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The Neonatal AirwayThe Neonatal Airway
HOSSAM M ATEF;MDHOSSAM M ATEF;MD
SUEZ CANAL UNIVERSITYSUEZ CANAL UNIVERSITY
ANESTHESIA DEPARTANESTHESIA DEPART
Goals of PresentationGoals of Presentation
 Differences between neonatal and adultDifferences between neonatal and adult
airwayairway
 Neonatal intubation technique andNeonatal intubation technique and
equipmentequipment
 Common mistakes and complications ofCommon mistakes and complications of
intubationintubation
 Syndromes commonly associated withSyndromes commonly associated with
difficult neonatal airwaysdifficult neonatal airways
Why do we care?Why do we care?
 Prompt intubation of a distressed neonatePrompt intubation of a distressed neonate
can be life-savingcan be life-saving
 Residents are getting less trainingResidents are getting less training
The Neonatal AirwayThe Neonatal Airway
 Compared to adults,Compared to adults,
structures are…structures are…

SmallerSmaller

More anteriorMore anterior

Epiglottis is floppierEpiglottis is floppier

Larger tongueLarger tongue

Larger occiputLarger occiput

Narrowest portion ofNarrowest portion of
airway is the cricoidairway is the cricoid
Indications for IntubationIndications for Intubation
 In delivery roomIn delivery room

Cardiorespiratory instabilityCardiorespiratory instability

Meconium during birth, with a depressedMeconium during birth, with a depressed
infantinfant

Prematurity requiring need for surfactantPrematurity requiring need for surfactant
therapytherapy

Congenital malformationsCongenital malformations
Indications for IntubationIndications for Intubation
 In NICUIn NICU

Unable to protect airwayUnable to protect airway

Hypercarbic respiratory failureHypercarbic respiratory failure

Hypoxic respiratory failureHypoxic respiratory failure

Therapeutic indicationTherapeutic indication
What do you need?What do you need?
MMonitors - Cardiac and pulse oximetryonitors - Cardiac and pulse oximetry
SSuction - catheteruction - catheter
MMachine - Laryngoscope, ventilator orachine - Laryngoscope, ventilator or
bag/maskbag/mask
AAirway - Endotracheal tubeirway - Endotracheal tube
IIntravenous - Peripheral or central linentravenous - Peripheral or central line
DDrugs --rugs --
Sedation/analgesia/paralysis/atropineSedation/analgesia/paralysis/atropine
Laryngoscope BladesLaryngoscope Blades
 Straight blades areStraight blades are
placedplaced under theunder the
epiglottisepiglottis and used toand used to
lift anteriorly tolift anteriorly to
expose the cords.expose the cords.
 Curved blades areCurved blades are
placed in theplaced in the valeculavalecula
and lifted anteriorly toand lifted anteriorly to
expose the cords.expose the cords.
Macintosh
Miller
Wisconsin
Endotracheal TubesEndotracheal Tubes
 Endotracheal tubes are divided by the sizeEndotracheal tubes are divided by the size
of their internal diameterof their internal diameter
 For neonates endotracheal tube sizeFor neonates endotracheal tube size
roughly corresponds to 1/10roughly corresponds to 1/10thth
ofof
gestational age rounded down to thegestational age rounded down to the
nearest size.nearest size.

For exampleFor example
• A 36 week premie would get a 3.5 ETTA 36 week premie would get a 3.5 ETT
• A 28 week premie would get a 2.5 ETTA 28 week premie would get a 2.5 ETT
Intubation ProcedureIntubation Procedure
 Proper positioningProper positioning

EquipmentEquipment
• Bed and patient at comfortable heightBed and patient at comfortable height
• Suction and meconium aspirator readily availableSuction and meconium aspirator readily available
• Endotracheal tubes not under warmerEndotracheal tubes not under warmer
• All equipment tested and working just prior to useAll equipment tested and working just prior to use

PatientPatient
• Shoulder rollShoulder roll
• Head in sniffing positionHead in sniffing position

Too much hyperextension can make visualization difficultToo much hyperextension can make visualization difficult
Intubation ProcedureIntubation Procedure
 Pre-oxygenate with 100% bag valve maskPre-oxygenate with 100% bag valve mask
ventilationventilation

Contraindicated in known congenitalContraindicated in known congenital
diaphragmatic herniadiaphragmatic hernia
 Apply monitorsApply monitors
 Give drugsGive drugs

