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What is cancer?
• Uncontrolled growth of abnormal cells in the
  body
• Normal cells multiply when the body requires
  them, and die when no longer needed.
  – Regulated controls within genome
     • Activating Oncogenes accelerating cell growth &
       division
     • Inactivating tumor suppressor genes
Causes?
•   Chemicals
•   Environmental toxins
•   Ionizing radiation
•   Genetics
•   Pathogens
Incidence in India

• In most populations, childhood cancer
  ranges from 75 – 150 per million children
  per year

• Standardized incidence rate for India: 38
  – 124 per million children per year
• India’s current population: 1,155,347,700
  – Severe underreporting
• Worldwide, 70 – 90% of children are cured of
  cancer

• In India, over 70% of children still die
  – Lack of awareness
  – Inadequate treatment
CanKids
• Facilitate a 70-90% survival rate for children
  with cancer in India

• Branch of the Indian Cancer Society

• Founded in 2004 by Poonam Bagai – 2001
  colon cancer survivor
  – Assisted 2500 children in medical treatment
Mission
• Best possible treatment
• Social economic support
  – Adopt a child program
  – Home away from home
• Reintegration into society
  – Education
• Psychological support
• Continuity of care
Retinoblastoma
What is it?




Retinoblastoma is cancer of the light
     sensitive cells of the retina
          image source: http://www.wightoptometrists.co.nz/?sid=42
Incidence of
  Retinoblastoma


•   Rare
•   Genetic in some cases
•   Affects children <5 years old
•   Worldwide – 98% treated
•   India – 60 % cured (AIIMS)
    – 1500-2000 patients per year
Symptoms
• Crossed eye
• Poor vision
• Red, swelling eye
• Enlarged pupil
• Different colored
  irises
• Pain
Leukocoria
  White Eye Reflex




» Affordable and simple method of diagnosis
Treatment




• Chemotherapy
• Radiotherapy
• Enucleation
CanKids RB Project
• Public Awareness
  – Reduce need for radical ophthalmic surgery
  – Early detection
  – Educate the public
     • Retinoblastoma is curable
     • Female/Male Incidence
  – International RB
    Awareness Day
Cankids RB Project

• Advocacy
  – Empower medical teams
  – Deliver higher quality evidence based care


• Patient Support
  – Sajeev CanKids RB Fund
  – Financial aid

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CanKids Volunteering

  • 1.
  • 2. What is cancer? • Uncontrolled growth of abnormal cells in the body • Normal cells multiply when the body requires them, and die when no longer needed. – Regulated controls within genome • Activating Oncogenes accelerating cell growth & division • Inactivating tumor suppressor genes
  • 3. Causes? • Chemicals • Environmental toxins • Ionizing radiation • Genetics • Pathogens
  • 4. Incidence in India • In most populations, childhood cancer ranges from 75 – 150 per million children per year • Standardized incidence rate for India: 38 – 124 per million children per year • India’s current population: 1,155,347,700 – Severe underreporting
  • 5. • Worldwide, 70 – 90% of children are cured of cancer • In India, over 70% of children still die – Lack of awareness – Inadequate treatment
  • 6. CanKids • Facilitate a 70-90% survival rate for children with cancer in India • Branch of the Indian Cancer Society • Founded in 2004 by Poonam Bagai – 2001 colon cancer survivor – Assisted 2500 children in medical treatment
  • 7. Mission • Best possible treatment • Social economic support – Adopt a child program – Home away from home • Reintegration into society – Education • Psychological support • Continuity of care
  • 9. What is it? Retinoblastoma is cancer of the light sensitive cells of the retina image source: http://www.wightoptometrists.co.nz/?sid=42
  • 10. Incidence of Retinoblastoma • Rare • Genetic in some cases • Affects children <5 years old • Worldwide – 98% treated • India – 60 % cured (AIIMS) – 1500-2000 patients per year
  • 11. Symptoms • Crossed eye • Poor vision • Red, swelling eye • Enlarged pupil • Different colored irises • Pain
  • 12. Leukocoria White Eye Reflex » Affordable and simple method of diagnosis
  • 14. CanKids RB Project • Public Awareness – Reduce need for radical ophthalmic surgery – Early detection – Educate the public • Retinoblastoma is curable • Female/Male Incidence – International RB Awareness Day
  • 15. Cankids RB Project • Advocacy – Empower medical teams – Deliver higher quality evidence based care • Patient Support – Sajeev CanKids RB Fund – Financial aid