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Regional Program of Action and 
Demonstration of Sustainable Alternatives to 
DDT for Malaria Vector Control in Mexico 
and Central America 
Third Biennial International Waters 
Conference 
Salvador, Bahia, Brazil. 
20-25 June 2005
WWHHOO oonn DDDDTT uussee iinn ddiisseeaassee vveeccttoorr ccoonnttrrooll uunnddeerr 
tthhee SSttoocckkhhoollmm CCoonnvveennttiioonn oonn PPOOPP’’ss ((MMaayy--22000044)) 
““The Convention reconizes three iimmppoorrttaanntt ffaaccttss:: 
11.. ...... TToo mmaannttaaiinn tthhiieerr rreelliiaannccee oonn tthhee uussee ooff DDDDTT ffoorr 
iinnddoooorr rreessiidduuaall sspprraayyiinngg ttoo ccoonnttrrooll iinnsseecctt vveeccttoorrss,, 
ppaarrttiiccuullaarrllyy mmaallaarriiaa vveeccttoorrss,, ...... 
22.. AA nneeeedd ttoo aacceelleerraattee rreesseeaarrcchh aanndd ddeevveellooppmmeenntt ooff 
ssaaffee,, eeffffeeccttiivvee aanndd aaffffoorrddaabbllee aalltteerrnnaattiivveess ttoo 
DDDDTT,, ........ 
33.. AA lloonnggeerr--tteerrmm ggooaall ooff rreedduucciinngg tthhee oovveerr--rreelliiaannccee ooff 
vveeccttoorr ccoonnttrrooll pprrooggrraammmmeess oonn ppeessttiicciiddeess iinn 
ggeenneerraall,, ttoo pprrootteecctt bbootthh tthhee eeccoossyysstteemm aanndd hhuummaann 
ffrroomm nneeggaattiivvee iimmppaaccttss ooff PPOOPP ppeessttiicciiddeess..””
Dispersion of DDT in Mexico 
Levels of DDT found on 
sediments in the Lagoons 
of Zempoala, Morelos 
and its comparison with 
DDT used for malaria 
control in Mexico 
Decades 
DDT applied (t) 
Year 
DDT used in Mexico
Impact in Biota 
Concentration of DDT (ng/g) in species of the food chain in 
“La Cigüeña”, Chiapas, Mexico (2002) 
Birds = 232.50 
Fish = 24.08 Crabs = 23.84 
Sediment = 138.37
Impact in the Environment 
Total DDT (mg/kg) in superficial soil in malaria communities 
Mexico, 2002 
45,000 
40,000 
35,000 
30,000 
25,000 
20,000 
15,000 
10,000 
5,000 
0 
Total DDT 
Average (μg/kg) 
Total DDT interior 
Total DDT exterior 
Ventanilla Cigüeña Lacandona 
La Ventanilla 
La Cigüeña 
Lacandona
Impact in Humans 
DDT blood concentration in children, Mexico (mg/L) 
80 
70 
60 
50 
40 
30 
20 
10 
0 
DDT in blood in children "La Cigüeña", Chiapas 
2000 2001 2002 2003 2004 
Years 
DDD (μg/L) 
DDE (μg/L) 
DDT (μg/L) 
Mean concentration (mg/L)
Impact in Humans 
DDT, DDE and DDEms levels in breast milk of 30 Mexican 
mothers (ng/g lipid) 
Substance Sweden 
1992 
Mexico 
2004 
DDT 22 366 
DDE 227 1683 
DDEms 0.4 3.4
General Information 
PPaarrttiicciippaattiinngg 
ccoouunnttrriieess 
Belize, Costa Rica, El Salvador, Guatemala, 
Honduras, Mexico, Nicaragua, Panama 
IImmpplleemmeennttiinngg 
aaggeennccyy 
•United Nations Environment Programme 
EExxeeccuuttiinngg 
aaggeennccyy 
•Pan American Health Organization (PAHO) 
•National Governments 
FFuunnddiinngg 
PPaarrttnneerrss 
•Global Environment Facility 
•National Governments 
•PAHO 
•CEC 
Total 
7.165 
5.865 
0.654 
0.200 
US$ 13.884 
DDuurraattiioonn Three years: August 2003- July 2006
Overall Objective 
• To demonstrate that methods for malaria vector 
control without DDT or other persistent pesticides 
are replicable, cost-effective and sustainable thus 
preventing the reintroduction of DDT in the Region. 
Components 
1. Implementation of demonstration projects and 
dissemination 
2. Strengthening of national institutional capacity to control 
malaria without DDT 
3. Elimination of DDT stockpiles 
4. Coordination and management
Focal Areas 
This Project conforms with the Contaminant-based 
Operational Program No. 10 and will 
help demonstrate ways of overcoming 
barriers to the adoption of best practices 
that limit contamination of the international 
waters environment. 