Remember minimum atropine doseRemember minimum atropine dose

Ensure ability to bag/mask ventilate beforeEnsure ability to bag/mask ventilate before
paralysisparalysis
Intubation ProcedureIntubation Procedure
 Inserting theInserting the
laryngoscope bladelaryngoscope blade

Hold laryngoscope inHold laryngoscope in
left handleft hand

While standing aboveWhile standing above
the patient, insert thethe patient, insert the
blade in the right sideblade in the right side
of the mouthof the mouth
WITHOUT trying toWITHOUT trying to
visualize the cords.visualize the cords.
Intubation ProcedureIntubation Procedure
 Take a step backTake a step back
 Lower your head toLower your head to
the level of the labelthe level of the label
 Slowly advanceSlowly advance
laryngoscope untillaryngoscope until
you visualize theyou visualize the
epiglottisepiglottis
 Use straight or curvedUse straight or curved
blade appropriatelyblade appropriately
Intubation ProcedureIntubation Procedure
 Visualize the vocalVisualize the vocal
cordscords

Meconium belowMeconium below
cords?cords?

Both moving if notBoth moving if not
paralyzed?paralyzed?

Structurally normal?Structurally normal?
 Pick up endotrachealPick up endotracheal
tube and passtube and pass
between vocal cordsbetween vocal cords
Assessing Endotracheal TubeAssessing Endotracheal Tube
PlacementPlacement
 Direct visualizationDirect visualization
 End tidal COEnd tidal CO22 monitoringmonitoring
 Chest riseChest rise
 AuscultationAuscultation
 ETT vaporETT vapor

Less reliableLess reliable
 Chest X-rayChest X-ray
Intubation ProcedureIntubation Procedure
 Secure endotracheal tube to lip with tapeSecure endotracheal tube to lip with tape

Do not let go of tube until secureDo not let go of tube until secure
 Reassess that endotracheal tube is still inReassess that endotracheal tube is still in
place.place.
 Assess the neonate –Assess the neonate –

Improving? More pink? Heart rateImproving? More pink? Heart rate
increasing?increasing?
 Continue resuscitation – proceed to B andContinue resuscitation – proceed to B and
C….C….
Common ProblemsCommon Problems
 Esophageal IntubationEsophageal Intubation

Blade placed too deep, cords not visualizedBlade placed too deep, cords not visualized
 Tongue obscures visualizationTongue obscures visualization

Sweep tongue to one side with bladeSweep tongue to one side with blade

More anterior liftMore anterior lift
 Cannot see cordsCannot see cords

Head is hyper-extended - repositionHead is hyper-extended - reposition
Common ProblemsCommon Problems
 Cannot intubateCannot intubate

Most neonates can be bag valve maskMost neonates can be bag valve mask
ventilated easilyventilated easily

Call early for anesthesiology assistanceCall early for anesthesiology assistance
• ““Bag ventilating with oxygen can prolong life for aBag ventilating with oxygen can prolong life for a
long time, repeatedly attempting and failinglong time, repeatedly attempting and failing
intubation will not.”intubation will not.”

Surgical airwaySurgical airway
Difficult Neonatal AirwaysDifficult Neonatal Airways
 Abnormal airwayAbnormal airway
 Increasing awareness of problemsIncreasing awareness of problems
beforehand because of neonatalbeforehand because of neonatal
ultrasoundultrasound
 ““Things you can see” versus “Things youThings you can see” versus “Things you
may find”may find”
Difficult Neonatal AirwaysDifficult Neonatal Airways
 Congenital malformationsCongenital malformations

““Things you can see”Things you can see”

Predictable from looking at the patientPredictable from looking at the patient
• Cleft lip and palateCleft lip and palate
• Pierre Robin syndromePierre Robin syndrome
• Treacher Collins syndromeTreacher Collins syndrome
• Goldenhar syndromeGoldenhar syndrome
• Apert and Crouzon SyndromeApert and Crouzon Syndrome
Congenital MalformationsCongenital Malformations
 Cleft Lip and PalateCleft Lip and Palate

Most commonMost common
congenital facecongenital face
malformationmalformation
 Pierre RobinPierre Robin
SequenceSequence

Obstruction is usuallyObstruction is usually
at the nasopharyngealat the nasopharyngeal
levellevel
Congenital MalformationsCongenital Malformations
 Apert and CrouzonApert and Crouzon

Maxillary hypoplasiaMaxillary hypoplasia

NasopharyngealNasopharyngeal
airway compromiseairway compromise
 Goldenhar syndromeGoldenhar syndrome

