Decentralized finance(DeFi) has opened the door for a new generation of high-frequency trading(HFT) in the crypto space. From basic arbitrages to super sophisticated algorithms, we can see HFT bots all across the DeFi space. How does HFT works in DeFi? This session will present some of the core ideas behind HFT algorithms in the DeFi space. We will discuss key building blocks of HTF-DeFi infrastructures, risks and show real trades that explain these concepts. Finally, we will also discuss how the advent of Ethereum 2.0 can change the HFT landscape in DeFi.