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Mental Health Policy II
Definitions, Epidemiology, Service Use and
Access
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
The D.S.M. would do well to recognize that a broken heart is not a medical
condition, and that medication is ill-suited to repair some tears. Time does not
heal all wounds, closure is a fiction, and so too is the notion that God never
asks of us more than we can bear. Enduring the unbearable is sometimes
exactly what life asks of us.
But there is a sweetness even to the intensity of this pain I feel. It is the thing
that holds me still to my son. And yes, there is a balm even in the pain. I shall
let it go when it is time, without reference to the D.S.M., and without the aid of
a pill.
- Ted Gup fellow of the Edmond J. Safra Center for Ethics at Harvard
University writing on the loss of his son to a drug overdose and the
pathologizing of grief in the DSM 5. (NY Times, April 2013)
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 Nature versus nurture controversy…. Is mental illness
inherited, caused by stressful environmental conditions,
or an interaction of both?
 What are the implications for a person who is diagnosed
as having a “mental disease”? (A “schizophrenic”)
 How important are cultural determinants and social
determinants (poverty, racism, sexism)?
 Is the term “mental illness” even logical?
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Definitions, Epidemiology, Service Use and Access
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1. Strictly speaking, disease or illness can affect only the body; hence, there can be no
mental illness.
2. “Mental illness” is a metaphor. Minds can be “sick” only in the sense that jokes are
“sick” or economies are “sick.”
3. Psychiatric diagnoses are stigmatizing labels, phrased to resemble medical
diagnoses and applied to persons whose behavior annoys or offends others.
4. Those who suffer from and complain of their own behavior are usually classified as
“neurotic”; those whose behavior makes others suffer, and about whom others
complain, are usually classified as “psychotic.”
5. 5. Mental illness is not something a person has, but is something he does or is.
Szasz, Thomas S. (2011-07-12). The Myth of Mental Illness: Foundations of a Theory of Personal
Conduct (p. 267). HarperCollins. Kindle Edition.
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Definitions, Epidemiology, Service Use and Access
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
Should we adopt a broad definition of disease that includes all the
following possibilities to understand the cause(s) of mental illness?
Disease: any condition that impairs normal functioning.
Types:
1) Pathogenic (common cold)
2) Deficiency (anemia)
3) Hereditary (Down’s Syndrome)
4) Physiological--malfunction of body organ (“chemical imbalance”)
asthma-lungs
diabetes-pancreas
addiction, schizophrenia, bipolar disorder-brain
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
Fundamental changes in brain help
“explain” continued drug use and relapse.
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
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…the fact that addiction is associated with neurobiological changes is not, in itself, proof
that the addict is unable to choose.
Robert Downey Jr. was once a poster boy for drug excess. “It’s like I have a loaded gun
in my mouth and my finger’s on the trigger, and I like the taste of gunmetal,” he said. It
seemed only a matter of time before he would meet a horrible end. But Downey entered
rehab and decided to change his life. Why did Downey use drugs? Why did he decide to
stop and to remain clean and sober?
An examination of his brain, no matter how sophisticated the probe, could not tell us why
and perhaps never will.
The key problem with neurocentrism is that it devalues the importance of
psychological explanations and environmental factors, such as familial chaos,
stress, and widespread access to drugs, in sustaining addiction.
Satel, Sally; Lilienfeld, Scott O. (2013-05-16). Brainwashed: The Seductive Appeal of
Mindless Neuroscience . Basic Books. Kindle Edition.
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 Evidence does suggest an inherited component for
some disorders:
 Schizophrenia spectrum and other psychotic
disorders
 Bipolar disorder
 Major depressive disorder
 Borderline personality disorder
 ASP
 Alcoholism (stronger genetic link for men)
 But none are 100% heritable and the genetic component
is less clear for other disorders such as the phobias.
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Definitions, Epidemiology, Service Use and Access
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 Other models of mental illness (all have modest support
but none can explain all mental illnesses):
 Psychosocial development (psychoanalytic
psychology; “schizophrenegenic mother”)
 Learning theory (at first, purely behavioral and then
cognitive behavioral implications)
 Social-stress (stressful conditions cause
psychological breakdowns particularly in pre-
disposed individuals – interaction idea)
 Labeling theory – (deviant behaviors labeled as
illness, mental illness as a social construct – Szasz)
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Definitions, Epidemiology, Service Use and Access
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
Alas, we have reviewed dozens of definitions of mental disorder (and helped to
write the one in DSM-IV) and must admit that none have much practical value
(Wakefield 1992, Wakefield & First 2003).
Historically, conditions have become mental disorders by accretion and practical
necessity, not because they met some independent set of abstract and
operationalized definitional criteria. Indeed, the concept of mental disorder is so
amorphous, protean, and heterogeneous that it inherently defies definition—
creating a hole at the center of psychiatric classification.
The common themes in the definition of mental disorder are distress, disability,
dyscontrol, and dysfunction but these are very imprecise and nonspecific
markers with little practical value.
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
As one illustration, it has become crystal clear that there is no one prototype
“schizophrenia” waiting to be explained with one incisive and sweeping
biological model. Instead, a painful process of promising false starts has taught
us there is no single gene, or small subset of genes, to account for
schizophrenia.
… schizophrenia is rather a group of disorders, or perhaps better, a mob. There
may eventually turn out to be 20 or 50 or 200 kinds of schizophrenia, and its
definitions are necessarily arbitrary constructs. There is no clear right way to
diagnose this gang or even much agreement on what the validators should be
and how they should be applied.
(Frances and Widiger paper, no longer assigned)
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
Pragmatic concerns must play so central a role because the DSM is an official
system of classification that has a huge (perhaps excessive) influence on how
everything works in the mental health world: who gets diagnosed, how they are
treated, who pays for it, whether disability is appropriate, and whether someone
can be involuntarily committed, released from legal responsibility, or sue for
damages.
Fads in diagnosis come and go and have been with us as long as there has
been psychiatry. The fads meet a deeply felt need to explain, or at least to label,
what would otherwise be unexplainable human suffering and deviance. In
recent years the pace has picked up, with false epidemics coming in bunches
that involve an ever-increasing proportion of the population. We are now in the
midst of at least four such epidemics: autism, attention deficit, childhood bipolar
disorder, and paraphilia not otherwise specified.
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History of the DSM
• 1952 – First edition
• 1968 – Second Edition DSM-II – only 136 pages
• 1980 – DSM-III published after work had begun in 1974
• 1987 – Publication of DSM-III-R after APA appointed a work group to
revise and correct DSM-III
• 1994 – Publication of DSM-IV
• 2000 – Publication of DSM-IV-Text Revision
• 2013 – Publication of DSM-5
See Blashfield, Keeley et al. (2014) on syllabus.
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Mental Health Policy II
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 Prevalences studies of national scope were not done prior to the
1980s.
 Psychiatry was dominated by psychoanalytic/psychodynamic
thinking as embodied in DSM-1 and DSM-2, which focused on
etiological understanding and not symptoms or classifications.
 Administering a structured survey to thousands of people using lay
interviewers was not possible with DSM-2 because the specific
criteria for a given disorder were not available in DSM-2.