Unilateral anomaliesUnilateral anomalies

Higher incidence ofHigher incidence of
airway anomaliesairway anomalies
Congenital MalformationsCongenital Malformations
 Treacher CollinsTreacher Collins

ChoanalChoanal
atresia/stenosis moreatresia/stenosis more
commoncommon
 Down’s SyndromeDown’s Syndrome

Subglottic stenosisSubglottic stenosis
more commonmore common

RememberRemember
atlantoaxial instabilityatlantoaxial instability
Difficult Neonatal AirwaysDifficult Neonatal Airways
 Congenital MalformationsCongenital Malformations

““Things you may find”Things you may find”
• LaryngomalaciaLaryngomalacia
• Hemangioma orHemangioma or
LymphangiomaLymphangioma
• Tracheal webTracheal web
• Laryngeal atresiaLaryngeal atresia
• Subglotic stenosisSubglotic stenosis
Congenital MalformationsCongenital Malformations
 LaryngomalaciaLaryngomalacia

A sequence betweenA sequence between
fully formed to atresiafully formed to atresia
Congenital MalformationsCongenital Malformations
 Laryngeal WebLaryngeal Web
 Tracheal AtresiaTracheal Atresia

Survive only ifSurvive only if
tracheoesophagealtracheoesophageal
fistula or emergentfistula or emergent
trachtrach
Congenital MalformationsCongenital Malformations
 Hemangioma orHemangioma or
LymphangiomaLymphangioma

Only about 30%Only about 30%
present at birthpresent at birth
Congenital MalformationsCongenital Malformations
 Subglottic StenosisSubglottic Stenosis
In ReviewIn Review
 Proper positioning is critical for successfulProper positioning is critical for successful
neonatal intubationneonatal intubation
 Call for help early if unable to intubate or for anyCall for help early if unable to intubate or for any
congenital anomaliescongenital anomalies

Continue to provide oxygen with bag valve maskContinue to provide oxygen with bag valve mask
ventilationventilation
 Practice makes perfectPractice makes perfect

It is estimated that you need to perform at least 90It is estimated that you need to perform at least 90
intubations to be able to intubate successfully on theintubations to be able to intubate successfully on the
first or second attempt at least 80% of the timefirst or second attempt at least 80% of the time
 QUESTIONS?QUESTIONS?

