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Dorothea Lynde Dix (1802 ā€“1887) 
ā€¢ Dorothea Dix ā€“ American 
activist - Superintendent of 
Army Nurses. 
ā€¢ Opened first Lunatic Asylum 
for the mentally ill 
ā€¢ Trenton, New Jersey, 1848 
ā€¢ She suffered debilitating 
mental breakdowns 
ā€¢ Eventually admitted to the 
same Hospital 
WORLD MENTAL HEALTH DAY - 10 October
Therapy for Mental Illness 
ā€¢ Jules Wagner-Jauregg (University of Vienna) 
ā€¢ Observation - Mental symptoms disappeared 
in mental patients ill with Fever 
ā€¢ He injected malarial blood into mentally ill 
patients to induce fever 
ā€¢ Fever - therapy was dangerous 
ā€¢ No effective Malaria Rx 
ā€¢ Killing about 15% of patients 
ā€¢ So it was abandoned 
ā€¢ Received the Nobel Prize in 1927
Phineas Gage 1823 - 1860 
ā€¢ American railroad construction foreman - Blaster 
ā€¢ 1848 - Rock blasting accident with a large iron rod 
3 feet 7 inches long and 3.2cm diameter, 6kg 
ā€¢ Pierced through his head, destroying his brain 
ā€¢ He was conscious and able to walk within minutes 
of the accident. Taken to Hospital
Phineas Gage 1823 - 1860 
ā€¢ Operated for removal of bone pieces and 
part of the brain 
ā€¢ Comatose for 14 days 
ā€¢ Miraculously recovered 
ā€¢ Personality changed after brain injury
The Transformation 
ā€¢ Before ā€“ Hard working responsible 
ā€¢ He was favorite, efficient, capable 
ā€¢ After ā€“ Mind changed, vulgar, indecent 
ā€¢ Psychopath ā€“ Aggressive and violent, 
drinking, lying, brawling, Unacceptable 
ā€¢ Died due to Status Epilepticus 
ā€¢ 12 yrs after his injury 
ā€¢ This case gave newer approaches for 
treatment of Mental Illnesses
Antonio Egas Moniz 1874 ā€“ 1955 
ā€¢ Portuguese Neurologist 
ā€¢ First Cerebral angiography - 1927 
ā€¢ 1935 ā€“ First lobotomy of Frontal Lobe 
ā€¢ To change the mindset of violent patients 
ā€¢ 20 patients who had suffered from anxiety, 
depression, schizophrenia. 
ā€¢ Used crude hammer and chisel
Antonio Egas Moniz 1874 ā€“ 1955 
ā€¢ Drilled holes in the skull on both sides 
ā€¢ Injected alcohol to destroy nerve fibers 
ā€¢ Leucotome ā€“ Extend a metal loop inside to cut 
the brain parts 
ā€¢ Tried on Murder Convicts of the prison 
ā€¢ Shot by one of his patients in spine 
ā€¢ He became paraplegic - on wheelchair
Antonio Egas Moniz 1874 ā€“ 1955 
First Portuguese - Nobel Prize in 1949
Dr. Walter J Freeman 1895 - 1972 
ā€¢ American Physician, Neurologist 
ā€¢ Yale university (Not a Surgeon) 
ā€¢ Lobotomy to disconnect Thalamus 
(Emotional Brain) from the Frontal 
lobe ā€“ (Thinking brain) 
ā€¢ To calm patients emotions and 
stabilize their personalities without 
changing their intelligence and 
motor functions. 
ā€¢ Trans-orbital approach
The Trans-orbital approach 
ā€¢ Ice Pick Lobotomy ā€“ Transorbital 
ā€¢ Electro-convulsive shock before surgery 
ā€¢ To reach the frontal lobe through the tear ducts. 