The proposed activities are also consistent with 
several provisions with adopted Stockholm 
Convention on Pops.
Implementation Strategy 
• To integrate epidemiology with social sciences, 
entomology, public health, environment and 
provision of health care. 
– Epidemiological stratification with risk approach 
– Elimination of the persistent parasite 
– Ecological larvae control with social participation 
– Control of the adult mosquito with inexpensive 
techniques and low environmental impact 
– Sustained sanitation educational program aimed at the 
community
Demonstration projects 
• Demonstration projects 
in sites selected 
• Baseline assessment 
concluded 
• Community 
participation attained
Technical Manual 
Guide for the 
implementation and 
demonstration of 
sustainable alternatives 
for the integrated 
control of malaria in 
Mexico and Central 
America
Dissemination 
http://shp.paho.org/sde/ddtgef/default.aspx
The Regional Perspective of Malaria in 
Mexico and Central America in the Context 
of Epidemiological Stratification 
Tropical rainforest distribution (red) 
CONABIO map Mex. 1999 and CIESIN 
satellite image, 1995 
Areas below 800 meters above average sea level. 
Digital Elevation Model (DEM), 
USGS, 2001. 
API by first sub-national level in Mesoamerica 
(Central America Basic Indicators 2001) and 
Mexico Rates x 1000 inhabitants by second 
administrative level (SUAVE, Mex, 2001) 
The SIGEpi perspective has the purpose of standardizing, integrating, compiling and facilitate the 
interchange of digital cartographic infrastructure ( data, methods and software) as a foundation for 
analyzing geographically the data about malaria vector control and DDT residuals.
GIS-DDT-GEF Demonstration areas in 
Central America, GPS survey progress 
and instrumentation of the SIGEpi 
Model up to May 2005 
Tropical 
broad leaf 
rain forest 
Municipalities with malaria transmission in 2004 
Municipalities with malaria transmission in 1960
Costa Rica’ s GIS Local Scale 
Observation Level for Malaria 
Control 
Mosquito breeding sites 
and surrounding positive 
houses to malaria 
Progress in the 
GPS dwellings 
survey in localities 
along the border 
corridor between 
Costa Rica and 
Panama 
Paper map 
The same map in vector and raster 
digital format in SIGEpi 
GPS demonstration 
Panama 
Costa Rica
From Sketch to Digital Maps in 
Panama Showing Malaria 
Houses (red houses) 
Calculating the number of 
preventive treatments in 
the 200 meters 
surroundings
Malaria Stratification and Levels of 
Analysis in the GIS DDT Model for 
Honduras, May 2005 
API, municipal level 2002 API, locality level 2005 
Cases, intra-locality level cases 
2005… in SIGEpi 
• Identification of malaria houses per week 
• Detection of houses on transmission risk 
•100 meters proximity 
• close to a mosquito breeding site 
• Intervention programming of community actions and 
focal control and preventive treatments
Inventory of DDT and Other POPs 
Country DDT 
Other 
POPs 
Belize 13.000 0.008 
Costa Rica 8.621 0.122 
El Salvador 4.672 46.252 
Guatemala 15.058 
Honduras 3.539 12.490 
Mexico 87.000 
Nicaragua 0.003 5.647 
Panama 4.545 
Total 136.438 64.519
Organizational Chart 
Steering Committee 
8 Ministers of Health 
PAHO 
UNEP 
CEC 
CCAD 
Observers: World Bank, UNDP, 
NGOs, other cooperation agencies 
Regional Operational 
Committee 
1 Regional Coordinator 
8 Focal Points (Health) 
8 National Coordinators 
Representatives from NGOs and 
the Civil Society 
National Committee 
National Focal Point (Health) 
National Coordinator 
Environment Representative 
Agriculture Representative 
Customs or Immigration Representative 
9 Working Groups 
Demonstration Projects 
National Coordinator 
Focal Point 
Environment Representative 
Agriculture representative 
UNEP/GEF 
Implementing/Donor Agencies 
PAHO 
Executing Agency 
CEC 
Cooperation Agency 
Advisory Committee 
Universities, Research Institutions 
Civil Society, Organizations and 
NGOs with activities related to the 
project 
Advisory Committee 
One representative from each 
governmental unit 
Representatives from NGOs and the 
Civil Society
MMaallaarriiaa ccaasseess aanndd hhoouussee sspprraayyiinngg 