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Mental Health Policy II
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• DSM-III was a radical departure from DSM-2
• Removed focus from etiology to symptoms and classification
and increased number of diagnoses.
• Coordinated with development of ICD-9.
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
 DSM-5 continues the trend. It is 947 pages long and has over 500
diagnostic conditions.
 Use of the DSM-5 could result in higher estimated rates of mental
illness as it requires fewer symptoms for shorter durations to meet
diagnostic thresholds.
 The abandonment of the Roman numeral (e.g., III, IV) was
intentional with the goal being more frequent revisions as scientific
findings emerge. The revisions will be labeled 5.1, 5.2. etc.
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Mental Health Policy II
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 Per Mayes and Horwitz, and Blashfield et al.:
 The basic transformation in the DSM-III was its development and use of
a model that equated visible and measurable symptoms with the
presence of diseases.
 This symptom-based model allowed psychiatry to develop a
standardized system of measurement.
 Such a standardized system benefited numerous interests. It allowed
research-oriented psychiatrists (“neo-Kraepelinians”), a small but highly
influential group in the profession, to measure mental illness in reliable
and reproducible ways.
 It also helped silence the critics of the previous system, who claimed
that mental illnesses could not be defined in any objective way (e.g.,
Szaz – but he maintained his criticism).
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
 Per Mayes and Horwitz:
 For clinicians, the new diagnostic system legitimized claims to be
treating real diseases and, most importantly, allowed them to obtain
reimbursement from third party insurers.
 Because the manual defined illnesses solely through symptoms without
regard to causes, it was theory-neutral and could be used by clinicians
of all theoretical persuasions.
 The symptom-based manual also met the needs of pharmaceutical
companies to have specific diseases for their products to treat.
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
 DSM-III came about, in part, as a result of many pressures on the
psychiatric profession:
 Psychiatry’s marginal status within the medical profession
 Increasing reluctance of insurance companies and the government to
reimburse long-term talk therapy
 The need to treat formerly institutionalized seriously mentally ill
persons in the community, the growing influence of medication
treatments
 Growing professional threat from non-physicians such as clinical
psychologists, counselors, and social workers.
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
 The confluence of these pressures led to a new DSM that fundamentally
redefined what mental disorders were and how they should be identified,
diagnosed, and treated.
 “By intent and careful plan the developers of DSM-III sought to bring about
a revolution in how mental health professionals thought about and practiced
psychiatric diagnosis. On many levels, the revolution succeeded remarkably
well” (Kirk & Kutchins, 1992, p. 11).
 American psychiatry in the late twentieth century moved from a state of
“brainlessness” to one of “mindlessness.”
 What is of particular interest to social scientists is the extent to which
politics and the underlying economics of psychiatric practice permeated the
DSM-III’s creation.
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
In short, a powerful quartet of voices came together during the 1980’s
eager to inform the public that mental disorders were brain diseases.
• Pharmaceutical companies provided the financial muscle (69% of the DSM-
5 study group contributors had/have direct ties to the pharmaceutical
industry).
• The APA and psychiatrists at top medical schools conferred intellectual
legitimacy upon the enterprise.
• The NIMH [National Institute of Mental Health] put the government’s stamp
of approval on the story.
• NAMI provided moral authority.
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
 With the medicalization of psychiatry came an increased emphasis on
pharmacology rather than talk therapy.
 DSM-III standardized the diagnostic classification scheme for mental
illnesses and disorders but did not include treatment guidelines.
 By virtue of its Kraepelinian orientation, however, it allowed pharmaceutical
companies to market their products for a growing number of specific,
symptom-based disease entities (Healy, 1997).
 The DSM-III unintentionally positioned psychopharmacology on a growth
trajectory that various institutions—insurance companies, managed care
organizations, pharmaceutical companies, and the government—propelled
significantly in subsequent years as they responded to the DSM-III’s new
diagnostic guidelines and research incentives.
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
 The DSM-III allowed for research on the prevalence of disorders because it
provided specific criteria for assessing a disorder.
 The criteria could be coded into questions on a survey form that could be
administered by trained non-professionals (lay interviewers).
 The first survey form was the Diagnostic Interview Schedule (DIS) used in the
ECA study.
 Currently, the Composite International Diagnostic Interview (CIDI) is the
instrument in current use in the WHO and NCS-R studies… NESARC uses
another instrument (AUDADIS).
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
The assumptions underlying the symptom-oriented focus of the DSM-III (and
every version of the DSM since that time) has had some problematic
implications:
 Although the main purpose of the introduction of a separate axis for
personality disorders (Axis II) in DSM–III was to stimulate research on
personality disorders, many researchers subsequently made the implicit
assumption that Axis I and Axis II are independent. Moreover, Axis II
disorders were considered less important or severe. This issue no longer
applies to the DSM-5 since the axial system has been abandoned.
 Much research on DSM has been inspired by another implicit assumption
that each disorder has its own relatively unique etiology and that one
therefore also can and should develop a relatively specific treatment for
each disorder. This assumption has led to recent conflicts between the APA
and NIMH, which has developed its own independent set of criteria.
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
 Most treatment studies and treatment guidelines have focused on the efficacy
and effectiveness of disorder– specific treatments, and not on the effect of a
particular treatment for different disorders or particular aspects of treatment
processes.
 Studies on gene–environment correlations strongly suggest that individuals
vulnerable to depression in part create their own (stressful) environments and
there is high comorbidity between depression and Axis II disorders, particularly
dependent, borderline, and obsessive-compulsive personality disorder, making it
highly unlikely that depression and personality disorders are independent
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Mental Health Policy II
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 Multi-comorbidity is an issue generally with our current diagnostic systems.
 Research has consistently shown that comorbidity between depression, anxiety
and other Axis I disorders is the rule rather than the exception, arguing against
the assumption that depression and other disorders are relatively distinct.
 Epidemiologic and clinical studies have shown extremely high rates of
comorbidities among the disorders, undermining the hypothesis that the
syndromes represent distinct etiologies. (Dohrenwend’s g?)
 Widespread use of “NOS” because the original diagnostic criteria for each
diagnosis were too narrow (to improve reliability). They do not reflect the messy
clinical reality. NOS has been eliminated in DSM-5 and replaced with “other
specified” and “unspecified”.
 Patients with symptoms that straddled diagnoses such as “schizoaffective
disorder”.
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
• The converse of the multi-comorbidity issue is that people with the same
diagnosis can be very heterogeneous because of the mix and match set of
symptoms necessary for diagnosis:
Like essentially all heterogeneous, polygenic illnesses, psychiatric disorders are
poorly captured as categories (which assume significant discontinuities between
‘well’ and ‘ill’ conditions and between any two disorders). DSM categories have
the bizarre property of being both too broad (in the sense that they identify
remarkably heterogeneous populations) and too narrow (in the sense that, given
the large number of arbitrary DSM diagnostic silos, many if not most patients
with a single DSM diagnosis actually qualify for two or more.)
(Casey, B. et al., (2013). DSM-5 and RDoC: progress in psychiatry research?