ā€¢ The Ice-pick would then be scrambled from side 
to side in order to damage the frontal lobe
Transorbital lobotomy 
ā€¢ Blind dissection of the brain 
ā€¢ Lobotomobile ā€“ Operation Van 
ā€¢ High Mortality and Morbidity 
ā€¢ Done in 10 minutes, anywhere, without 
anaesthesia, without asepsis and without the 
assistance of a surgeon. 
ā€¢ Despite a 14 per cent fatality 
rate, Freeman performed 3,439 
lobotomies. 
ā€¢ Total 40000 done in US.
Rosemary Kennedy 
ā€¢ Sister of President John F Kennedy, 23 yrs 
ā€¢ Violent Mood swings and rebellious. 
ā€¢ Erratic behavior in convent school 
ā€¢ Considered psychologically unstable by her family 
ā€¢ 1941 - Lobotomy done by Dr. Freeman to calm her 
ā€¢ She was conscious during the procedure 
ā€¢ They asked her to recite National anthem 
ā€¢ Continued till she stopped responding 
ā€¢ There was a big mistakeā€¦.
Fate of Rosemary Kennedy 
ā€¢ She Became vegetative 
ā€¢ Poor Brain functions like an infant 
ā€¢ Unable to speak or walk 
ā€¢ Lived in Psychiatric hospital 
ā€¢ Died at 86 yrs in same status 
ā€¢ Eunice Kennedy became an activist 
in the field of mental retardation. 
ā€¢ She founded the Special Olympics 
for mentally disabled athletes 
Lobotomies were banned after the death of a patient of 
Dr. Freeman due to brain Haemorrhage - 1967
Charles Whitman 1941 -1966 
ā€¢ Charles Whitman, 25yrs, US Marine 
corps and Engineering student 
ā€¢ Stayed away from his father (Rude) 
ā€¢ Loved his mother and wife 
ā€¢ Good Student of Marine services 
ā€¢ Noticed Sudden change in his behavior, 
consulted five Psychiatrists 
ā€¢ ā€˜I have been a victim of many unusual 
and irrational thoughtsā€™ 
ā€¢ He was consuming large doses of 
Dexdrine ā€“ Amphetamine
The Unexpected fateā€¦ 
ā€¢ 1st Aug 1966 - Killed his mother 
and wife in sleep by stabbing them 
ā€¢ He wrote letters beside his mother 
and wife after killing them. 
ā€¢ He mentioned ā€“ ā€˜He loved them, 
and wanted them to be safe in 
heavenā€™ 
ā€¢ Then he went to the Texas 
University
Texas University Shootout Case 
ā€¢ Went to top of Texas University 
ā€¢ Killed 3 people on the way 
ā€¢ Fired at innocent people for 96min, killing 14 
people and injuring 32. 
ā€¢ He was shot dead by the police
Brain ib6aD 
ā€¢ He had requested for autopsy 
after his death to find out reason 
of his headaches and moods. 
ā€¢ There was a Frontal lobe tumor, 
Astrocytoma pressing on the 
amagdala 
ā€¢ It could have contributed to his 
inability to control his emotions 
and actions. 
ā€¢ Excess of Dexdrine
MALASIAN FLIGHT 370
SPLIT ā€“ BRAIN 
ā€¢ Roger W. Sperry, Neuropsychologist 
ā€¢ Nobel Prize in 1981 
ā€¢ ā€œSplit-Brainā€ studies on cats 
ā€¢ Different functions of Left and Right Brain 
ā€¢ Both sides are involved in each function 
differently 
ā€¢ One side may dominate other 
ā€¢ Personality change with Rt or Lt ?
TEST MY BRAIN
TEST MY BRAIN
START THE TESTā€¦
FIND A HUMAN FIGURE IN HERE..
STROOP EFFECT ā€“ READ THE COLOR
Read Fastā€¦
Count the F
FIND THE MISTAKE
READ THIS
Which Grey is Darker?
In 1981, Israeli artist Isia Leviant 
Made a painting called The Enigma
Hermann grid illusion
Motion-induced blindness
DISTORTION TEST
OPTICAL ILLUSIONS
Mueller-Lyer Illusion
Jastrow Illusion
Kanizsa Triangle
Sander illusion
Ebbinghaus Illusion
Zollner's illusion
A TWIST
LOOK IN THE CENTER 
THE BALL TURNS GREEN?