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The neonatal airway

  • 1. The Neonatal AirwayThe Neonatal Airway HOSSAM M ATEF;MDHOSSAM M ATEF;MD SUEZ CANAL UNIVERSITYSUEZ CANAL UNIVERSITY ANESTHESIA DEPARTANESTHESIA DEPART
  • 2. Goals of PresentationGoals of Presentation  Differences between neonatal and adultDifferences between neonatal and adult airwayairway  Neonatal intubation technique andNeonatal intubation technique and equipmentequipment  Common mistakes and complications ofCommon mistakes and complications of intubationintubation  Syndromes commonly associated withSyndromes commonly associated with difficult neonatal airwaysdifficult neonatal airways
  • 3. Why do we care?Why do we care?  Prompt intubation of a distressed neonatePrompt intubation of a distressed neonate can be life-savingcan be life-saving  Residents are getting less trainingResidents are getting less training
  • 4. The Neonatal AirwayThe Neonatal Airway  Compared to adults,Compared to adults, structures are…structures are…  SmallerSmaller  More anteriorMore anterior  Epiglottis is floppierEpiglottis is floppier  Larger tongueLarger tongue  Larger occiputLarger occiput  Narrowest portion ofNarrowest portion of airway is the cricoidairway is the cricoid
  • 5. Indications for IntubationIndications for Intubation  In delivery roomIn delivery room  Cardiorespiratory instabilityCardiorespiratory instability  Meconium during birth, with a depressedMeconium during birth, with a depressed infantinfant  Prematurity requiring need for surfactantPrematurity requiring need for surfactant therapytherapy  Congenital malformationsCongenital malformations
  • 6. Indications for IntubationIndications for Intubation  In NICUIn NICU  Unable to protect airwayUnable to protect airway  Hypercarbic respiratory failureHypercarbic respiratory failure  Hypoxic respiratory failureHypoxic respiratory failure  Therapeutic indicationTherapeutic indication
  • 7. What do you need?What do you need? MMonitors - Cardiac and pulse oximetryonitors - Cardiac and pulse oximetry SSuction - catheteruction - catheter MMachine - Laryngoscope, ventilator orachine - Laryngoscope, ventilator or bag/maskbag/mask AAirway - Endotracheal tubeirway - Endotracheal tube IIntravenous - Peripheral or central linentravenous - Peripheral or central line DDrugs --rugs -- Sedation/analgesia/paralysis/atropineSedation/analgesia/paralysis/atropine
  • 8. Laryngoscope BladesLaryngoscope Blades  Straight blades areStraight blades are placedplaced under theunder the epiglottisepiglottis and used toand used to lift anteriorly tolift anteriorly to expose the cords.expose the cords.  Curved blades areCurved blades are placed in theplaced in the valeculavalecula and lifted anteriorly toand lifted anteriorly to expose the cords.expose the cords. Macintosh Miller Wisconsin
  • 9. Endotracheal TubesEndotracheal Tubes  Endotracheal tubes are divided by the sizeEndotracheal tubes are divided by the size of their internal diameterof their internal diameter  For neonates endotracheal tube sizeFor neonates endotracheal tube size roughly corresponds to 1/10roughly corresponds to 1/10thth ofof gestational age rounded down to thegestational age rounded down to the nearest size.nearest size.  For exampleFor example • A 36 week premie would get a 3.5 ETTA 36 week premie would get a 3.5 ETT • A 28 week premie would get a 2.5 ETTA 28 week premie would get a 2.5 ETT
  • 10. Intubation ProcedureIntubation Procedure  Proper positioningProper positioning  EquipmentEquipment • Bed and patient at comfortable heightBed and patient at comfortable height • Suction and meconium aspirator readily availableSuction and meconium aspirator readily available • Endotracheal tubes not under warmerEndotracheal tubes not under warmer • All equipment tested and working just prior to useAll equipment tested and working just prior to use  PatientPatient • Shoulder rollShoulder roll • Head in sniffing positionHead in sniffing position  Too much hyperextension can make visualization difficultToo much hyperextension can make visualization difficult
  • 11. Intubation ProcedureIntubation Procedure  Pre-oxygenate with 100% bag valve maskPre-oxygenate with 100% bag valve mask ventilationventilation  Contraindicated in known congenitalContraindicated in known congenital diaphragmatic herniadiaphragmatic hernia  Apply monitorsApply monitors  Give drugsGive drugs  Remember minimum atropine doseRemember minimum atropine dose  Ensure ability to bag/mask ventilate beforeEnsure ability to bag/mask ventilate before paralysisparalysis
  • 12. Intubation ProcedureIntubation Procedure  Inserting theInserting the laryngoscope bladelaryngoscope blade  Hold laryngoscope inHold laryngoscope in left handleft hand  While standing aboveWhile standing above the patient, insert thethe patient, insert the blade in the right sideblade in the right side of the mouthof the mouth WITHOUT trying toWITHOUT trying to visualize the cords.visualize the cords.
  • 13. Intubation ProcedureIntubation Procedure  Take a step backTake a step back  Lower your head toLower your head to the level of the labelthe level of the label  Slowly advanceSlowly advance laryngoscope untillaryngoscope until you visualize theyou visualize the epiglottisepiglottis  Use straight or curvedUse straight or curved blade appropriatelyblade appropriately
  • 14. Intubation ProcedureIntubation Procedure  Visualize the vocalVisualize the vocal cordscords  Meconium belowMeconium below cords?cords?  Both moving if notBoth moving if not paralyzed?paralyzed?  Structurally normal?Structurally normal?  Pick up endotrachealPick up endotracheal tube and passtube and pass between vocal cordsbetween vocal cords