Neuroscience, 14, 810-814)
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Mental Health Policy II
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 It became necessary in the 1970s to facilitate diagnostic agreement among
clinicians, scientists and regulatory authorities given the need to match patients
with newly emerging pharmacologic treatments…
 While it is true that no system based entirely on clinical description can match
the levels of diagnostic agreement made possible by objective medical tests,
there were no good alternatives for psychiatry when DSM-III was published in
the 1980s. Indeed, even today objective tests and biomarkers for mental
disorders remain research goals rather than clinical tools.
 The DSM-III-R and DSM-IV revisions remained close to the DSM-III approach,
in part because of the dearth of new scientific information. As a result, diagnosis
in the DSM-III, DSM-III-R, and DSM-IV are best understood as useful
placeholders, based on careful description, but not on deeper understandings.
 The use of symptom-based clusters as indicating diagnosis remains a
characteristic of the just-published DSM-5.
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
The goal of this new manual, as with all previous editions, is to provide a common
language for describing psychopathology. While DSM has been described as a
“Bible” for the field, it is, at best, a dictionary, creating a set of labels and defining
each. The strength of each of the editions of DSM has been “reliability” – each
edition has ensured that clinicians use the same terms in the same ways. The
weakness is its lack of validity. Unlike our definitions of ischemic heart disease,
lymphoma, or AIDS, the DSM diagnoses are based on a consensus about clusters
of clinical symptoms, not any objective laboratory measure. In the rest of medicine,
this would be equivalent to creating diagnostic systems based on the nature of
chest pain or the quality of fever. Indeed, symptom-based diagnosis, once common
in other areas of medicine, has been largely replaced in the past half century as we
have understood that symptoms alone rarely indicate the best choice of treatment.
Patients with mental disorders deserve better.
Thomas Insel – NIMH Director (April 2013)
http://www.nimh.nih.gov/about/director/2013/transforming-diagnosis.shtml
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
Insel walked this back within a week or so and issued a joint statement President of APA:
“The DSM-5 represents the best information currently available for clinical diagnosis of
mental disorders. Patients, families, and insurers can be confident that effective
treatments are available and that the DSM is the key resource for delivering the best
available care. The National Institute of Mental Health (NIMH) has not changed its
position on DSM-5.”
Nevertheless, NIMH has come out with its own set of criteria called the Research Domain
Criteria (RDoC). These criteria do not assume a diagnosis first but instead start with how
functioning is impaired in given domains:
“Rather than starting with an illness definition and seeking its neurobiological
underpinnings, RDoC begins with current understandings of behavior-brain relationships
and links them to clinical phenomena.”
http://www.nimh.nih.gov/research-priorities/rdoc/nimh-research-domain-criteria-
rdoc.shtml#toc_matrix
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
 Major prevalence studies over the last 3 decades:
 Epidemiological Catchment Area Study (1980s)
 National Comorbidity Survey (1990s)
 National Comorbidity Survey - Replication (2000s)
 National Epidemiological Survey on Alcohol and Related Conditions
(NESARC) (2000s) – oversamples minorities; includes modules to
assess personality disorders; will be administered longitudinally to
track progression
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Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
Major prevalence studies over the last 3 decades:
 National Survey on Drug Use and Health (annual; focuses on
substance use but also asks a limited number of questions about
mental health symptoms and treatment access).
 Two additional minority-specific psychiatric epidemiology studies
are linked to the NCS-R: the National Survey of African Americans
(NSAA) and the National Latino and Asian American Study
(NLAAS).
 WHO – World Mental Health Surveys (includes NCS-R in the US) in
31 countries.
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 Prevalence rates across studies vary with the ECA study generally
having the lowest rates
 All studies have yielded surprisingly high prevalence rates …..more
people have at least one lifetime DSM disorder than anyone
expected
 Per the NCS-R, the chance of having at least one DSM disorder in
your lifetime is close to 50%
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ECA NCS NCS-R
Affective Disorder 7.1% 11.1% 9.6%
Anxiety Disorder 13.1 18.7 18.2
Substance Use* 6.4 11.3 3.8
Any Disorder 19.5 23.4 26.2
*ECA estimate is for 6 month prevalence
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Rates across the 3 surveys vary but are difficult to compare because:
 Different diagnostic systems
 DSM-III (ECA)
 DSM-IIIR (NCS)
 DSM-IV (NCS-R)
 Different sampling strategies
 ECA was not a national sample (5 sites)
 NCS and NCS-R were national samples
 Change in instrumentation and protocol
 Better use of stem questions
 Computer assisted interviewing (reduces error)
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Other important findings from the NCS-R survey:
 The three most prevalent 12-month disorders found by the NCS-R were
specific phobia (9%), social phobia (7%), and major depressive disorder
(7%).
 The most prevalent 12-month disease classes are anxiety disorders (18%),
mood disorders (10%), impulse-control disorders (9%), and substance use
disorders (4%).
 The most prevalent lifetime disorders are anxiety disorders (29%), mood
disorders (21%), impulse-control disorders (25%), and substance use
disorders (15%).
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Other important findings from the NCS-R survey:
 The mental disorders with the highest proportion of seriously disabling 12-
month cases are: bipolar disorder (83%); drug dependence (57%); and
obsessive-compulsive disorder (51%).
 Impulse-control disorders, which have been neglected in most previous
epidemiological studies of adults, have a greater proportion at the serious
level than either anxiety disorders or substance use disorders.
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Other important findings from the NCS-R survey:
 Severity was strongly related to comorbidity; 9.6% of respondents with 1
diagnosis, 25.5% with 2 diagnoses, and 49.9% with 3 or more diagnoses
were classified as serious.
 Mental disorders are associated with a general pattern of disadvantaged
social status, including being female, unmarried, and having low
socioeconomic status.
 The finding that non-Hispanic black and Hispanic individuals have
significantly lower risk of disorders is inconsistent with this general pattern,
but the same relationship was found in the baseline NCS.
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Other important findings from the NCS-R survey:
 Many disorders start early, half of all lifetime cases start by 14 years
and three-fourths by 24 years. The age of onset varies by disorder:
 Median age of onset for anxiety disorders (11 yrs.)
 Median age of onset for impulse control disorders
(11 yrs.)
 Median age for substance use disorders (20 yrs.)
 Median age for mood disorders (30 yrs.)
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Other important findings from the NCS-R survey:
 Disorders that occur (have their onset) later in life are generally comorbid
(secondary) conditions.
 Mental disorders are distinct from chronic physical disorders because they
have their strongest foothold in youth, with substantially lower risk among
people who have matured out of the high-risk age range.
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A few words on substance use disorders (including alcohol use):
 Alcohol dependence is the most common substance use disorder by far
compared with any other drug
 The dependence rate on all other drugs combined is about half the
dependence rate on alcohol
 Those dependent on other drugs are usually also dependent on alcohol
(We will consider SUDs later on in the semester both as independent disorders
as well as very common co-occurring conditions with SMIs)
Mental Health Policy II
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NCS-R
Alcohol Abuse 13.2%
Alcohol Dependence 5.4
Drug Abuse 7.9
Drug Dependence 3.0
Any Substance Use Disorder 14.6
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There was a big problem with the NCS-R data and findings that likely reflect
the problems with the DSM (and ECA):
Are this many people really mentally ill in the US and in need of
treatment????
Implications:
26% (~60 million) of the United States population needs mental health
treatment in a given year?