Cases MMééxxiiccoo 11995599 -- 22000044 Houses 
EERRAADDIICCAATTIIÓÓNN 
Y e a r 
DDT 
CCOONNTTRROOLL 
160,000 
140,000 
120,000 
100,000 
80,000 
60,000 
40,000 
20,000 
0 
59 61 63 65 67 69 71 73 75 77 79 81 83 85 87 89 91 93 95 97 99 01 03 
7,000 
6,000 
5,000 
4,000 
3,000 
2,000 
1,000 
0 
Houses 
Cases 
Piretroids

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Regional Program of Action and Demonstration of Sustianable Alternatives to DDT for Malaria Vector Control in Mexico and Central America

  • 1. Regional Program of Action and Demonstration of Sustainable Alternatives to DDT for Malaria Vector Control in Mexico and Central America Third Biennial International Waters Conference Salvador, Bahia, Brazil. 20-25 June 2005
  • 2. WWHHOO oonn DDDDTT uussee iinn ddiisseeaassee vveeccttoorr ccoonnttrrooll uunnddeerr tthhee SSttoocckkhhoollmm CCoonnvveennttiioonn oonn PPOOPP’’ss ((MMaayy--22000044)) ““The Convention reconizes three iimmppoorrttaanntt ffaaccttss:: 11.. ...... TToo mmaannttaaiinn tthhiieerr rreelliiaannccee oonn tthhee uussee ooff DDDDTT ffoorr iinnddoooorr rreessiidduuaall sspprraayyiinngg ttoo ccoonnttrrooll iinnsseecctt vveeccttoorrss,, ppaarrttiiccuullaarrllyy mmaallaarriiaa vveeccttoorrss,, ...... 22.. AA nneeeedd ttoo aacceelleerraattee rreesseeaarrcchh aanndd ddeevveellooppmmeenntt ooff ssaaffee,, eeffffeeccttiivvee aanndd aaffffoorrddaabbllee aalltteerrnnaattiivveess ttoo DDDDTT,, ........ 33.. AA lloonnggeerr--tteerrmm ggooaall ooff rreedduucciinngg tthhee oovveerr--rreelliiaannccee ooff vveeccttoorr ccoonnttrrooll pprrooggrraammmmeess oonn ppeessttiicciiddeess iinn ggeenneerraall,, ttoo pprrootteecctt bbootthh tthhee eeccoossyysstteemm aanndd hhuummaann ffrroomm nneeggaattiivvee iimmppaaccttss ooff PPOOPP ppeessttiicciiddeess..””
  • 3. Dispersion of DDT in Mexico Levels of DDT found on sediments in the Lagoons of Zempoala, Morelos and its comparison with DDT used for malaria control in Mexico Decades DDT applied (t) Year DDT used in Mexico
  • 4. Impact in Biota Concentration of DDT (ng/g) in species of the food chain in “La Cigüeña”, Chiapas, Mexico (2002) Birds = 232.50 Fish = 24.08 Crabs = 23.84 Sediment = 138.37
  • 5. Impact in the Environment Total DDT (mg/kg) in superficial soil in malaria communities Mexico, 2002 45,000 40,000 35,000 30,000 25,000 20,000 15,000 10,000 5,000 0 Total DDT Average (μg/kg) Total DDT interior Total DDT exterior Ventanilla Cigüeña Lacandona La Ventanilla La Cigüeña Lacandona
  • 6. Impact in Humans DDT blood concentration in children, Mexico (mg/L) 80 70 60 50 40 30 20 10 0 DDT in blood in children "La Cigüeña", Chiapas 2000 2001 2002 2003 2004 Years DDD (μg/L) DDE (μg/L) DDT (μg/L) Mean concentration (mg/L)
  • 7. Impact in Humans DDT, DDE and DDEms levels in breast milk of 30 Mexican mothers (ng/g lipid) Substance Sweden 1992 Mexico 2004 DDT 22 366 DDE 227 1683 DDEms 0.4 3.4
  • 8. General Information PPaarrttiicciippaattiinngg ccoouunnttrriieess Belize, Costa Rica, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, Panama IImmpplleemmeennttiinngg aaggeennccyy •United Nations Environment Programme EExxeeccuuttiinngg aaggeennccyy •Pan American Health Organization (PAHO) •National Governments FFuunnddiinngg PPaarrttnneerrss •Global Environment Facility •National Governments •PAHO •CEC Total 7.165 5.865 0.654 0.200 US$ 13.884 DDuurraattiioonn Three years: August 2003- July 2006
  • 9. Overall Objective • To demonstrate that methods for malaria vector control without DDT or other persistent pesticides are replicable, cost-effective and sustainable thus preventing the reintroduction of DDT in the Region. Components 1. Implementation of demonstration projects and dissemination 2. Strengthening of national institutional capacity to control malaria without DDT 3. Elimination of DDT stockpiles 4. Coordination and management
  • 10. Focal Areas This Project conforms with the Contaminant-based Operational Program No. 10 and will help demonstrate ways of overcoming barriers to the adoption of best practices that limit contamination of the international waters environment. The proposed activities are also consistent with several provisions with adopted Stockholm Convention on Pops.
