2014 education course cell therapy in ocular disease-description-and-agenda-2.18.2014 (2)
1. Orange County Convention Center
Orlando, Florida
May 3, 2014, 8:30am – 4:30pm
Cell Therapy in Ocular Disease — Emerging Research and Therapy
Organizers: David D. Eveleth, PhD; Julie T. Daniels, PhD
Course Description
Cell therapy in the eye is emerging from the research arena into clinical care. Cell therapies are in clinical development
for both corneal and retinal conditions, and the development of cell therapies is an active field of research in
ophthalmology. This course reviews the current approaches to cell therapy in the eye, including both cornea and retina.
The focus is on translation of basic research to human therapies, with sessions on emerging research areas, cell therapy
approaches expected to reach the clinic soon and several cell therapies currently undergoing clinical trials. Participants
will gain an understanding of: the current state of clinical/translational therapies, challenges, and solutions for
translation of research into the clinic, and unmet needs in cell therapy.
Agenda*
Time Frame Topic Speaker(s)
8:30 – 8:45am Introduction David Eveleth, PhD
8:45a – 9:15am The ocular surface: an exemplar for cell
therapy development and delivery
Julie T. Daniels, PhD
9:15 – 9:45am Therapy for corneal scars using autologous
stem cells
James L. Funderburgh, PhD FARVO
9:45 – 10:15am Regulatory approval of corneal endothelial
cell based therapy
Jodhbir S. Mehta, FRCS Ed MD
10:15 – 10:30am Panel Discussion Julie T. Daniels, PhD (moderator)
10:30 – 10:45am Break
10:45 – 11:15am Cone photoreceptor rescue with stem cell
transplantation
Henry J. Kaplan, MD FARVO
11:15 – 11:45am Retinal progenitor cells for treatment of
retinitis pigmentosa
Henry J. Klassen, MD PhD
11:45am – 12:45pm Lunch
12:45 - 1:15pm Transplantation of ES derived RPE: update
on clinical studies
Steven D. Schwartz, MD FARVO
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2. 1:15 – 1:45pm The adult human RPE stem cell, a source
for disease modeling and transplantation
for Age-Related Macular Degeneration
Timothy A. Blenkinsop, BS MSc PhD
1:45 – 2:15pm Muller glia and therapeutic
regeneration:Promises and limitations
Iqbal Ahmad, PhD
2:15 – 2:30pm Panel Discussion Henry J. Kaplan, MD FARVO (moderator)
2:45 – 3:00pm Break
3:00 – 3:30pm Mechanisms for ocular cell-based products Paul K. Williamson, MD
3:30 – 4:00pm Long term delivery of biologics for retinal
disease by ECT (Encapsulated Cell
Technology)
Arturo Santos, MD
4:00 – 4:30pm Panel Discussion David Eveleth, PhD (moderator)
4:30pm Course ends
*The agenda and speakers are subject to change.
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