Medicine PG poster presentation

1. CHARCOT’S – INTERESTING FACTS
1. CHARCOT-MARIE-TOOTH DISEASE (CMT)
ALSO KNOWN AS HEREDITARY MOTOR AND SENSORY NEUROPATHY (HMSN) OR PERONEAL
MUSCULAR ATROPHY.
• HETEROGENEOUS INHERITED DISORDER OF NERVES (NEUROPATHY) THAT IS CHARACTERIZED BY
LOSS OF MUSCLE TISSUE AND TOUCH SENSATION, PREDOMINANTLY IN THE FEET AND LEGS BUT
ALSO IN THE HANDS AND ARM
2. CHARCOT’S JOINT/FOOT (NEUROPATHIC OSTEOARTHROPATHY)
• REFERS TO PROGRESSIVE DEGENERATION OF A WEIGHT BEARING JOINT, A PROCESS MARKED BY BONY
DESTRUCTION, BONE RESORPTION, AND EVENTUAL DEFORMITY.
• IF THIS PATHOLOGICAL PROCESS CONTINUES UNCHECKED, IT COULD RESULT IN JOINT
DEFORMITY, ULCERATION AND SUPERINFECTION,
3. CHARCOT'S NEUROLOGIC TRIAD
• NYSTAGMUS
• INTENTION TREMOR
• SCANNING OR STACCATO SPEECH.
• THIS TRIAD IS ASSOCIATED WITH MULTIPLE SCLEROSIS, WHERE IT WAS FIRST DESCRIBED
4. CHARCOT'S CHOLANGITIS TRIAD
• JAUNDICE
• FEVER USUALLY WITH RIGORS
• RIGHT UPPER QUADRANT ABDOMINAL PAIN.
WHEN THE PRESENTATION ALSO INCLUDES HYPOTENSION AND MENTAL STATUS CHANGES, IT IS KNOWN AS
REYNOLDS' PENTAD
5. CHARCOT-BOUCHARD ANEURYSMS ( MILIARY ANEURYSMS OR MICROANEURYSMS)
• ANEURYSMS OF THE BRAIN VASCULATURE WHICH OCCUR IN SMALL BLOOD VESSELS (LESS THAN 300 MICROMETRE
DIAMETER). . CHARCOT-BOUCHARD ANEURYSMS ARE MOST OFTEN LOCATED IN THE BRAINSTEM.
• ASSOCIATED WITH CHRONIC HYPERTENSION
6. CHARCOT-LEYDEN CRYSTALS
• MICROSCOPIC CRYSTALS
•
• ALLERGIC DISEASES SUCH AS ASTHMA OR PARASITIC INFECTIONS