  • 11. Implementation Strategy • To integrate epidemiology with social sciences, entomology, public health, environment and provision of health care. – Epidemiological stratification with risk approach – Elimination of the persistent parasite – Ecological larvae control with social participation – Control of the adult mosquito with inexpensive techniques and low environmental impact – Sustained sanitation educational program aimed at the community
  • 12. Demonstration projects • Demonstration projects in sites selected • Baseline assessment concluded • Community participation attained
  • 13. Technical Manual Guide for the implementation and demonstration of sustainable alternatives for the integrated control of malaria in Mexico and Central America
  • 15. The Regional Perspective of Malaria in Mexico and Central America in the Context of Epidemiological Stratification Tropical rainforest distribution (red) CONABIO map Mex. 1999 and CIESIN satellite image, 1995 Areas below 800 meters above average sea level. Digital Elevation Model (DEM), USGS, 2001. API by first sub-national level in Mesoamerica (Central America Basic Indicators 2001) and Mexico Rates x 1000 inhabitants by second administrative level (SUAVE, Mex, 2001) The SIGEpi perspective has the purpose of standardizing, integrating, compiling and facilitate the interchange of digital cartographic infrastructure ( data, methods and software) as a foundation for analyzing geographically the data about malaria vector control and DDT residuals.
  • 16. GIS-DDT-GEF Demonstration areas in Central America, GPS survey progress and instrumentation of the SIGEpi Model up to May 2005 Tropical broad leaf rain forest Municipalities with malaria transmission in 2004 Municipalities with malaria transmission in 1960
  • 17. Costa Rica’ s GIS Local Scale Observation Level for Malaria Control Mosquito breeding sites and surrounding positive houses to malaria Progress in the GPS dwellings survey in localities along the border corridor between Costa Rica and Panama Paper map The same map in vector and raster digital format in SIGEpi GPS demonstration Panama Costa Rica
  • 18. From Sketch to Digital Maps in Panama Showing Malaria Houses (red houses) Calculating the number of preventive treatments in the 200 meters surroundings
  • 19. Malaria Stratification and Levels of Analysis in the GIS DDT Model for Honduras, May 2005 API, municipal level 2002 API, locality level 2005 Cases, intra-locality level cases 2005… in SIGEpi • Identification of malaria houses per week • Detection of houses on transmission risk •100 meters proximity • close to a mosquito breeding site • Intervention programming of community actions and focal control and preventive treatments
  • 20. Inventory of DDT and Other POPs Country DDT Other POPs Belize 13.000 0.008 Costa Rica 8.621 0.122 El Salvador 4.672 46.252 Guatemala 15.058 Honduras 3.539 12.490 Mexico 87.000 Nicaragua 0.003 5.647 Panama 4.545 Total 136.438 64.519
  • 21. Organizational Chart Steering Committee 8 Ministers of Health PAHO UNEP CEC CCAD Observers: World Bank, UNDP, NGOs, other cooperation agencies Regional Operational Committee 1 Regional Coordinator 8 Focal Points (Health) 8 National Coordinators Representatives from NGOs and the Civil Society National Committee National Focal Point (Health) National Coordinator Environment Representative Agriculture Representative Customs or Immigration Representative 9 Working Groups Demonstration Projects National Coordinator Focal Point Environment Representative Agriculture representative UNEP/GEF Implementing/Donor Agencies PAHO Executing Agency CEC Cooperation Agency Advisory Committee Universities, Research Institutions Civil Society, Organizations and NGOs with activities related to the project Advisory Committee One representative from each governmental unit Representatives from NGOs and the Civil Society
  • 22. MMaallaarriiaa ccaasseess aanndd hhoouussee sspprraayyiinngg Cases MMééxxiiccoo 11995599 -- 22000044 Houses EERRAADDIICCAATTIIÓÓNN Y e a r DDT CCOONNTTRROOLL 160,000 140,000 120,000 100,000 80,000 60,000 40,000 20,000 0 59 61 63 65 67 69 71 73 75 77 79 81 83 85 87 89 91 93 95 97 99 01 03 7,000 6,000 5,000 4,000 3,000 2,000 1,000 0 Houses Cases Piretroids

Editor's Notes

  1. Thank you mister chairman. DDT was used in the region for much of the second half of the twentieth century, raising the concern on the effects to human and environmental exposure in the areas sprayed with DDT. However, 35 percent of the Mexican and Central American population lives in malaria endemic areas or are at risk of developing this disease. But successful experiences developed in Mexico and Central America during the last years has showed that it is possible to control the malaria vector without using DDT. Next slide please.