  • 15. Assessing Endotracheal TubeAssessing Endotracheal Tube PlacementPlacement  Direct visualizationDirect visualization  End tidal COEnd tidal CO22 monitoringmonitoring  Chest riseChest rise  AuscultationAuscultation  ETT vaporETT vapor  Less reliableLess reliable  Chest X-rayChest X-ray
  • 16. Intubation ProcedureIntubation Procedure  Secure endotracheal tube to lip with tapeSecure endotracheal tube to lip with tape  Do not let go of tube until secureDo not let go of tube until secure  Reassess that endotracheal tube is still inReassess that endotracheal tube is still in place.place.  Assess the neonate –Assess the neonate –  Improving? More pink? Heart rateImproving? More pink? Heart rate increasing?increasing?  Continue resuscitation – proceed to B andContinue resuscitation – proceed to B and C….C….
  • 17. Common ProblemsCommon Problems  Esophageal IntubationEsophageal Intubation  Blade placed too deep, cords not visualizedBlade placed too deep, cords not visualized  Tongue obscures visualizationTongue obscures visualization  Sweep tongue to one side with bladeSweep tongue to one side with blade  More anterior liftMore anterior lift  Cannot see cordsCannot see cords  Head is hyper-extended - repositionHead is hyper-extended - reposition
  • 18. Common ProblemsCommon Problems  Cannot intubateCannot intubate  Most neonates can be bag valve maskMost neonates can be bag valve mask ventilated easilyventilated easily  Call early for anesthesiology assistanceCall early for anesthesiology assistance • ““Bag ventilating with oxygen can prolong life for aBag ventilating with oxygen can prolong life for a long time, repeatedly attempting and failinglong time, repeatedly attempting and failing intubation will not.”intubation will not.”  Surgical airwaySurgical airway
  • 19. Difficult Neonatal AirwaysDifficult Neonatal Airways  Abnormal airwayAbnormal airway  Increasing awareness of problemsIncreasing awareness of problems beforehand because of neonatalbeforehand because of neonatal ultrasoundultrasound  ““Things you can see” versus “Things youThings you can see” versus “Things you may find”may find”
  • 20. Difficult Neonatal AirwaysDifficult Neonatal Airways  Congenital malformationsCongenital malformations  ““Things you can see”Things you can see”  Predictable from looking at the patientPredictable from looking at the patient • Cleft lip and palateCleft lip and palate • Pierre Robin syndromePierre Robin syndrome • Treacher Collins syndromeTreacher Collins syndrome • Goldenhar syndromeGoldenhar syndrome • Apert and Crouzon SyndromeApert and Crouzon Syndrome
  • 21. Congenital MalformationsCongenital Malformations  Cleft Lip and PalateCleft Lip and Palate  Most commonMost common congenital facecongenital face malformationmalformation  Pierre RobinPierre Robin SequenceSequence  Obstruction is usuallyObstruction is usually at the nasopharyngealat the nasopharyngeal levellevel
  • 22. Congenital MalformationsCongenital Malformations  Apert and CrouzonApert and Crouzon  Maxillary hypoplasiaMaxillary hypoplasia  NasopharyngealNasopharyngeal airway compromiseairway compromise  Goldenhar syndromeGoldenhar syndrome  Unilateral anomaliesUnilateral anomalies  Higher incidence ofHigher incidence of airway anomaliesairway anomalies
  • 23. Congenital MalformationsCongenital Malformations  Treacher CollinsTreacher Collins  ChoanalChoanal atresia/stenosis moreatresia/stenosis more commoncommon  Down’s SyndromeDown’s Syndrome  Subglottic stenosisSubglottic stenosis more commonmore common  RememberRemember atlantoaxial instabilityatlantoaxial instability
  • 24. Difficult Neonatal AirwaysDifficult Neonatal Airways  Congenital MalformationsCongenital Malformations  ““Things you may find”Things you may find” • LaryngomalaciaLaryngomalacia • Hemangioma orHemangioma or LymphangiomaLymphangioma • Tracheal webTracheal web • Laryngeal atresiaLaryngeal atresia • Subglotic stenosisSubglotic stenosis
  • 25. Congenital MalformationsCongenital Malformations  LaryngomalaciaLaryngomalacia  A sequence betweenA sequence between fully formed to atresiafully formed to atresia
  • 26. Congenital MalformationsCongenital Malformations  Laryngeal WebLaryngeal Web  Tracheal AtresiaTracheal Atresia  Survive only ifSurvive only if tracheoesophagealtracheoesophageal fistula or emergentfistula or emergent trachtrach
  • 27. Congenital MalformationsCongenital Malformations  Hemangioma orHemangioma or LymphangiomaLymphangioma  Only about 30%Only about 30% present at birthpresent at birth
  • 28. Congenital MalformationsCongenital Malformations  Subglottic StenosisSubglottic Stenosis
  • 29. In ReviewIn Review  Proper positioning is critical for successfulProper positioning is critical for successful neonatal intubationneonatal intubation  Call for help early if unable to intubate or for anyCall for help early if unable to intubate or for any congenital anomaliescongenital anomalies  Continue to provide oxygen with bag valve maskContinue to provide oxygen with bag valve mask ventilationventilation  Practice makes perfectPractice makes perfect  It is estimated that you need to perform at least 90It is estimated that you need to perform at least 90 intubations to be able to intubate successfully on theintubations to be able to intubate successfully on the first or second attempt at least 80% of the timefirst or second attempt at least 80% of the time