Four Perfectly Round Circles
Who is he?
ā€¢ Lift your Right foot 
ā€¢ Make Clockwise Circles 
ā€¢ Lift your Right hand 
ā€¢ Draw Number SIX 
ā€¢ Check your Right foot
Bad brain

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Bad brain

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  • 3. Dorothea Lynde Dix (1802 ā€“1887) ā€¢ Dorothea Dix ā€“ American activist - Superintendent of Army Nurses. ā€¢ Opened first Lunatic Asylum for the mentally ill ā€¢ Trenton, New Jersey, 1848 ā€¢ She suffered debilitating mental breakdowns ā€¢ Eventually admitted to the same Hospital WORLD MENTAL HEALTH DAY - 10 October
  • 4. Therapy for Mental Illness ā€¢ Jules Wagner-Jauregg (University of Vienna) ā€¢ Observation - Mental symptoms disappeared in mental patients ill with Fever ā€¢ He injected malarial blood into mentally ill patients to induce fever ā€¢ Fever - therapy was dangerous ā€¢ No effective Malaria Rx ā€¢ Killing about 15% of patients ā€¢ So it was abandoned ā€¢ Received the Nobel Prize in 1927
  • 5. Phineas Gage 1823 - 1860 ā€¢ American railroad construction foreman - Blaster ā€¢ 1848 - Rock blasting accident with a large iron rod 3 feet 7 inches long and 3.2cm diameter, 6kg ā€¢ Pierced through his head, destroying his brain ā€¢ He was conscious and able to walk within minutes of the accident. Taken to Hospital
  • 6. Phineas Gage 1823 - 1860 ā€¢ Operated for removal of bone pieces and part of the brain ā€¢ Comatose for 14 days ā€¢ Miraculously recovered ā€¢ Personality changed after brain injury
  • 7. The Transformation ā€¢ Before ā€“ Hard working responsible ā€¢ He was favorite, efficient, capable ā€¢ After ā€“ Mind changed, vulgar, indecent ā€¢ Psychopath ā€“ Aggressive and violent, drinking, lying, brawling, Unacceptable ā€¢ Died due to Status Epilepticus ā€¢ 12 yrs after his injury ā€¢ This case gave newer approaches for treatment of Mental Illnesses
  • 8. Antonio Egas Moniz 1874 ā€“ 1955 ā€¢ Portuguese Neurologist ā€¢ First Cerebral angiography - 1927 ā€¢ 1935 ā€“ First lobotomy of Frontal Lobe ā€¢ To change the mindset of violent patients ā€¢ 20 patients who had suffered from anxiety, depression, schizophrenia. ā€¢ Used crude hammer and chisel
  • 9. Antonio Egas Moniz 1874 ā€“ 1955 ā€¢ Drilled holes in the skull on both sides ā€¢ Injected alcohol to destroy nerve fibers ā€¢ Leucotome ā€“ Extend a metal loop inside to cut the brain parts ā€¢ Tried on Murder Convicts of the prison ā€¢ Shot by one of his patients in spine ā€¢ He became paraplegic - on wheelchair
  • 10. Antonio Egas Moniz 1874 ā€“ 1955 First Portuguese - Nobel Prize in 1949
  • 11. Dr. Walter J Freeman 1895 - 1972 ā€¢ American Physician, Neurologist ā€¢ Yale university (Not a Surgeon) ā€¢ Lobotomy to disconnect Thalamus (Emotional Brain) from the Frontal lobe ā€“ (Thinking brain) ā€¢ To calm patients emotions and stabilize their personalities without changing their intelligence and motor functions. ā€¢ Trans-orbital approach
  • 12. The Trans-orbital approach ā€¢ Ice Pick Lobotomy ā€“ Transorbital ā€¢ Electro-convulsive shock before surgery ā€¢ To reach the frontal lobe through the tear ducts. ā€¢ The Ice-pick would then be scrambled from side to side in order to damage the frontal lobe
  • 13. Transorbital lobotomy ā€¢ Blind dissection of the brain ā€¢ Lobotomobile ā€“ Operation Van ā€¢ High Mortality and Morbidity ā€¢ Done in 10 minutes, anywhere, without anaesthesia, without asepsis and without the assistance of a surgeon. ā€¢ Despite a 14 per cent fatality rate, Freeman performed 3,439 lobotomies. ā€¢ Total 40000 done in US.