46% (~135 million) of the United States population needs mental health
treatment in their lifetime?
A prospective study found that, by age 32, 50% of the general population had
qualified for an anxiety disorder, 40% for a depression, and 30% for alcohol
abuse or dependence (Moffitt et al. 2010). Imagine what the rates will be like
by the time these people hit age 50, or 65, or 80. In this brave new world
psychiatric overdiagnosis, few will get through life without a mental disorder.
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Because diagnoses have no real biological or neurological referrants, they are subject to
cultural influences and contexts. Important influences on diagnostic inflation include:
1. The widespread appeal of the DSM is in its clear definitions, which allow people to
diagnose themselves and family members.
2. It is fairly easy to meet criteria for one or another DSM diagnosis. The definitional
thresholds may be set too low.
3. The pharmaceutical industry has proven to be fairly unsuccessful in developing new
and improved medications. But it is wonderfully effective at marketing existing wares
and is an important engine in overdiagnosis and the spread of psychiatric epidemics.
4. Patient and family advocacy groups have played an important role in calling attention
to neglected needs; in lobbying for clinical, school, and research programs; and in
reducing stigma and promoting group and community. support.
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5. It is no accident that the recent epidemics have mostly occurred in the childhood
disorders. There are two contributing factors. The first is the push by drug companies
into this new market. The second is that the provision of special educational services
often requires that there be a DSM diagnosis.
6. The media feed off of and feed into the public interest in mental disorder. This
happens in two ways. Periodically, the media become obsessed with one or another
celebrity whose public meltdown seems related to a real or imagined mental disorder.
The mental disorder is then endlessly dissected by the media.
7. We live in a society that is perfectionistic in its expectations and intolerant of what
were previously considered to be normal and expectable distress and individual
differences.
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Maybe if we adjusted for severity, the numbers would make more sense (this is
what is meant by dimensionality in the Blashfield article)…. Criteria for severe
impairment in the NCS-R:
 Bipolar I or substance dependent with physiological dependence
(tolerance or withdrawal) or
 Making a suicide attempt and having any Axis I disorder or
 At least 2 areas of role functioning severely impaired or
 GAF score of 50 or lower (suicidal ideation, severe obsessions,
frequent shoplifting, no friends, unable to keep a job)
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2
50
 Criteria for moderate impairment in the NCS-R
 Substance dependent without physiological dependence or
 At least moderate impairment in any area of role functioning
 All other disorders classified as mild…
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2
51
NCS-R
Serious/Severe 7.7% (29.6)
Moderate 9.4 (35.7)
Mild 9.2 (34.9)
All 26.3%
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2
52
 So, viewed in this way, about 8% of the US adult population (18 years of
age or older) needs mental health treatment…
 This is still a large number - ~26 million people
 So the people with the most severe manifestations of the disorder get
treated right?
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2
53
 Yes and no… on the one hand, disorder severity is strongly related to
treatment …
 In the US, 52% of those with severe disorders, 34% of those with moderate,
22% of those with mild, and 8% of those with no disorder…
 Demand for treatment is related to severity, presumably mediated by
distress and impairment…
But….
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2
54
 Even though the proportion of non-cases in treatment is small (no
diagnosis!) the fact that noncases make up the majority of the population
means that noncases constitute a meaningful fraction of all people in
treatment…
 Either the majority or a near majority of people in treatment in each country
(WHO study) are either noncases or mild cases…
 AND… in developed countries (including the US) 35% to 50% of the serious
cases are untreated
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2
55
 Among those cases that do get treatment, at least half receive inadequate
care (even when “adequate” was defined as >= 2 visits to a treatment
provider…
 Only one-third of treatments meet minimal standards of adequacy based on
evidence-based treatment guidelines.
 People with SMI also get poorer medical care when they are able to access
it.
 Lower rates of treatment among racial and ethnic minorities, the elderly,
low-income, those with co-occurring substance abuse, and low education.
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2
56
 The proportion of NCS-R respondents who reported 12-month mental health
service use (17.9%) is higher than the value found a decade earlier in the
baseline NCS (13.3%) and the value found a decade before that in the
Epidemiologic Catchment Area Study (12.3%).
 The greatest part of this expansion occurred in the general medical sector.
General physicians often act as gatekeepers responsible for initiating mental
health treatments themselves and for deciding whom to triage for specialty care.
 Only a few patients treated in the GM sector receive minimally adequate care…
but presumably involve provider factors (eg, competing demands, inadequate
reimbursements for treating mental disorders, and less training and experience in
treating mental disorders) and patient factors (eg, worse compliance with
treatments than in MHS sectors).
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2
57
 System barriers that constrain reallocation:
 In US, decentralized system, limiting access to psychotherapists among
the middle class, does not translate into more care for the poor (not the
same pot of money or resources).
 Differences in perceived need despite objective severity drive
treatment.
 Differences in access associated with insurance coverage and financial
resources (is ACA changes this?).
 No obvious strategy (treating mild cases may prevent progression to
more severe disorders – ACA does emphasize prevention and parity).
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2
58
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2
59
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2
60
Question: What would you do to more rationally allocate
treatment? What system changes or policies would you
put in place?
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2
61
17.8
12.2
26.4
12
18.4
9.1
8.2
14.9
9.2
20.5
16.9
4.7
8.8 9.1
4.3
0
5
10
15
20
25
30
C
olum
bia
M
exico
U
nited
States
Belgium
France
G
erm
any
Italy
N
etherlands
Spain
U
kraine
Lebanon
N
igeria
Japan
C
hina
Shanghai
12-month prevalence – any disorder
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
We will talk more about international comparisons, but based on NCS-R data
and comparable data collected in other countries…..
9/1/15 Week 2
62
 American culture with emphasis on independence
leads to more isolation and loneliness?
 Higher degree of stress?
 Concepts used to describe mental illness in English
do not translate to other cultures?
 More used to surveys and polls in this country and
hence greater openness?
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2
63
*****First Short Critique Due September 8th at 5:00PM. *****
Discuss attempts to define mental illness, including the DSM-5, controversial
issues with these definitions, and alternative ways in which we might define
mental illness. You can hone in on a single diagnosis such as Asperger’s, ADHD,
removal of the bereavement exclusion from Major Depression, etc. if you prefer.
