2. STEM CELLS
STEM CELLS ARE THEMASTER CELLS.
THE REW MATERIAL –FROM WHICH ALL OF
THE BODY CELLS MATURE .
THEY GIVE RISE TO BRAIN CELLS,PANCREATIC
CELLS,HEART CELLS ETC.
PROPERTIES............
UNDIFFERENTIATE OR UNSPECIALIZED CELLS.
HAVING SELF RENEWAL PROPERTY.
3. TYPES OF STEM CELLS..............
EMBRYONIC –DERIVED FROM THE INNER CELL
MASS OF A BLATOCYST.
ADULT -DERIVED FROM MATURE ORGANISM
LIKE IN CORNEA,KIDNEY,ETC
FETAL - DRIVED FROM ABORTED FETAL TISSUE.
UMBLICAL - DRIVED FROM UMBLICAL CORDS.
4. STEM CELL
THERAPY...............
STEM CELL THERAPY IS THE INTRODUCTION OF
NEW ADULT STEM CELL INTO DAMAGED TISSUE
IN ORDER TO TREAT DISEASE OR INJUIRY.
THEY ARE USED TO CURE MANY DISEASE SUCH
AS;
ALZHEIMER’S DISEASE,HEART -DISEASE,ETC........
10. Human iPSC technology potentially can be used for
screening new cancer drugs and ultimately for providing
cells for transplant to treat a variety of diseases, including
cancer (yellow box). Genetic mutations can be corrected in
patient-derived iPSCs by gene targeting approaches. The
main hurdles to using patient-specific iPSCs for disease
modeling, drug screening, and transplantation purposes
are (i) a lack of effective differentiation protocols, (ii) little
or no engraftment capability for the majority of human
iPSC-derived specialized cells, (iii) difficulties in modeling
multifactorial diseases, (iv) the need for GMP-compliant
conditions at each step, and (v) safety concerns regarding
the potential tumorigenicity of iPSCs associated with their
pluripotent state or with insertional- or culture-driven
mutagenesis.