3. INTRODUCTION AND CONFIGURATION
Kinetica, from Thermo Scientific, allows users
to perform a range of analysis, from
compartmental analysis to population PK/PD
analysis.
From non-compartmental to population PK/PD
analyses, Kinetica facilitates data analysis and
reporting in a flexible environment. Kinetica
offers fast, high-throughput data analysis for
discovery, preclinical, clinical, drug metabolism
and drug delivery settings.
4. UNDERSTANDING KINETICA BASIC
CONCEPTS
Kinetica is a template-driven system that
provides standardized pharmacokinetic -
pharmacodynamics analysis for drug
development across your organization. The
template design allows you to reuse analysis
settings, enabling you to maintain consistency
among analysts and analyses.
5. KINETICA TEMPLATES
A template is a collection of methods created
and saved as an empty shell for future
analysis.
Kinetica templates offer several advantages:
• High consistency between analyses and
between users.
• Time savings by not having to validate each
user’s analysis.
• Version control between analyses of the
same study.
6. KINETICA TEMPLATES
Kinetica is installed with nine subdirectories
containing validated templates that provide
unique non-compartmental assistant
technology and a multitude of different
standard and advanced PK, PD and PK/PD
models.
• Absorption Kinetics
• Compartmental Fitting
• Convolution/Deconvolution
• Enzyme Kinematics
• In Vivo/In Vitro Correlation
• Non-Compartmental Analyses
• Population Pharmacokinetics
• Protein Binding
• Urine Pharmacokinetics