Mental Health Policy II
Definitions, Epidemiology, Service Use and Access
9/1/15 Week 2

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Mental Health Policy - Defining mental illness, epidemiology, service use, and access

  • 1. 1 Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 2. 2 Mental Health Policy II Definitions, Epidemiology, Service Use and Access The D.S.M. would do well to recognize that a broken heart is not a medical condition, and that medication is ill-suited to repair some tears. Time does not heal all wounds, closure is a fiction, and so too is the notion that God never asks of us more than we can bear. Enduring the unbearable is sometimes exactly what life asks of us. But there is a sweetness even to the intensity of this pain I feel. It is the thing that holds me still to my son. And yes, there is a balm even in the pain. I shall let it go when it is time, without reference to the D.S.M., and without the aid of a pill. - Ted Gup fellow of the Edmond J. Safra Center for Ethics at Harvard University writing on the loss of his son to a drug overdose and the pathologizing of grief in the DSM 5. (NY Times, April 2013) 9/1/15 Week 2
  • 3. 3  Nature versus nurture controversy…. Is mental illness inherited, caused by stressful environmental conditions, or an interaction of both?  What are the implications for a person who is diagnosed as having a “mental disease”? (A “schizophrenic”)  How important are cultural determinants and social determinants (poverty, racism, sexism)?  Is the term “mental illness” even logical? Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 4. 4 1. Strictly speaking, disease or illness can affect only the body; hence, there can be no mental illness. 2. “Mental illness” is a metaphor. Minds can be “sick” only in the sense that jokes are “sick” or economies are “sick.” 3. Psychiatric diagnoses are stigmatizing labels, phrased to resemble medical diagnoses and applied to persons whose behavior annoys or offends others. 4. Those who suffer from and complain of their own behavior are usually classified as “neurotic”; those whose behavior makes others suffer, and about whom others complain, are usually classified as “psychotic.” 5. 5. Mental illness is not something a person has, but is something he does or is. Szasz, Thomas S. (2011-07-12). The Myth of Mental Illness: Foundations of a Theory of Personal Conduct (p. 267). HarperCollins. Kindle Edition. Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 5. 5 Mental Health Policy II Definitions, Epidemiology, Service Use and Access Should we adopt a broad definition of disease that includes all the following possibilities to understand the cause(s) of mental illness? Disease: any condition that impairs normal functioning. Types: 1) Pathogenic (common cold) 2) Deficiency (anemia) 3) Hereditary (Down’s Syndrome) 4) Physiological--malfunction of body organ (“chemical imbalance”) asthma-lungs diabetes-pancreas addiction, schizophrenia, bipolar disorder-brain 9/1/15 Week 2 5
  • 6. 6 Mental Health Policy II Definitions, Epidemiology, Service Use and Access Fundamental changes in brain help “explain” continued drug use and relapse. 9/1/15 Week 2
  • 7. 7 Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2 …the fact that addiction is associated with neurobiological changes is not, in itself, proof that the addict is unable to choose. Robert Downey Jr. was once a poster boy for drug excess. “It’s like I have a loaded gun in my mouth and my finger’s on the trigger, and I like the taste of gunmetal,” he said. It seemed only a matter of time before he would meet a horrible end. But Downey entered rehab and decided to change his life. Why did Downey use drugs? Why did he decide to stop and to remain clean and sober? An examination of his brain, no matter how sophisticated the probe, could not tell us why and perhaps never will. The key problem with neurocentrism is that it devalues the importance of psychological explanations and environmental factors, such as familial chaos, stress, and widespread access to drugs, in sustaining addiction. Satel, Sally; Lilienfeld, Scott O. (2013-05-16). Brainwashed: The Seductive Appeal of Mindless Neuroscience . Basic Books. Kindle Edition.
  • 8. 8  Evidence does suggest an inherited component for some disorders:  Schizophrenia spectrum and other psychotic disorders  Bipolar disorder  Major depressive disorder  Borderline personality disorder  ASP  Alcoholism (stronger genetic link for men)  But none are 100% heritable and the genetic component is less clear for other disorders such as the phobias. Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2 8
  • 9. 9  Other models of mental illness (all have modest support but none can explain all mental illnesses):  Psychosocial development (psychoanalytic psychology; “schizophrenegenic mother”)  Learning theory (at first, purely behavioral and then cognitive behavioral implications)  Social-stress (stressful conditions cause psychological breakdowns particularly in pre- disposed individuals – interaction idea)  Labeling theory – (deviant behaviors labeled as illness, mental illness as a social construct – Szasz) Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2 9
  • 10. 10 Mental Health Policy II Definitions, Epidemiology, Service Use and Access Alas, we have reviewed dozens of definitions of mental disorder (and helped to write the one in DSM-IV) and must admit that none have much practical value (Wakefield 1992, Wakefield & First 2003). Historically, conditions have become mental disorders by accretion and practical necessity, not because they met some independent set of abstract and operationalized definitional criteria. Indeed, the concept of mental disorder is so amorphous, protean, and heterogeneous that it inherently defies definition— creating a hole at the center of psychiatric classification. The common themes in the definition of mental disorder are distress, disability, dyscontrol, and dysfunction but these are very imprecise and nonspecific markers with little practical value. 9/1/15 Week 2 10
  • 11. 11 Mental Health Policy II Definitions, Epidemiology, Service Use and Access As one illustration, it has become crystal clear that there is no one prototype “schizophrenia” waiting to be explained with one incisive and sweeping biological model. Instead, a painful process of promising false starts has taught us there is no single gene, or small subset of genes, to account for schizophrenia. … schizophrenia is rather a group of disorders, or perhaps better, a mob. There may eventually turn out to be 20 or 50 or 200 kinds of schizophrenia, and its definitions are necessarily arbitrary constructs. There is no clear right way to diagnose this gang or even much agreement on what the validators should be and how they should be applied. (Frances and Widiger paper, no longer assigned) 9/1/15 Week 2
  • 12. 12 Mental Health Policy II Definitions, Epidemiology, Service Use and Access Pragmatic concerns must play so central a role because the DSM is an official system of classification that has a huge (perhaps excessive) influence on how everything works in the mental health world: who gets diagnosed, how they are treated, who pays for it, whether disability is appropriate, and whether someone can be involuntarily committed, released from legal responsibility, or sue for damages. Fads in diagnosis come and go and have been with us as long as there has been psychiatry. The fads meet a deeply felt need to explain, or at least to label, what would otherwise be unexplainable human suffering and deviance. In recent years the pace has picked up, with false epidemics coming in bunches that involve an ever-increasing proportion of the population. We are now in the midst of at least four such epidemics: autism, attention deficit, childhood bipolar disorder, and paraphilia not otherwise specified. 9/1/15 Week 2
  • 13. 13 History of the DSM • 1952 – First edition • 1968 – Second Edition DSM-II – only 136 pages • 1980 – DSM-III published after work had begun in 1974 • 1987 – Publication of DSM-III-R after APA appointed a work group to revise and correct DSM-III • 1994 – Publication of DSM-IV • 2000 – Publication of DSM-IV-Text Revision • 2013 – Publication of DSM-5 See Blashfield, Keeley et al. (2014) on syllabus. Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 14. 14 Mental Health Policy II Definitions, Epidemiology, Service Use and Access  Prevalences studies of national scope were not done prior to the 1980s.  Psychiatry was dominated by psychoanalytic/psychodynamic thinking as embodied in DSM-1 and DSM-2, which focused on etiological understanding and not symptoms or classifications.  Administering a structured survey to thousands of people using lay interviewers was not possible with DSM-2 because the specific criteria for a given disorder were not available in DSM-2. 9/1/15 Week 2
