Data science although pre-existing, now days dominates and may do the same in the future. The existence of huge storage space and powerful processors capable of managing corresponding-sized databases, have enabled information to be collected in every workplace, from the medical and engineering sectors to the arts and sports. In this diploma thesis we will stand in the field of professional sport and in particular basketball. Initially basic knowledge about the sport will be presented, some of the information collection tools will be mentioned and we will analyze the importance and role of data in training, in the preparation of athletes and in the decisions of coaches. Subsequently, having collected data using the "REMEDES" system on a specific basketball set of drills, a sports performance evaluation system was developed using the "Python" programming language and various Data Preprocessing and Machine Learning techniques. The purpose of this system is to evaluate as representatively as possible non-athletes, athletes and Basketball athletes in a specific set of drills that obviously concern basketball. During the analysis and through careful monitoring of the results we have drawn some very interesting conclusions that will be presented and interpreted in this report along the way.