  2. This concern shared by the governments of Belize, Costa Rica, El Salvador, Guatemala, Honduras, Mexico Nicaragua and Panama prompted the implementation of this three-year project of regional scope, implemented by the United Nations Environment Programme, executed by the Pan American Health Organization and the national governments and funded by the Global Environment Fund, cash and in kind cooperation from the participating governments, PAHO in kind input and the contribution from the Commission for Environmental Cooperation of North America. Next slide please.
  3. This project seeks to demonstrate that the methods used to control malaria without DDT or other persistent organic pollutants are replicable, effective and sustainable, thus preventing the reintroduction of DDT in the region. There are four different groups of action necessary to address the countries’ needs to lower their vulnerability to using DDT for malaria control. First, the development of nine demonstration projects under specific environmental and socio-economic conditions, with detailed monitoring and evaluation with the participation of environment and health national services and the local communities. Second, to improve the analytical capacity of the national laboratories for the evaluation of exposure to plaguicides; to strengthen the regional and national malaria surveillance systems; to strengthen the institutions providing care for malaria and to implement the geographic information system. Third, update of the national inventories of DDT and other POPs, repackage, shipment and final disposal according to the Stockholm and Basel Conventions and raise political willingness to prevent recurrence of DDT stockpiles. And fourth, Coordination and management. Next slide please.
  4. The strategy for the successful implementation of the project is to integrate epidemiology with social sciences, entomology, public health, environment, health care services and other scientific fields of a model validated by Mexico and enriched by the other countries. The model is based on the epidemiological stratification with a risk approach; the elimination of the persistent parasite; ecological larval control with social participation; control of the adult anopheles with inexpensive techniques and with the lowest impact to the ecosystem; and a sustained program of sanitary education at the community level. Next slide please.
  5. After a brief overview of the project, we will discuss the results of the project. Within the first component, demonstration projects and dissemination: The demonstration communities have been selected according to stratification criteria; organization of area and local technical teams; final phase of the baseline assessment, made with a standardized form and fine-tuning of the field interventions. The pillars of the community and education participation are the community leaders, families, vulnerable groups, NGOs, local governments and the environment, education and migration sector. Currently seven countries have organized the community groups and drafted the local work plans. Next slide please.
  6. Also it was recently published the Guide for the implementation and demonstration of sustainable alternatives for the integrated control of malaria in Mexico and Central America as a joint effort of the Mexican health authorities, CEC, PAHO, and the representatives from the ministries of health of the participating countries. This manual is a standardized guide for the development of the demonstration projects, yet aware and taking into account the particularities of each country. Next slide please.
  7. In relation to dissemination, the project’s webpage is an important tool of communication among stakeholders and a source of information for visitors. Next slide please.
  8. The standardized form for the inventory of DDT and other POPs was made through and agreement with the Regional Institute of Toxicology in Costa Rica and seven countries have concluded data collection, which include information on location, type of pesticide, storage conditions and others. A total of 136.438 metric tons of DDT were found in the region (data from Mexico is preliminary and its based on the PDF-B assessment). Also 64.519 metric tons of other persisntes pollutants were found in the region. Thank you for your attention.
  9. The highest organ of the project is the Steering Committee, which is composed by representatives of the ministries of health, PAHO, UNEP/GEF, CEC, CCAD and observers such as the World Bank, UNDP, NGOs and other relevant cooperation agencies. Meet once a year to approve the work plans of the countries, the terms of reference of the demonstration projects and provide advisory functions. Then, the Regional Operational Committee responsible for overseeing the implementation of the project and composed by the Regional Coordinator, the 8 Focal Points (from the health sector), the 8 National Coordinators and representatives from NGOs and the Civil Society. The next level of organization is the National Committee, composed by the National Focal Point, the National Coordinator and representatives from the ministries of the Environment and Agriculture, as well as a representative from Customs or Immigration Representative. With an Advisory Committee composed by Universities, Research Institutions, the Civil Society, Organizations and NGOs with activities related to the project. The organization at the local level is the Working Groups for each Demonstration Projects, composed by the National Coordinator, the Focal Point and representatives from the ministries of the Environment and Agriculture. With an Advisory Committee with representatives from the local government, NGOs and the Civil Society. Next slide please.