  • 15. 15 Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 16. 16 Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 17. 17 Mental Health Policy II Definitions, Epidemiology, Service Use and Access • DSM-III was a radical departure from DSM-2 • Removed focus from etiology to symptoms and classification and increased number of diagnoses. • Coordinated with development of ICD-9. 9/1/15 Week 2
  • 18. 18 Mental Health Policy II Definitions, Epidemiology, Service Use and Access  DSM-5 continues the trend. It is 947 pages long and has over 500 diagnostic conditions.  Use of the DSM-5 could result in higher estimated rates of mental illness as it requires fewer symptoms for shorter durations to meet diagnostic thresholds.  The abandonment of the Roman numeral (e.g., III, IV) was intentional with the goal being more frequent revisions as scientific findings emerge. The revisions will be labeled 5.1, 5.2. etc. 9/1/15 Week 2
  • 19. 19 Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 20. 20 Mental Health Policy II Definitions, Epidemiology, Service Use and Access  Per Mayes and Horwitz, and Blashfield et al.:  The basic transformation in the DSM-III was its development and use of a model that equated visible and measurable symptoms with the presence of diseases.  This symptom-based model allowed psychiatry to develop a standardized system of measurement.  Such a standardized system benefited numerous interests. It allowed research-oriented psychiatrists (“neo-Kraepelinians”), a small but highly influential group in the profession, to measure mental illness in reliable and reproducible ways.  It also helped silence the critics of the previous system, who claimed that mental illnesses could not be defined in any objective way (e.g., Szaz – but he maintained his criticism). 9/1/15 Week 2
  • 21. 21 Mental Health Policy II Definitions, Epidemiology, Service Use and Access  Per Mayes and Horwitz:  For clinicians, the new diagnostic system legitimized claims to be treating real diseases and, most importantly, allowed them to obtain reimbursement from third party insurers.  Because the manual defined illnesses solely through symptoms without regard to causes, it was theory-neutral and could be used by clinicians of all theoretical persuasions.  The symptom-based manual also met the needs of pharmaceutical companies to have specific diseases for their products to treat. 9/1/15 Week 2
  • 22. 22 Mental Health Policy II Definitions, Epidemiology, Service Use and Access  DSM-III came about, in part, as a result of many pressures on the psychiatric profession:  Psychiatry’s marginal status within the medical profession  Increasing reluctance of insurance companies and the government to reimburse long-term talk therapy  The need to treat formerly institutionalized seriously mentally ill persons in the community, the growing influence of medication treatments  Growing professional threat from non-physicians such as clinical psychologists, counselors, and social workers. 9/1/15 Week 2
  • 23. 23 Mental Health Policy II Definitions, Epidemiology, Service Use and Access  The confluence of these pressures led to a new DSM that fundamentally redefined what mental disorders were and how they should be identified, diagnosed, and treated.  “By intent and careful plan the developers of DSM-III sought to bring about a revolution in how mental health professionals thought about and practiced psychiatric diagnosis. On many levels, the revolution succeeded remarkably well” (Kirk & Kutchins, 1992, p. 11).  American psychiatry in the late twentieth century moved from a state of “brainlessness” to one of “mindlessness.”  What is of particular interest to social scientists is the extent to which politics and the underlying economics of psychiatric practice permeated the DSM-III’s creation. 9/1/15 Week 2 23
  • 24. 24 Mental Health Policy II Definitions, Epidemiology, Service Use and Access In short, a powerful quartet of voices came together during the 1980’s eager to inform the public that mental disorders were brain diseases. • Pharmaceutical companies provided the financial muscle (69% of the DSM- 5 study group contributors had/have direct ties to the pharmaceutical industry). • The APA and psychiatrists at top medical schools conferred intellectual legitimacy upon the enterprise. • The NIMH [National Institute of Mental Health] put the government’s stamp of approval on the story. • NAMI provided moral authority. 9/1/15 Week 2
  • 25. 25 Mental Health Policy II Definitions, Epidemiology, Service Use and Access  With the medicalization of psychiatry came an increased emphasis on pharmacology rather than talk therapy.  DSM-III standardized the diagnostic classification scheme for mental illnesses and disorders but did not include treatment guidelines.  By virtue of its Kraepelinian orientation, however, it allowed pharmaceutical companies to market their products for a growing number of specific, symptom-based disease entities (Healy, 1997).  The DSM-III unintentionally positioned psychopharmacology on a growth trajectory that various institutions—insurance companies, managed care organizations, pharmaceutical companies, and the government—propelled significantly in subsequent years as they responded to the DSM-III’s new diagnostic guidelines and research incentives. 9/1/15 Week 2
  • 26. 26 Mental Health Policy II Definitions, Epidemiology, Service Use and Access  The DSM-III allowed for research on the prevalence of disorders because it provided specific criteria for assessing a disorder.  The criteria could be coded into questions on a survey form that could be administered by trained non-professionals (lay interviewers).  The first survey form was the Diagnostic Interview Schedule (DIS) used in the ECA study.  Currently, the Composite International Diagnostic Interview (CIDI) is the instrument in current use in the WHO and NCS-R studies… NESARC uses another instrument (AUDADIS). 9/1/15 Week 2
  • 27. 27 Mental Health Policy II Definitions, Epidemiology, Service Use and Access The assumptions underlying the symptom-oriented focus of the DSM-III (and every version of the DSM since that time) has had some problematic implications:  Although the main purpose of the introduction of a separate axis for personality disorders (Axis II) in DSM–III was to stimulate research on personality disorders, many researchers subsequently made the implicit assumption that Axis I and Axis II are independent. Moreover, Axis II disorders were considered less important or severe. This issue no longer applies to the DSM-5 since the axial system has been abandoned.  Much research on DSM has been inspired by another implicit assumption that each disorder has its own relatively unique etiology and that one therefore also can and should develop a relatively specific treatment for each disorder. This assumption has led to recent conflicts between the APA and NIMH, which has developed its own independent set of criteria. 9/1/15 Week 2
  • 28. 28 Mental Health Policy II Definitions, Epidemiology, Service Use and Access  Most treatment studies and treatment guidelines have focused on the efficacy and effectiveness of disorder– specific treatments, and not on the effect of a particular treatment for different disorders or particular aspects of treatment processes.  Studies on gene–environment correlations strongly suggest that individuals vulnerable to depression in part create their own (stressful) environments and there is high comorbidity between depression and Axis II disorders, particularly dependent, borderline, and obsessive-compulsive personality disorder, making it highly unlikely that depression and personality disorders are independent 9/1/15 Week 2
  • 29. 29 Mental Health Policy II Definitions, Epidemiology, Service Use and Access  Multi-comorbidity is an issue generally with our current diagnostic systems.  Research has consistently shown that comorbidity between depression, anxiety and other Axis I disorders is the rule rather than the exception, arguing against the assumption that depression and other disorders are relatively distinct.  Epidemiologic and clinical studies have shown extremely high rates of comorbidities among the disorders, undermining the hypothesis that the syndromes represent distinct etiologies. (Dohrenwend’s g?)  Widespread use of “NOS” because the original diagnostic criteria for each diagnosis were too narrow (to improve reliability). They do not reflect the messy clinical reality. NOS has been eliminated in DSM-5 and replaced with “other specified” and “unspecified”.  Patients with symptoms that straddled diagnoses such as “schizoaffective disorder”. 9/1/15 Week 2