  • 14. Rosemary Kennedy ā€¢ Sister of President John F Kennedy, 23 yrs ā€¢ Violent Mood swings and rebellious. ā€¢ Erratic behavior in convent school ā€¢ Considered psychologically unstable by her family ā€¢ 1941 - Lobotomy done by Dr. Freeman to calm her ā€¢ She was conscious during the procedure ā€¢ They asked her to recite National anthem ā€¢ Continued till she stopped responding ā€¢ There was a big mistakeā€¦.
  • 15. Fate of Rosemary Kennedy ā€¢ She Became vegetative ā€¢ Poor Brain functions like an infant ā€¢ Unable to speak or walk ā€¢ Lived in Psychiatric hospital ā€¢ Died at 86 yrs in same status ā€¢ Eunice Kennedy became an activist in the field of mental retardation. ā€¢ She founded the Special Olympics for mentally disabled athletes Lobotomies were banned after the death of a patient of Dr. Freeman due to brain Haemorrhage - 1967
  • 16. Charles Whitman 1941 -1966 ā€¢ Charles Whitman, 25yrs, US Marine corps and Engineering student ā€¢ Stayed away from his father (Rude) ā€¢ Loved his mother and wife ā€¢ Good Student of Marine services ā€¢ Noticed Sudden change in his behavior, consulted five Psychiatrists ā€¢ ā€˜I have been a victim of many unusual and irrational thoughtsā€™ ā€¢ He was consuming large doses of Dexdrine ā€“ Amphetamine
  • 17. The Unexpected fateā€¦ ā€¢ 1st Aug 1966 - Killed his mother and wife in sleep by stabbing them ā€¢ He wrote letters beside his mother and wife after killing them. ā€¢ He mentioned ā€“ ā€˜He loved them, and wanted them to be safe in heavenā€™ ā€¢ Then he went to the Texas University
  • 18. Texas University Shootout Case ā€¢ Went to top of Texas University ā€¢ Killed 3 people on the way ā€¢ Fired at innocent people for 96min, killing 14 people and injuring 32. ā€¢ He was shot dead by the police
  • 19. Brain ib6aD ā€¢ He had requested for autopsy after his death to find out reason of his headaches and moods. ā€¢ There was a Frontal lobe tumor, Astrocytoma pressing on the amagdala ā€¢ It could have contributed to his inability to control his emotions and actions. ā€¢ Excess of Dexdrine
  • 21. SPLIT ā€“ BRAIN ā€¢ Roger W. Sperry, Neuropsychologist ā€¢ Nobel Prize in 1981 ā€¢ ā€œSplit-Brainā€ studies on cats ā€¢ Different functions of Left and Right Brain ā€¢ Both sides are involved in each function differently ā€¢ One side may dominate other ā€¢ Personality change with Rt or Lt ?
  • 25. FIND A HUMAN FIGURE IN HERE..
  • 26. STROOP EFFECT ā€“ READ THE COLOR
  • 31. Which Grey is Darker?
  • 32. In 1981, Israeli artist Isia Leviant Made a painting called The Enigma
  • 44. LOOK IN THE CENTER THE BALL TURNS GREEN?
  • 47.
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  • 50. ā€¢ Lift your Right foot ā€¢ Make Clockwise Circles ā€¢ Lift your Right hand ā€¢ Draw Number SIX ā€¢ Check your Right foot