Cephalosporins are a class of antibiotics derived from the fungus Cephalosporium acremonium. The first cephalosporin discovered was cephalosporin C. All other cephalosporins are semi-synthetic derivatives of cephalosporin C. Cephalosporins contain a beta-lactam ring like penicillins but also contain a dihydrothiazine ring, unlike penicillins. They are classified into generations based on when they were synthesized, with later generations having broader spectra of activity against both gram-positive and gram-negative bacteria.