  • 30. 30 Mental Health Policy II Definitions, Epidemiology, Service Use and Access • The converse of the multi-comorbidity issue is that people with the same diagnosis can be very heterogeneous because of the mix and match set of symptoms necessary for diagnosis: Like essentially all heterogeneous, polygenic illnesses, psychiatric disorders are poorly captured as categories (which assume significant discontinuities between ‘well’ and ‘ill’ conditions and between any two disorders). DSM categories have the bizarre property of being both too broad (in the sense that they identify remarkably heterogeneous populations) and too narrow (in the sense that, given the large number of arbitrary DSM diagnostic silos, many if not most patients with a single DSM diagnosis actually qualify for two or more.) (Casey, B. et al., (2013). DSM-5 and RDoC: progress in psychiatry research? Neuroscience, 14, 810-814) 9/1/15 Week 2
  • 31. 31 Mental Health Policy II Definitions, Epidemiology, Service Use and Access  It became necessary in the 1970s to facilitate diagnostic agreement among clinicians, scientists and regulatory authorities given the need to match patients with newly emerging pharmacologic treatments…  While it is true that no system based entirely on clinical description can match the levels of diagnostic agreement made possible by objective medical tests, there were no good alternatives for psychiatry when DSM-III was published in the 1980s. Indeed, even today objective tests and biomarkers for mental disorders remain research goals rather than clinical tools.  The DSM-III-R and DSM-IV revisions remained close to the DSM-III approach, in part because of the dearth of new scientific information. As a result, diagnosis in the DSM-III, DSM-III-R, and DSM-IV are best understood as useful placeholders, based on careful description, but not on deeper understandings.  The use of symptom-based clusters as indicating diagnosis remains a characteristic of the just-published DSM-5. 9/1/15 Week 2
  • 32. 32 Mental Health Policy II Definitions, Epidemiology, Service Use and Access The goal of this new manual, as with all previous editions, is to provide a common language for describing psychopathology. While DSM has been described as a “Bible” for the field, it is, at best, a dictionary, creating a set of labels and defining each. The strength of each of the editions of DSM has been “reliability” – each edition has ensured that clinicians use the same terms in the same ways. The weakness is its lack of validity. Unlike our definitions of ischemic heart disease, lymphoma, or AIDS, the DSM diagnoses are based on a consensus about clusters of clinical symptoms, not any objective laboratory measure. In the rest of medicine, this would be equivalent to creating diagnostic systems based on the nature of chest pain or the quality of fever. Indeed, symptom-based diagnosis, once common in other areas of medicine, has been largely replaced in the past half century as we have understood that symptoms alone rarely indicate the best choice of treatment. Patients with mental disorders deserve better. Thomas Insel – NIMH Director (April 2013) http://www.nimh.nih.gov/about/director/2013/transforming-diagnosis.shtml 9/1/15 Week 2
  • 33. 33 Mental Health Policy II Definitions, Epidemiology, Service Use and Access Insel walked this back within a week or so and issued a joint statement President of APA: “The DSM-5 represents the best information currently available for clinical diagnosis of mental disorders. Patients, families, and insurers can be confident that effective treatments are available and that the DSM is the key resource for delivering the best available care. The National Institute of Mental Health (NIMH) has not changed its position on DSM-5.” Nevertheless, NIMH has come out with its own set of criteria called the Research Domain Criteria (RDoC). These criteria do not assume a diagnosis first but instead start with how functioning is impaired in given domains: “Rather than starting with an illness definition and seeking its neurobiological underpinnings, RDoC begins with current understandings of behavior-brain relationships and links them to clinical phenomena.” http://www.nimh.nih.gov/research-priorities/rdoc/nimh-research-domain-criteria- rdoc.shtml#toc_matrix 9/1/15 Week 2
  • 34. 34 Mental Health Policy II Definitions, Epidemiology, Service Use and Access  Major prevalence studies over the last 3 decades:  Epidemiological Catchment Area Study (1980s)  National Comorbidity Survey (1990s)  National Comorbidity Survey - Replication (2000s)  National Epidemiological Survey on Alcohol and Related Conditions (NESARC) (2000s) – oversamples minorities; includes modules to assess personality disorders; will be administered longitudinally to track progression 9/1/15 Week 2
  • 35. 35 Mental Health Policy II Definitions, Epidemiology, Service Use and Access Major prevalence studies over the last 3 decades:  National Survey on Drug Use and Health (annual; focuses on substance use but also asks a limited number of questions about mental health symptoms and treatment access).  Two additional minority-specific psychiatric epidemiology studies are linked to the NCS-R: the National Survey of African Americans (NSAA) and the National Latino and Asian American Study (NLAAS).  WHO – World Mental Health Surveys (includes NCS-R in the US) in 31 countries. 9/1/15 Week 2
  • 36. 36  Prevalence rates across studies vary with the ECA study generally having the lowest rates  All studies have yielded surprisingly high prevalence rates …..more people have at least one lifetime DSM disorder than anyone expected  Per the NCS-R, the chance of having at least one DSM disorder in your lifetime is close to 50% Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 37. 37 ECA NCS NCS-R Affective Disorder 7.1% 11.1% 9.6% Anxiety Disorder 13.1 18.7 18.2 Substance Use* 6.4 11.3 3.8 Any Disorder 19.5 23.4 26.2 *ECA estimate is for 6 month prevalence Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 38. 38 Rates across the 3 surveys vary but are difficult to compare because:  Different diagnostic systems  DSM-III (ECA)  DSM-IIIR (NCS)  DSM-IV (NCS-R)  Different sampling strategies  ECA was not a national sample (5 sites)  NCS and NCS-R were national samples  Change in instrumentation and protocol  Better use of stem questions  Computer assisted interviewing (reduces error) Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 39. 39 Other important findings from the NCS-R survey:  The three most prevalent 12-month disorders found by the NCS-R were specific phobia (9%), social phobia (7%), and major depressive disorder (7%).  The most prevalent 12-month disease classes are anxiety disorders (18%), mood disorders (10%), impulse-control disorders (9%), and substance use disorders (4%).  The most prevalent lifetime disorders are anxiety disorders (29%), mood disorders (21%), impulse-control disorders (25%), and substance use disorders (15%). Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 40. 40 Other important findings from the NCS-R survey:  The mental disorders with the highest proportion of seriously disabling 12- month cases are: bipolar disorder (83%); drug dependence (57%); and obsessive-compulsive disorder (51%).  Impulse-control disorders, which have been neglected in most previous epidemiological studies of adults, have a greater proportion at the serious level than either anxiety disorders or substance use disorders. Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 41. 41 Other important findings from the NCS-R survey:  Severity was strongly related to comorbidity; 9.6% of respondents with 1 diagnosis, 25.5% with 2 diagnoses, and 49.9% with 3 or more diagnoses were classified as serious.  Mental disorders are associated with a general pattern of disadvantaged social status, including being female, unmarried, and having low socioeconomic status.  The finding that non-Hispanic black and Hispanic individuals have significantly lower risk of disorders is inconsistent with this general pattern, but the same relationship was found in the baseline NCS. Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 42. 42 Other important findings from the NCS-R survey:  Many disorders start early, half of all lifetime cases start by 14 years and three-fourths by 24 years. The age of onset varies by disorder:  Median age of onset for anxiety disorders (11 yrs.)  Median age of onset for impulse control disorders (11 yrs.)  Median age for substance use disorders (20 yrs.)  Median age for mood disorders (30 yrs.) Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 43. 43 Other important findings from the NCS-R survey:  Disorders that occur (have their onset) later in life are generally comorbid (secondary) conditions.  Mental disorders are distinct from chronic physical disorders because they have their strongest foothold in youth, with substantially lower risk among people who have matured out of the high-risk age range. Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 44. 