodium nitrite (NaNO2) causes
deamination of cytosine to uracil. Which DNA repair pathways are mutated in strains A , B , and
C ?

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  • 1. You expose three unknown bacterial strains plus a wildtype strain to DNA damaging agents. You observe the following survival percentages. UV causes thymidine dimers. H 2 O 2 causes guanine oxidation to 8-oxo-deoxyguanine (a BER substrate), sodium nitrite (NaNO2) causes deamination of cytosine to uracil. Which DNA repair pathways are mutated in strains A , B , and C ?