44 A few words on substance use disorders (including alcohol use):  Alcohol dependence is the most common substance use disorder by far compared with any other drug  The dependence rate on all other drugs combined is about half the dependence rate on alcohol  Those dependent on other drugs are usually also dependent on alcohol (We will consider SUDs later on in the semester both as independent disorders as well as very common co-occurring conditions with SMIs) Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 45. 45 NCS-R Alcohol Abuse 13.2% Alcohol Dependence 5.4 Drug Abuse 7.9 Drug Dependence 3.0 Any Substance Use Disorder 14.6 Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 46. 46 There was a big problem with the NCS-R data and findings that likely reflect the problems with the DSM (and ECA): Are this many people really mentally ill in the US and in need of treatment???? Implications: 26% (~60 million) of the United States population needs mental health treatment in a given year? 46% (~135 million) of the United States population needs mental health treatment in their lifetime? A prospective study found that, by age 32, 50% of the general population had qualified for an anxiety disorder, 40% for a depression, and 30% for alcohol abuse or dependence (Moffitt et al. 2010). Imagine what the rates will be like by the time these people hit age 50, or 65, or 80. In this brave new world psychiatric overdiagnosis, few will get through life without a mental disorder. Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 47. 47 Because diagnoses have no real biological or neurological referrants, they are subject to cultural influences and contexts. Important influences on diagnostic inflation include: 1. The widespread appeal of the DSM is in its clear definitions, which allow people to diagnose themselves and family members. 2. It is fairly easy to meet criteria for one or another DSM diagnosis. The definitional thresholds may be set too low. 3. The pharmaceutical industry has proven to be fairly unsuccessful in developing new and improved medications. But it is wonderfully effective at marketing existing wares and is an important engine in overdiagnosis and the spread of psychiatric epidemics. 4. Patient and family advocacy groups have played an important role in calling attention to neglected needs; in lobbying for clinical, school, and research programs; and in reducing stigma and promoting group and community. support. Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 48. 48 5. It is no accident that the recent epidemics have mostly occurred in the childhood disorders. There are two contributing factors. The first is the push by drug companies into this new market. The second is that the provision of special educational services often requires that there be a DSM diagnosis. 6. The media feed off of and feed into the public interest in mental disorder. This happens in two ways. Periodically, the media become obsessed with one or another celebrity whose public meltdown seems related to a real or imagined mental disorder. The mental disorder is then endlessly dissected by the media. 7. We live in a society that is perfectionistic in its expectations and intolerant of what were previously considered to be normal and expectable distress and individual differences. Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 49. 49 Maybe if we adjusted for severity, the numbers would make more sense (this is what is meant by dimensionality in the Blashfield article)…. Criteria for severe impairment in the NCS-R:  Bipolar I or substance dependent with physiological dependence (tolerance or withdrawal) or  Making a suicide attempt and having any Axis I disorder or  At least 2 areas of role functioning severely impaired or  GAF score of 50 or lower (suicidal ideation, severe obsessions, frequent shoplifting, no friends, unable to keep a job) Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 50. 50  Criteria for moderate impairment in the NCS-R  Substance dependent without physiological dependence or  At least moderate impairment in any area of role functioning  All other disorders classified as mild… Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 51. 51 NCS-R Serious/Severe 7.7% (29.6) Moderate 9.4 (35.7) Mild 9.2 (34.9) All 26.3% Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 52. 52  So, viewed in this way, about 8% of the US adult population (18 years of age or older) needs mental health treatment…  This is still a large number - ~26 million people  So the people with the most severe manifestations of the disorder get treated right? Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 53. 53  Yes and no… on the one hand, disorder severity is strongly related to treatment …  In the US, 52% of those with severe disorders, 34% of those with moderate, 22% of those with mild, and 8% of those with no disorder…  Demand for treatment is related to severity, presumably mediated by distress and impairment… But…. Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 54. 54  Even though the proportion of non-cases in treatment is small (no diagnosis!) the fact that noncases make up the majority of the population means that noncases constitute a meaningful fraction of all people in treatment…  Either the majority or a near majority of people in treatment in each country (WHO study) are either noncases or mild cases…  AND… in developed countries (including the US) 35% to 50% of the serious cases are untreated Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 55. 55  Among those cases that do get treatment, at least half receive inadequate care (even when “adequate” was defined as >= 2 visits to a treatment provider…  Only one-third of treatments meet minimal standards of adequacy based on evidence-based treatment guidelines.  People with SMI also get poorer medical care when they are able to access it.  Lower rates of treatment among racial and ethnic minorities, the elderly, low-income, those with co-occurring substance abuse, and low education. Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 56. 56  The proportion of NCS-R respondents who reported 12-month mental health service use (17.9%) is higher than the value found a decade earlier in the baseline NCS (13.3%) and the value found a decade before that in the Epidemiologic Catchment Area Study (12.3%).  The greatest part of this expansion occurred in the general medical sector. General physicians often act as gatekeepers responsible for initiating mental health treatments themselves and for deciding whom to triage for specialty care.  Only a few patients treated in the GM sector receive minimally adequate care… but presumably involve provider factors (eg, competing demands, inadequate reimbursements for treating mental disorders, and less training and experience in treating mental disorders) and patient factors (eg, worse compliance with treatments than in MHS sectors). Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 57. 57  System barriers that constrain reallocation:  In US, decentralized system, limiting access to psychotherapists among the middle class, does not translate into more care for the poor (not the same pot of money or resources).  Differences in perceived need despite objective severity drive treatment.  Differences in access associated with insurance coverage and financial resources (is ACA changes this?).  No obvious strategy (treating mild cases may prevent progression to more severe disorders – ACA does emphasize prevention and parity). Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 58. 58 Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 59. 59 Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 60. 60 Question: What would you do to more rationally allocate treatment? What system changes or policies would you put in place? Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 61. 61 17.8 12.2 26.4 12 18.4 9.1 8.2 14.9 9.2 20.5 16.9 4.7 8.8 9.1 4.3 0 5 10 15 20 25 30 C olum bia M exico U nited States Belgium France G erm any Italy N etherlands Spain U kraine Lebanon N igeria Japan C hina Shanghai 12-month prevalence – any disorder Mental Health Policy II Definitions, Epidemiology, Service Use and Access We will talk more about international comparisons, but based on NCS-R data and comparable data collected in other countries….. 9/1/15 Week 2
  • 62. 62  American culture with emphasis on independence leads to more isolation and loneliness?  Higher degree of stress?  Concepts used to describe mental illness in English do not translate to other cultures?  More used to surveys and polls in this country and hence greater openness? Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2
  • 63. 63 *****First Short Critique Due September 8th at 5:00PM. ***** Discuss attempts to define mental illness, including the DSM-5, controversial issues with these definitions, and alternative ways in which we might define mental illness. You can hone in on a single diagnosis such as Asperger’s, ADHD, removal of the bereavement exclusion from Major Depression, etc. if you prefer. Mental Health Policy II Definitions, Epidemiology, Service Use and Access 9/1/15 Week 2